FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377011728> ?p ?o ?g. }

• W4377011728 abstract "Abstract Background Hypogonadism in older men is often considered as late onset hypogonadism. However, this clinical condition results from primary testicular failure which could be of genetic origin with Klinefelter syndrome being the most common chromosomal abnormality associated with it. Case presentation We report a heterogeneous group of cases who were diagnosed with hypergonadotropic hypogonadism in their adulthood and were found to have rare chromosomal aberrations. All were elderly men (in their 70 s and 80 s) for whom the diagnosis was made during the evaluation of incidental symptoms suggestive of endocrinopathy. The first had hyponatremia; the other two had gynaecomastia and features of hypogonadism noted during admission for various acute medical problems. With respect to their genetic results; the first had a male karyotype with balanced reciprocal translocation between the long arm of chromosome 4 and the short arm of chromosome 7. The second case had a male karotype with one normal X chromosome and an isochrome for the short arm of the Y chromosome. The third case was an XX male with unbalanced translocation between the X & Y chromosomes with retention of the SRY locus. Conclusion Hypergonadotrophic hypogonadism in the elderly, may be due to chromosomal aberrations, resulting in heterogeneous and diverse clinical phenotypes. Vigilance must be exercised when seeing cases with subtle clinical findings. This report suggests that in selected cases of adult hypergonadotropic hypogonadism, chromosomal analysis may be indicated." @default.
• W4377011728 created "2023-05-19" @default.
• W4377011728 creator A5004145571 @default.
• W4377011728 creator A5031965216 @default.
• W4377011728 creator A5054788410 @default.
• W4377011728 creator A5073555488 @default.
• W4377011728 creator A5088071187 @default.
• W4377011728 creator A5088134928 @default.
• W4377011728 creator A5089242935 @default.
• W4377011728 date "2023-05-17" @default.
• W4377011728 modified "2023-10-16" @default.
• W4377011728 title "Hypergonadotropic hypogonadism and chromosomal aberrations: clinical heterogeneity and implications on the health of elderly men, case series" @default.
• W4377011728 cites W151555449 @default.
• W4377011728 cites W1981205098 @default.
• W4377011728 cites W1987241078 @default.
• W4377011728 cites W1993099490 @default.
• W4377011728 cites W2007739913 @default.
• W4377011728 cites W2023303951 @default.
• W4377011728 cites W2025842723 @default.
• W4377011728 cites W2026649568 @default.
• W4377011728 cites W2052770887 @default.
• W4377011728 cites W2096273247 @default.
• W4377011728 cites W2099170245 @default.
• W4377011728 cites W2100952502 @default.
• W4377011728 cites W2104881617 @default.
• W4377011728 cites W2111616426 @default.
• W4377011728 cites W2143059371 @default.
• W4377011728 cites W2171170913 @default.
• W4377011728 cites W2344726973 @default.
• W4377011728 cites W2395893175 @default.
• W4377011728 cites W2783422125 @default.
• W4377011728 cites W2996499933 @default.
• W4377011728 cites W3001934518 @default.
• W4377011728 cites W3208844061 @default.
• W4377011728 cites W8144945 @default.
• W4377011728 doi "https://doi.org/10.1186/s12902-023-01359-6" @default.
• W4377011728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37198592" @default.
• W4377011728 hasPublicationYear "2023" @default.
• W4377011728 type Work @default.
• W4377011728 citedByCount "0" @default.
• W4377011728 crossrefType "journal-article" @default.
• W4377011728 hasAuthorship W4377011728A5004145571 @default.
• W4377011728 hasAuthorship W4377011728A5031965216 @default.
• W4377011728 hasAuthorship W4377011728A5054788410 @default.
• W4377011728 hasAuthorship W4377011728A5073555488 @default.
• W4377011728 hasAuthorship W4377011728A5088071187 @default.
• W4377011728 hasAuthorship W4377011728A5088134928 @default.
• W4377011728 hasAuthorship W4377011728A5089242935 @default.
• W4377011728 hasBestOaLocation W43770117281 @default.
• W4377011728 hasConcept C104317684 @default.
• W4377011728 hasConcept C118552586 @default.
• W4377011728 hasConcept C126322002 @default.
• W4377011728 hasConcept C138626823 @default.
• W4377011728 hasConcept C187212893 @default.
• W4377011728 hasConcept C2776314099 @default.
• W4377011728 hasConcept C2777338322 @default.
• W4377011728 hasConcept C2777688143 @default.
• W4377011728 hasConcept C2777691561 @default.
• W4377011728 hasConcept C2779234561 @default.
• W4377011728 hasConcept C2779683239 @default.
• W4377011728 hasConcept C2780302854 @default.
• W4377011728 hasConcept C30481170 @default.
• W4377011728 hasConcept C50965678 @default.
• W4377011728 hasConcept C53226629 @default.
• W4377011728 hasConcept C54355233 @default.
• W4377011728 hasConcept C71315377 @default.
• W4377011728 hasConcept C71924100 @default.
• W4377011728 hasConcept C86803240 @default.
• W4377011728 hasConceptScore W4377011728C104317684 @default.
• W4377011728 hasConceptScore W4377011728C118552586 @default.
• W4377011728 hasConceptScore W4377011728C126322002 @default.
• W4377011728 hasConceptScore W4377011728C138626823 @default.
• W4377011728 hasConceptScore W4377011728C187212893 @default.
• W4377011728 hasConceptScore W4377011728C2776314099 @default.
• W4377011728 hasConceptScore W4377011728C2777338322 @default.
• W4377011728 hasConceptScore W4377011728C2777688143 @default.
• W4377011728 hasConceptScore W4377011728C2777691561 @default.
• W4377011728 hasConceptScore W4377011728C2779234561 @default.
• W4377011728 hasConceptScore W4377011728C2779683239 @default.
• W4377011728 hasConceptScore W4377011728C2780302854 @default.
• W4377011728 hasConceptScore W4377011728C30481170 @default.
• W4377011728 hasConceptScore W4377011728C50965678 @default.
• W4377011728 hasConceptScore W4377011728C53226629 @default.
• W4377011728 hasConceptScore W4377011728C54355233 @default.
• W4377011728 hasConceptScore W4377011728C71315377 @default.
• W4377011728 hasConceptScore W4377011728C71924100 @default.
• W4377011728 hasConceptScore W4377011728C86803240 @default.
• W4377011728 hasFunder F4320310110 @default.
• W4377011728 hasIssue "1" @default.
• W4377011728 hasLocation W43770117281 @default.
• W4377011728 hasLocation W43770117282 @default.
• W4377011728 hasOpenAccess W4377011728 @default.
• W4377011728 hasPrimaryLocation W43770117281 @default.
• W4377011728 hasRelatedWork W1967913247 @default.
• W4377011728 hasRelatedWork W2117904866 @default.
• W4377011728 hasRelatedWork W2182969522 @default.
• W4377011728 hasRelatedWork W2370664566 @default.
• W4377011728 hasRelatedWork W2374495527 @default.
• W4377011728 hasRelatedWork W2426845271 @default.
• W4377011728 hasRelatedWork W2897809606 @default.

• next