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- W4377011206 abstract "Poly(dimethylsiloxane) (PDMS) is used in microfluidics owing to its biocompatibility and simple fabrication. However, its intrinsic hydrophobicity and biofouling inhibit its microfluidic applications. Conformal hydrogel-skin coating for PDMS microchannels, involving the microstamping transfer of the masking layer, is reported herein. A selective uniform hydrogel layer with a thickness of ∼1 μm was coated in diverse PDMS microchannels with a resolution of ∼3 μm, maintaining its structure and hydrophilicity after 180 days (6 months). The wettability transition of PDMS was demonstrated through the switched emulsification in a flow-focusing device (water-in-oil [pristine PDMS] to oil-in-water [hydrophilic PDMS]). A one-step bead-based immunoassay was performed to detect the anti-severe acute respiratory syndrome coronavirus 2 IgG using a hydrogel-skin-coated point-of-care platform." @default.
- W4377011206 created "2023-05-19" @default.
- W4377011206 creator A5018679390 @default.
- W4377011206 creator A5028709932 @default.
- W4377011206 creator A5040777274 @default.
- W4377011206 date "2023-05-18" @default.
- W4377011206 modified "2023-10-16" @default.
- W4377011206 title "Conformal Hydrogel-Skin Coating on a Microfluidic Channel through Microstamping Transfer of the Masking Layer" @default.
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- W4377011206 doi "https://doi.org/10.1021/acs.analchem.3c00812" @default.
- W4377011206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37198732" @default.
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