Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377014380> ?p ?o ?g. }
- W4377014380 abstract "It is unclear how rates of white matter microstructural decline differ between normal aging and abnormal aging.Diffusion MRI data from several well-established longitudinal cohorts of aging [Alzheimer's Neuroimaging Initiative (ADNI), Baltimore Longitudinal Study of Aging (BLSA), Vanderbilt Memory & Aging Project (VMAP)] was free-water corrected and harmonized. This dataset included 1,723 participants (age at baseline: 72.8±8.87 years, 49.5% male) and 4,605 imaging sessions (follow-up time: 2.97±2.09 years, follow-up range: 1-13 years, mean number of visits: 4.42±1.98). Differences in white matter microstructural decline in normal and abnormal agers was assessed.While we found global decline in white matter in normal/abnormal aging, we found that several white matter tracts (e.g., cingulum bundle) were vulnerable to abnormal aging.There is a prevalent role of white matter microstructural decline in aging, and future large-scale studies in this area may further refine our understanding of the underlying neurodegenerative processes.Longitudinal data was free-water corrected and harmonizedGlobal effects of white matter decline were seen in normal and abnormal agingThe free-water metric was most vulnerable to abnormal agingCingulum free-water was the most vulnerable to abnormal aging." @default.
- W4377014380 created "2023-05-19" @default.
- W4377014380 creator A5003112344 @default.
- W4377014380 creator A5004071188 @default.
- W4377014380 creator A5015502914 @default.
- W4377014380 creator A5016815647 @default.
- W4377014380 creator A5022488909 @default.
- W4377014380 creator A5022753100 @default.
- W4377014380 creator A5028369148 @default.
- W4377014380 creator A5037961149 @default.
- W4377014380 creator A5046110345 @default.
- W4377014380 creator A5056838937 @default.
- W4377014380 creator A5065304551 @default.
- W4377014380 creator A5065822809 @default.
- W4377014380 creator A5074841252 @default.
- W4377014380 creator A5075735203 @default.
- W4377014380 creator A5079147812 @default.
- W4377014380 creator A5082570794 @default.
- W4377014380 creator A5088495720 @default.
- W4377014380 creator A5089482025 @default.
- W4377014380 date "2023-05-18" @default.
- W4377014380 modified "2023-10-11" @default.
- W4377014380 title "Leveraging longitudinal diffusion MRI data to quantify differences in white matter microstructural decline in normal and abnormal aging" @default.
- W4377014380 cites W1941705080 @default.
- W4377014380 cites W1970928383 @default.
- W4377014380 cites W1977845408 @default.
- W4377014380 cites W1979876709 @default.
- W4377014380 cites W1981027686 @default.
- W4377014380 cites W1983906797 @default.
- W4377014380 cites W1998185086 @default.
- W4377014380 cites W2028748733 @default.
- W4377014380 cites W2032254014 @default.
- W4377014380 cites W2050781164 @default.
- W4377014380 cites W2051660207 @default.
- W4377014380 cites W2058965862 @default.
- W4377014380 cites W2059095381 @default.
- W4377014380 cites W2069163567 @default.
- W4377014380 cites W2078524519 @default.
- W4377014380 cites W2102391253 @default.
- W4377014380 cites W2112492995 @default.
- W4377014380 cites W2115614582 @default.
- W4377014380 cites W2119980272 @default.
- W4377014380 cites W2126080113 @default.
- W4377014380 cites W2127027593 @default.
- W4377014380 cites W2136040391 @default.
- W4377014380 cites W2136340921 @default.
- W4377014380 cites W2143316684 @default.
- W4377014380 cites W2148828979 @default.
- W4377014380 cites W2293065353 @default.
- W4377014380 cites W2555857041 @default.
- W4377014380 cites W2561810854 @default.
- W4377014380 cites W2595849452 @default.
- W4377014380 cites W2622858369 @default.
- W4377014380 cites W2707928724 @default.
- W4377014380 cites W2737145049 @default.
- W4377014380 cites W2777605016 @default.
- W4377014380 cites W2887719417 @default.
- W4377014380 cites W2907317448 @default.
- W4377014380 cites W2944607361 @default.
- W4377014380 cites W2955356077 @default.
- W4377014380 cites W2969912298 @default.
- W4377014380 cites W2970186575 @default.
- W4377014380 cites W2978584402 @default.
- W4377014380 cites W3005550859 @default.
- W4377014380 cites W3024351134 @default.
- W4377014380 cites W3038220767 @default.
- W4377014380 cites W3127178723 @default.
- W4377014380 cites W3137667308 @default.
- W4377014380 cites W3196925228 @default.
- W4377014380 cites W3214775847 @default.
- W4377014380 cites W4206636852 @default.
- W4377014380 cites W4211238543 @default.
- W4377014380 cites W4214512212 @default.
- W4377014380 cites W4307347541 @default.
- W4377014380 cites W4309507742 @default.
- W4377014380 doi "https://doi.org/10.1101/2023.05.17.541182" @default.
- W4377014380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37292885" @default.
- W4377014380 hasPublicationYear "2023" @default.
- W4377014380 type Work @default.
- W4377014380 citedByCount "1" @default.
- W4377014380 countsByYear W43770143802023 @default.
- W4377014380 crossrefType "posted-content" @default.
- W4377014380 hasAuthorship W4377014380A5003112344 @default.
- W4377014380 hasAuthorship W4377014380A5004071188 @default.
- W4377014380 hasAuthorship W4377014380A5015502914 @default.
- W4377014380 hasAuthorship W4377014380A5016815647 @default.
- W4377014380 hasAuthorship W4377014380A5022488909 @default.
- W4377014380 hasAuthorship W4377014380A5022753100 @default.
- W4377014380 hasAuthorship W4377014380A5028369148 @default.
- W4377014380 hasAuthorship W4377014380A5037961149 @default.
- W4377014380 hasAuthorship W4377014380A5046110345 @default.
- W4377014380 hasAuthorship W4377014380A5056838937 @default.
- W4377014380 hasAuthorship W4377014380A5065304551 @default.
- W4377014380 hasAuthorship W4377014380A5065822809 @default.
- W4377014380 hasAuthorship W4377014380A5074841252 @default.
- W4377014380 hasAuthorship W4377014380A5075735203 @default.
- W4377014380 hasAuthorship W4377014380A5079147812 @default.
- W4377014380 hasAuthorship W4377014380A5082570794 @default.
- W4377014380 hasAuthorship W4377014380A5088495720 @default.
- W4377014380 hasAuthorship W4377014380A5089482025 @default.