Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377011681> ?p ?o ?g. }
- W4377011681 abstract "Chronic musculoskeletal pain (CMP) is a complex condition that is mainly treated with analgesic drugs. However, antidepressant intervention is also an important factor in the treatment of CMP. Duloxetine is an effective treatment option for patients with CMP as its antidepressant effect. The purpose of this article is to evaluate the efficacy and safety of duloxetine in treating CMP.We searched PubMed, Web of Science, Embase, Cochrane Library from inception to May, 2022. Randomized controlled trials (RCTs) evaluating the efficacy and safety of duloxetine versus placebo in patients with CMP were included. We identified 13 articles and studied a population of 4201 participants in 4 countries.This meta-analysis showed that the duloxetine has statistically significant compared with the placebo control, benefits on 24-hour average pain, living quality, physical function, and global impressions and there was no difference in the incidence of serious adverse event. In general, duloxetine can improve mood and pain level at the same time.This review shows a significant contribution of duloxetine to CMP symptom relief. This meta-analysis improved that duloxetine can significantly reduce the pain level of patients, improve depressive symptoms and global impression, and has no obvious serious adverse reactions. However, additional studies are required to confirm the relationship between psychological diseases and chronic pain and explore their internal links." @default.
- W4377011681 created "2023-05-19" @default.
- W4377011681 creator A5010818765 @default.
- W4377011681 creator A5012488321 @default.
- W4377011681 creator A5034315697 @default.
- W4377011681 creator A5035723558 @default.
- W4377011681 creator A5039962884 @default.
- W4377011681 creator A5070216294 @default.
- W4377011681 creator A5086653612 @default.
- W4377011681 date "2023-05-18" @default.
- W4377011681 modified "2023-09-29" @default.
- W4377011681 title "Efficacy and safety of duloxetine in chronic musculoskeletal pain: a systematic review and meta-analysis" @default.
- W4377011681 cites W1517417769 @default.
- W4377011681 cites W1823142925 @default.
- W4377011681 cites W1883416684 @default.
- W4377011681 cites W1981808732 @default.
- W4377011681 cites W1986137506 @default.
- W4377011681 cites W1988567531 @default.
- W4377011681 cites W1990079987 @default.
- W4377011681 cites W1991536770 @default.
- W4377011681 cites W2014184499 @default.
- W4377011681 cites W2019794987 @default.
- W4377011681 cites W2038978184 @default.
- W4377011681 cites W2057662279 @default.
- W4377011681 cites W2083274218 @default.
- W4377011681 cites W2086769768 @default.
- W4377011681 cites W2093196756 @default.
- W4377011681 cites W2110263281 @default.
- W4377011681 cites W2125435699 @default.
- W4377011681 cites W2128447164 @default.
- W4377011681 cites W2134852288 @default.
- W4377011681 cites W2150481636 @default.
- W4377011681 cites W2164863281 @default.
- W4377011681 cites W2271873799 @default.
- W4377011681 cites W2528113805 @default.
- W4377011681 cites W2556825373 @default.
- W4377011681 cites W2562940003 @default.
- W4377011681 cites W2573419808 @default.
- W4377011681 cites W2702360522 @default.
- W4377011681 cites W2762571688 @default.
- W4377011681 cites W2790175340 @default.
- W4377011681 cites W2795891036 @default.
- W4377011681 cites W2800478556 @default.
- W4377011681 cites W2886654258 @default.
- W4377011681 cites W2896769073 @default.
- W4377011681 cites W2920957060 @default.
- W4377011681 cites W2922356949 @default.
- W4377011681 cites W2947666403 @default.
- W4377011681 cites W2955744844 @default.
- W4377011681 cites W2966892427 @default.
- W4377011681 cites W2968319112 @default.
- W4377011681 cites W2986479575 @default.
- W4377011681 cites W3000989368 @default.
- W4377011681 cites W3093531551 @default.
- W4377011681 cites W3125923815 @default.
- W4377011681 cites W3165354340 @default.
- W4377011681 cites W4225724637 @default.
- W4377011681 cites W4294859811 @default.
- W4377011681 doi "https://doi.org/10.1186/s12891-023-06488-6" @default.
- W4377011681 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37198620" @default.
- W4377011681 hasPublicationYear "2023" @default.
- W4377011681 type Work @default.
- W4377011681 citedByCount "0" @default.
- W4377011681 crossrefType "journal-article" @default.
- W4377011681 hasAuthorship W4377011681A5010818765 @default.
- W4377011681 hasAuthorship W4377011681A5012488321 @default.
- W4377011681 hasAuthorship W4377011681A5034315697 @default.
- W4377011681 hasAuthorship W4377011681A5035723558 @default.
- W4377011681 hasAuthorship W4377011681A5039962884 @default.
- W4377011681 hasAuthorship W4377011681A5070216294 @default.
- W4377011681 hasAuthorship W4377011681A5086653612 @default.
- W4377011681 hasBestOaLocation W43770116811 @default.
- W4377011681 hasConcept C118552586 @default.
- W4377011681 hasConcept C126322002 @default.
- W4377011681 hasConcept C142724271 @default.
- W4377011681 hasConcept C168563851 @default.
- W4377011681 hasConcept C1862650 @default.
- W4377011681 hasConcept C197934379 @default.
- W4377011681 hasConcept C204787440 @default.
- W4377011681 hasConcept C27081682 @default.
- W4377011681 hasConcept C2776478404 @default.
- W4377011681 hasConcept C2780733359 @default.
- W4377011681 hasConcept C2780764818 @default.
- W4377011681 hasConcept C2781118164 @default.
- W4377011681 hasConcept C2910564767 @default.
- W4377011681 hasConcept C71924100 @default.
- W4377011681 hasConcept C95190672 @default.
- W4377011681 hasConceptScore W4377011681C118552586 @default.
- W4377011681 hasConceptScore W4377011681C126322002 @default.
- W4377011681 hasConceptScore W4377011681C142724271 @default.
- W4377011681 hasConceptScore W4377011681C168563851 @default.
- W4377011681 hasConceptScore W4377011681C1862650 @default.
- W4377011681 hasConceptScore W4377011681C197934379 @default.
- W4377011681 hasConceptScore W4377011681C204787440 @default.
- W4377011681 hasConceptScore W4377011681C27081682 @default.
- W4377011681 hasConceptScore W4377011681C2776478404 @default.
- W4377011681 hasConceptScore W4377011681C2780733359 @default.
- W4377011681 hasConceptScore W4377011681C2780764818 @default.
- W4377011681 hasConceptScore W4377011681C2781118164 @default.
- W4377011681 hasConceptScore W4377011681C2910564767 @default.