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- W4377014468 abstract "Abstract Background Postoperative hypoparathyroidism (HypoPTH) is the most common complication after total thyroidectomy (TT). Risk factors have been identified, but no data about the specialists performing follow-up have been previously reported. Methods The study focused on 1965 patients undergoing TT at a tertiary level academic centre. Anamnestic, surgical, pathological, biochemical and follow-up data were evaluated. HypoPTH was defined by serum concentration of PTH <10 pg/mL in the 1st and/or the 2nd post-operative day. Persistent hypoPTH was defined by hypoPTH at the end of the trial, lasting >6 months. Results Postoperative HypoPTH occurred in 541 patients (28%). At multivariate analysis, reduced preoperative PTH levels, association of lymph-nodal dissection, higher rate of incidentally removed parathyroids and longer duration of the surgery were independent risk factors. With a drop-out of 9% at final follow-up, hypoPTH regressed in 494 (in 6% >6 months after surgery) and persisted in 53 patients (2.7%). Patients having higher product Calcium×PTH levels at 1st post-operative day (OR 0.821; p=<0.001), or undergoing prolonged and direct follow-up by the operating endocrine surgeon team had a significantly lower risk of persistent hypoPTH (2.5% compared to 33% for other specialists) (OR 0.09; p=<0.001). Conclusion Various patients, disease and surgeon-related risk factors may predict increased postoperative HypoPTH. Prolonged and tailored follow-up directly performed by operating endocrine surgeons may significantly reduce the rate of persistent HypoPTH." @default.
- W4377014468 created "2023-05-19" @default.
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- W4377014468 date "2023-05-01" @default.
- W4377014468 modified "2023-10-15" @default.
- W4377014468 title "A-213 PROLONGED AND TAILORED FOLLOW-UP BY ENDOCRINE SURGEONS IS A PROTECTIVE FACTOR AGAINST PERSISTENT POSTOPERATIVE HYPOPARATHYROIDISM. ANALYSIS OF A SERIES OF 1965 CONSECUTIVE PATIENTS" @default.
- W4377014468 doi "https://doi.org/10.1093/bjs/znad100.007" @default.
- W4377014468 hasPublicationYear "2023" @default.
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