FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377011355> ?p ?o ?g. }

• W4377011355 abstract "A major current focus in the analysis of protein-protein interaction (PPI) data is how to identify essential proteins. As massive PPI data are available, this warrants the design of efficient computing methods for identifying essential proteins. Previous studies have achieved considerable performance. However, as a consequence of the features of high noise and structural complexity in PPIs, it is still a challenge to further upgrade the performance of the identification methods.This paper proposes an identification method, named CTF, which identifies essential proteins based on edge features including h-quasi-cliques and uv-triangle graphs and the fusion of multiple-source information. We first design an edge-weight function, named EWCT, for computing the topological scores of proteins based on quasi-cliques and triangle graphs. Then, we generate an edge-weighted PPI network using EWCT and dynamic PPI data. Finally, we compute the essentiality of proteins by the fusion of topological scores and three scores of biological information.We evaluated the performance of the CTF method by comparison with 16 other methods, such as MON, PeC, TEGS, and LBCC, the experiment results on three datasets of Saccharomyces cerevisiae show that CTF outperforms the state-of-the-art methods. Moreover, our method indicates that the fusion of other biological information is beneficial to improve the accuracy of identification." @default.
• W4377011355 created "2023-05-19" @default.
• W4377011355 creator A5000356326 @default.
• W4377011355 creator A5021839735 @default.
• W4377011355 creator A5022256556 @default.
• W4377011355 creator A5042399657 @default.
• W4377011355 creator A5079457723 @default.
• W4377011355 creator A5081686251 @default.
• W4377011355 creator A5090863110 @default.
• W4377011355 date "2023-05-17" @default.
• W4377011355 modified "2023-10-16" @default.
• W4377011355 title "Identification of essential proteins based on edge features and the fusion of multiple-source biological information" @default.
• W4377011355 cites W1969545117 @default.
• W4377011355 cites W1970173121 @default.
• W4377011355 cites W1975191997 @default.
• W4377011355 cites W1986310535 @default.
• W4377011355 cites W1999808266 @default.
• W4377011355 cites W2007245700 @default.
• W4377011355 cites W2017975254 @default.
• W4377011355 cites W2025971310 @default.
• W4377011355 cites W2074443723 @default.
• W4377011355 cites W2077386490 @default.
• W4377011355 cites W2087194317 @default.
• W4377011355 cites W2089125183 @default.
• W4377011355 cites W2105089945 @default.
• W4377011355 cites W2119114096 @default.
• W4377011355 cites W2128049108 @default.
• W4377011355 cites W2130790725 @default.
• W4377011355 cites W2142437744 @default.
• W4377011355 cites W2152285853 @default.
• W4377011355 cites W2512143001 @default.
• W4377011355 cites W2517915074 @default.
• W4377011355 cites W2527742284 @default.
• W4377011355 cites W2547262106 @default.
• W4377011355 cites W2792330169 @default.
• W4377011355 cites W2883054023 @default.
• W4377011355 cites W2912802963 @default.
• W4377011355 cites W2945677156 @default.
• W4377011355 cites W2953873015 @default.
• W4377011355 cites W2999995105 @default.
• W4377011355 cites W3005806187 @default.
• W4377011355 cites W3008459824 @default.
• W4377011355 cites W3020679785 @default.
• W4377011355 cites W3024549885 @default.
• W4377011355 cites W3047787866 @default.
• W4377011355 cites W3082122339 @default.
• W4377011355 cites W3136431264 @default.
• W4377011355 cites W3148629189 @default.
• W4377011355 cites W3162389729 @default.
• W4377011355 cites W3175468141 @default.
• W4377011355 cites W4289766530 @default.
• W4377011355 cites W828529927 @default.
• W4377011355 doi "https://doi.org/10.1186/s12859-023-05315-y" @default.
• W4377011355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37198530" @default.
• W4377011355 hasPublicationYear "2023" @default.
• W4377011355 type Work @default.
• W4377011355 citedByCount "0" @default.
• W4377011355 crossrefType "journal-article" @default.
• W4377011355 hasAuthorship W4377011355A5000356326 @default.
• W4377011355 hasAuthorship W4377011355A5021839735 @default.
• W4377011355 hasAuthorship W4377011355A5022256556 @default.
• W4377011355 hasAuthorship W4377011355A5042399657 @default.
• W4377011355 hasAuthorship W4377011355A5079457723 @default.
• W4377011355 hasAuthorship W4377011355A5081686251 @default.
• W4377011355 hasAuthorship W4377011355A5090863110 @default.
• W4377011355 hasBestOaLocation W43770113551 @default.
• W4377011355 hasConcept C115961682 @default.
• W4377011355 hasConcept C116834253 @default.
• W4377011355 hasConcept C124101348 @default.
• W4377011355 hasConcept C14036430 @default.
• W4377011355 hasConcept C154945302 @default.
• W4377011355 hasConcept C162307627 @default.
• W4377011355 hasConcept C28225019 @default.
• W4377011355 hasConcept C41008148 @default.
• W4377011355 hasConcept C59822182 @default.
• W4377011355 hasConcept C70721500 @default.
• W4377011355 hasConcept C78458016 @default.
• W4377011355 hasConcept C86803240 @default.
• W4377011355 hasConcept C99498987 @default.
• W4377011355 hasConceptScore W4377011355C115961682 @default.
• W4377011355 hasConceptScore W4377011355C116834253 @default.
• W4377011355 hasConceptScore W4377011355C124101348 @default.
• W4377011355 hasConceptScore W4377011355C14036430 @default.
• W4377011355 hasConceptScore W4377011355C154945302 @default.
• W4377011355 hasConceptScore W4377011355C162307627 @default.
• W4377011355 hasConceptScore W4377011355C28225019 @default.
• W4377011355 hasConceptScore W4377011355C41008148 @default.
• W4377011355 hasConceptScore W4377011355C59822182 @default.
• W4377011355 hasConceptScore W4377011355C70721500 @default.
• W4377011355 hasConceptScore W4377011355C78458016 @default.
• W4377011355 hasConceptScore W4377011355C86803240 @default.
• W4377011355 hasConceptScore W4377011355C99498987 @default.
• W4377011355 hasFunder F4320321001 @default.
• W4377011355 hasFunder F4320324174 @default.
• W4377011355 hasIssue "1" @default.
• W4377011355 hasLocation W43770113551 @default.
• W4377011355 hasLocation W43770113552 @default.
• W4377011355 hasOpenAccess W4377011355 @default.
• W4377011355 hasPrimaryLocation W43770113551 @default.
• W4377011355 hasRelatedWork W2056182651 @default.

• next