FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377010976> ?p ?o ?g. }

• W4377010976 endingPage "1581" @default.
• W4377010976 startingPage "1573" @default.
• W4377010976 abstract "Objective: Hepatitis C virus (HCV) co-infection is associated with increased morbidity and mortality in people with HIV (PWH). Sustained virological response (SVR) decreases the risk of HCV-associated morbidity. We compared mortality, risk of AIDS-defining events, and non-AIDS nonliver (NANL) cancers between HCV-co-infected PWH who reached SVR and mono-infected PWH. Design: Adult PWH from 21 cohorts in Europe and North America that collected HCV treatment data were eligible if they were HCV-free at the time of ART initiation. Methods: Up to 10 mono-infected PWH were matched (on age, sex, date of ART start, HIV acquisition route, and being followed at the time of SVR) to each HCV-co-infected PWH who reached SVR. Cox models were used to estimate relative hazards (hazard ratio) of all-cause mortality, AIDS-defining events, and NANL cancers after adjustment. Results: Among 62 495 PWH, 2756 acquired HCV, of whom 649 reached SVR. For 582 of these, at least one mono-infected PWH could be matched, producing a total of 5062 mono-infected PWH. The estimated hazard ratios comparing HCV-co-infected PWH who reached SVR with mono-infected PWH were 0.29 [95% confidence interval (CI) 0.12–0.73] for mortality, 0.85 [0.42–1.74] for AIDS-defining events, and 1.21 [0.86–1.72] for NANL cancer. Conclusion: PWH who reached SVR a short time after HCV acquisition were not at higher risk of overall mortality compared with mono-infected PWH. However, the apparent higher risk of NANL cancers in HCV-co-infected PWH who reached SVR after a DAA-based treatment compared with mono-infected PWH, though compatible with a null association, suggests a need for monitoring of those events following SVR." @default.
• W4377010976 created "2023-05-19" @default.
• W4377010976 creator A5001041075 @default.
• W4377010976 creator A5007543604 @default.
• W4377010976 creator A5013017179 @default.
• W4377010976 creator A5017751675 @default.
• W4377010976 creator A5021731328 @default.
• W4377010976 creator A5032153269 @default.
• W4377010976 creator A5035631466 @default.
• W4377010976 creator A5036999943 @default.
• W4377010976 creator A5037944984 @default.
• W4377010976 creator A5050408475 @default.
• W4377010976 creator A5052635966 @default.
• W4377010976 creator A5054617732 @default.
• W4377010976 creator A5065094327 @default.
• W4377010976 creator A5068835724 @default.
• W4377010976 creator A5079562113 @default.
• W4377010976 creator A5088630101 @default.
• W4377010976 creator A5089446001 @default.
• W4377010976 creator A5091970926 @default.
• W4377010976 date "2023-05-09" @default.
• W4377010976 modified "2023-10-17" @default.
• W4377010976 title "Impact of hepatitis C cure on risk of mortality and morbidity in people with HIV after antiretroviral therapy initiation" @default.
• W4377010976 cites W1621802947 @default.
• W4377010976 cites W1968345917 @default.
• W4377010976 cites W1971370475 @default.
• W4377010976 cites W1971573789 @default.
• W4377010976 cites W1980154502 @default.
• W4377010976 cites W1984948687 @default.
• W4377010976 cites W1989503541 @default.
• W4377010976 cites W2038738704 @default.
• W4377010976 cites W2039452488 @default.
• W4377010976 cites W2051126700 @default.
• W4377010976 cites W2080175347 @default.
• W4377010976 cites W2081571933 @default.
• W4377010976 cites W2089262666 @default.
• W4377010976 cites W2113864802 @default.
• W4377010976 cites W2124248661 @default.
• W4377010976 cites W2140859072 @default.
• W4377010976 cites W2141371166 @default.
• W4377010976 cites W2147437748 @default.
• W4377010976 cites W2167144336 @default.
• W4377010976 cites W2287453238 @default.
• W4377010976 cites W2291726879 @default.
• W4377010976 cites W2325232810 @default.
• W4377010976 cites W2418539241 @default.
• W4377010976 cites W2428104532 @default.
• W4377010976 cites W2440842077 @default.
• W4377010976 cites W2519498039 @default.
• W4377010976 cites W2520869351 @default.
• W4377010976 cites W2560926253 @default.
• W4377010976 cites W2599533358 @default.
• W4377010976 cites W2614048460 @default.
• W4377010976 cites W2693373045 @default.
• W4377010976 cites W2725442401 @default.
• W4377010976 cites W2739110955 @default.
• W4377010976 cites W2895082265 @default.
• W4377010976 cites W3048645592 @default.
• W4377010976 cites W3136550247 @default.
• W4377010976 doi "https://doi.org/10.1097/qad.0000000000003594" @default.
• W4377010976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37199601" @default.
• W4377010976 hasPublicationYear "2023" @default.
• W4377010976 type Work @default.
• W4377010976 citedByCount "0" @default.
• W4377010976 crossrefType "journal-article" @default.
• W4377010976 hasAuthorship W4377010976A5001041075 @default.
• W4377010976 hasAuthorship W4377010976A5007543604 @default.
• W4377010976 hasAuthorship W4377010976A5013017179 @default.
• W4377010976 hasAuthorship W4377010976A5017751675 @default.
• W4377010976 hasAuthorship W4377010976A5021731328 @default.
• W4377010976 hasAuthorship W4377010976A5032153269 @default.
• W4377010976 hasAuthorship W4377010976A5035631466 @default.
• W4377010976 hasAuthorship W4377010976A5036999943 @default.
• W4377010976 hasAuthorship W4377010976A5037944984 @default.
• W4377010976 hasAuthorship W4377010976A5050408475 @default.
• W4377010976 hasAuthorship W4377010976A5052635966 @default.
• W4377010976 hasAuthorship W4377010976A5054617732 @default.
• W4377010976 hasAuthorship W4377010976A5065094327 @default.
• W4377010976 hasAuthorship W4377010976A5068835724 @default.
• W4377010976 hasAuthorship W4377010976A5079562113 @default.
• W4377010976 hasAuthorship W4377010976A5088630101 @default.
• W4377010976 hasAuthorship W4377010976A5089446001 @default.
• W4377010976 hasAuthorship W4377010976A5091970926 @default.
• W4377010976 hasBestOaLocation W43770109762 @default.
• W4377010976 hasConcept C126322002 @default.
• W4377010976 hasConcept C203014093 @default.
• W4377010976 hasConcept C207103383 @default.
• W4377010976 hasConcept C2522874641 @default.
• W4377010976 hasConcept C2776408679 @default.
• W4377010976 hasConcept C2776455275 @default.
• W4377010976 hasConcept C3013748606 @default.
• W4377010976 hasConcept C44249647 @default.
• W4377010976 hasConcept C50382708 @default.
• W4377010976 hasConcept C71924100 @default.
• W4377010976 hasConceptScore W4377010976C126322002 @default.
• W4377010976 hasConceptScore W4377010976C203014093 @default.
• W4377010976 hasConceptScore W4377010976C207103383 @default.
• W4377010976 hasConceptScore W4377010976C2522874641 @default.

• next