FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377013469> ?p ?o ?g. }

• W4377013469 endingPage "83" @default.
• W4377013469 startingPage "82" @default.
• W4377013469 abstract "PURPOSE: In vitro studies on platelet function have shown that lower temperatures encourage aggregation and overexpression of the adhesion molecules. Anesthesia guidelines recommend the prevention of hypothermia (T < 36 º). This study aims to explore the impact of intraoperative body temperature on venous thromboembolism (VTE) and flap pedicle thrombosis within 30 days of microsurgical free tissue transfer surgery to the head and neck. METHODS: All patients who underwent head and neck reconstruction with free tissue transfer from January 2012 through March 2022 in a tertiary center were included in this study. Data were collected from a retrospective and prospective held database. Intraoperative temperature readings were extracted electronically in one-minute intervals for each surgery. Non-physiologic readings less than 30 or more than 42 were discarded. A median was calculated for every five consecutive readings to create a five-minute temperature reading. A median value under 36 º was considered an onset of hypothermia. VTE events and thrombosis of the free flap pedicle (arterial or venous) that require revision surgery were the study outcomes, and they were recorded within 30 days of the index surgery. RESULTS: 895 patients were included, and out of those n=300, 34% were females. The mean intraoperative body temperature and Caprini score for the whole cohort were 36.13 ± 1.08 º and 6.54 ± 1.74. The VTE and pedicle thrombosis rates were (n=37, 4.0%) and (n=58, 6%), respectively. The incidence of patients developing at least one onset of hypothermia was (n=720, 80%). The mean number of hypothermia onsets and the mean length of surgery were 52.40 ± 84.80 and 685.12 ± 144.31 minutes, respectively. The mean for Caprini score in those who developed at least one onset of hypothermia did not differ significantly from those who were normothermic (≥ 36 º) for the whole surgery (6.55±1.76 vs. 6.46±1.60, p=0.533). The rate of VTE in those who experienced at least one onset of hypothermia was significantly higher than in those who were normothermic for the whole surgery (n=35/720, 3.9% vs. n=2/175, 0.22%, p=0.026). This association persisted even after controlling for the Caprini score, the number of hypothermic onsets, and the length of surgery in a multivariable regression model (OR, 5.478, 95%CI: 1.222-24.557). In contrast, the rate of free flap pedicle thrombosis was lower in patients who experienced hypothermia than others in the cohort (n=9/175, 1.01% vs. n=49/720, 5.47%). However, the difference failed to reach a statistical significance (p=0.422). CONCLUSIONS: Hypothermia onset is associated with an increased rate of VTE postoperative, even after controlling for the number of hypothermia onsets, Caprini score, and length of surgery. Patients who experienced hypothermia during surgery had a lower incidence of free flap pedicle thrombosis than those who were normothermic throughout the surgery. However, no conclusion can be made about the impact of hypothermia on pedicle thrombosis since the difference failed to reach statistical significance." @default.
• W4377013469 created "2023-05-19" @default.
• W4377013469 creator A5005170783 @default.
• W4377013469 creator A5021565808 @default.
• W4377013469 creator A5023071200 @default.
• W4377013469 creator A5027151008 @default.
• W4377013469 creator A5031747746 @default.
• W4377013469 creator A5037722344 @default.
• W4377013469 creator A5039207076 @default.
• W4377013469 creator A5044924634 @default.
• W4377013469 creator A5074716206 @default.
• W4377013469 date "2023-05-01" @default.
• W4377013469 modified "2023-09-27" @default.
• W4377013469 title "131. The Impact of Intraoperative Temperature on Venous Thromboembolism and Flap Pedicle Thrombosis in Patients Undergoing Head and Neck Microsurgical Reconstruction" @default.
• W4377013469 doi "https://doi.org/10.1097/01.gox.0000938112.32664.4f" @default.
• W4377013469 hasPublicationYear "2023" @default.
• W4377013469 type Work @default.
• W4377013469 citedByCount "0" @default.
• W4377013469 crossrefType "journal-article" @default.
• W4377013469 hasAuthorship W4377013469A5005170783 @default.
• W4377013469 hasAuthorship W4377013469A5021565808 @default.
• W4377013469 hasAuthorship W4377013469A5023071200 @default.
• W4377013469 hasAuthorship W4377013469A5027151008 @default.
• W4377013469 hasAuthorship W4377013469A5031747746 @default.
• W4377013469 hasAuthorship W4377013469A5037722344 @default.
• W4377013469 hasAuthorship W4377013469A5039207076 @default.
• W4377013469 hasAuthorship W4377013469A5044924634 @default.
• W4377013469 hasAuthorship W4377013469A5074716206 @default.
• W4377013469 hasBestOaLocation W43770134691 @default.
• W4377013469 hasConcept C141071460 @default.
• W4377013469 hasConcept C188816634 @default.
• W4377013469 hasConcept C2777390192 @default.
• W4377013469 hasConcept C2779912925 @default.
• W4377013469 hasConcept C2780011451 @default.
• W4377013469 hasConcept C2780868729 @default.
• W4377013469 hasConcept C2781437307 @default.
• W4377013469 hasConcept C3018411727 @default.
• W4377013469 hasConcept C42219234 @default.
• W4377013469 hasConcept C71924100 @default.
• W4377013469 hasConceptScore W4377013469C141071460 @default.
• W4377013469 hasConceptScore W4377013469C188816634 @default.
• W4377013469 hasConceptScore W4377013469C2777390192 @default.
• W4377013469 hasConceptScore W4377013469C2779912925 @default.
• W4377013469 hasConceptScore W4377013469C2780011451 @default.
• W4377013469 hasConceptScore W4377013469C2780868729 @default.
• W4377013469 hasConceptScore W4377013469C2781437307 @default.
• W4377013469 hasConceptScore W4377013469C3018411727 @default.
• W4377013469 hasConceptScore W4377013469C42219234 @default.
• W4377013469 hasConceptScore W4377013469C71924100 @default.
• W4377013469 hasIssue "5S" @default.
• W4377013469 hasLocation W43770134691 @default.
• W4377013469 hasLocation W43770134692 @default.
• W4377013469 hasLocation W43770134693 @default.
• W4377013469 hasOpenAccess W4377013469 @default.
• W4377013469 hasPrimaryLocation W43770134691 @default.
• W4377013469 hasRelatedWork W1541820635 @default.
• W4377013469 hasRelatedWork W2096934095 @default.
• W4377013469 hasRelatedWork W2169507937 @default.
• W4377013469 hasRelatedWork W2275537355 @default.
• W4377013469 hasRelatedWork W2370546721 @default.
• W4377013469 hasRelatedWork W2384020302 @default.
• W4377013469 hasRelatedWork W2392907226 @default.
• W4377013469 hasRelatedWork W2410680488 @default.
• W4377013469 hasRelatedWork W3013084425 @default.
• W4377013469 hasRelatedWork W3029685554 @default.
• W4377013469 hasVolume "11" @default.
• W4377013469 isParatext "false" @default.
• W4377013469 isRetracted "false" @default.
• W4377013469 workType "article" @default.