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• W4377014552 abstract "Catheter ablation is a pivotal treatment option for patients with recurrent ventricular tachycardia (VT) and electrical storm (ES). There is no published data on the safety and efficacy of catheter ablation of VT using the recently introduced QDOT Micro (QDOT, BW) catheter, and data concerning a direct comparison of different technologies in this setting are scarce. To assess outcomes of CA for VT in patients with structural heart disease using the QDOT catheter, by comparing them to those observed with the Thermocool Smarttouch (TC-ST, BW) catheter. We conducted a dual-center, observational, prospective study including patients with structural heart disease and recurrent VT/ES undergoing catheter ablation with the QDOT catheter. For comparison, a 1:1 propensity score matching was performed to identify patients who underwent VT CA with the TC-ST catheter, using the nearest neighbor method. Propensity score was based on gender, age, etiology of structural heart disease, left ventricular ejection fraction, electrical storm, and number of previous CAs for VT. The primary efficacy outcome was freedom from recurrent VT, as assessed by implantable defibrillator (ICD) interrogation; the primary safety outcome was in-hospital complications. Forty patients were included in the analysis (QDOT, n=20; TC-ST, n=20); baseline clinical characteristics were similar in the two groups (Table), although the use of the QDOT Micro catheter was associated with shorter procedural duration and higher power settings. After a median follow-up of 7 months, survival free from any recurrent VT measured 74 (95% CI, 57-97)% and 69 (95% CI, 51-93)% in the QDOT and TC-ST groups, respectively (log-rank p=0.54, Figure A), while survival free from ICD shocks was 95 (95% CI, 86-100)% versus 84 (95% CI, 69-100)% (log-rank p=0.26, Figure B). There were no major complications in the QDOT group, while three patients (15%) in the TC-ST had a primary safety event (p=0.23; femoral pseudoaneurysm, n=1; cardiac tamponade, n=1; aortic cusp perforation, n=1). In a cohort of patients with structural heart disease and recurrent VT or ES, the novel QDOT ablation catheter had similar efficacy and safety compared to the TC-ST catheter. Remarkably, no major procedural complications were observed with the QDOT catheter, supporting the safety of this novel device in the ventricular milieu." @default.
• W4377014552 created "2023-05-19" @default.
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• W4377014552 date "2023-05-01" @default.
• W4377014552 modified "2023-09-27" @default.
• W4377014552 title "PO-05-041 CATHETER ABLATION OF VT USING THE QDOT MICRO CATHETER – A PROPENSITY-MATCHED DUAL-CENTER COMPARISON WITH THE THERMOCOOL SMARTTOUCH CATHETER" @default.
• W4377014552 doi "https://doi.org/10.1016/j.hrthm.2023.03.1327" @default.
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