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- W4377013046 abstract "Abstract A highly diastereoselective solvent‐free grinding approach for the construction of dihydrobenzofuranspirooxindole derivatives through a formal [4+1] annulations of α‐chlorooxindoles with salicylaldehydes in the presence of Brønsted base is reported. This transformation proceeds by Darzens‐type epoxidation to give trans ‐form spiro‐epoxyoxindoles, followed by the nucleophilic ring‐opening/an intramolecular cyclization, providing cis‐form dihydrobenzofuran frameworks." @default.
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- W4377013046 date "2023-05-18" @default.
- W4377013046 modified "2023-10-17" @default.
- W4377013046 title "Formal [4+1] annulations of salicylaldehydes with <scp>3‐chlorooxindoles</scp> for diastereoselective construction of dihydrobenzofuranspirooxindoles by solvent‐free grinding" @default.
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- W4377013046 doi "https://doi.org/10.1002/jhet.4674" @default.
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