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• W4377014623 abstract "Among patients with persistent atrial fibrillation (AF), there is limited data to support posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) to decrease rates of recurrence in persistent atrial fibrillation. There is emerging data to suggest the recurrence rate of atrial fibrillation with cryoballoon ablation is lower in comparison to radiofrequency ablation in patients who underwent contaminant PVI and PWI. To evaluate recurrence rates of AF in patients with persistent AF with concomitant PVI and PWI with cryoballoon ablation in comparison to radiofrequency ablation at single a center. From December 2020 to August 2022, 25 and 98 patients with persistent AF who underwent contaminant PVI and PWI with cryoballoon and radiofrequency ablation, respectively, were included. Patient demographics and recurrence rates were retrospectively analyzed (Table). After mean follow-up of 13 months, recurrence of atrial arrhythmia was lower with cryoballoon ablation than with radiofrequency ablation, which was not statistically significant (2 of 25 [8%] vs. 14 of 98 [14%], p-value 0.52). Both patients in cryoballoon ablation group had recurrent atrial fibrillation. In the radiofrequency group, 11 of 14 (79%) patients had recurrent atrial fibrillation, and 3 of 14 (21%) reoccurred with an atypical atrial flutter. Three patients in the radiofrequency group underwent repeat ablation procedure after recurrence. Repeat electroanatomic mapping demonstrated: focal reconnection in PVI (patient 1), PWI (patient 2), and a mitral annular flutter (patient 3). Among patients with persistent atrial fibrillation, there was a trend towards a lower rate of atrial arrhythmia recurrence with cryoballoon ablation in comparison to radiofrequency ablation in patients who underwent concomitant PVI and PWI. Larger studies are needed to evaluate these findings.Tabled 1CryoballoonN= 25RFN = 98P-ValueBASELINE CHARACTERISTICSAge (mean)69.4 (+/- 9.6)65.6 (+/-8.9)0.33Female12 (48%)31 (32%)0.13BMI (kg/m2)29.1 (+/-4.9)30.0 (+/-6.5)0.56CHA2DS2-Vasc Score (mean)2.5 (+/-1.3)2 (+/-1.6)0.48Mean LA Volume (mL/m2)53 (+/-22)47 (+/-17)0.57Beta-Blockers18 (72%)80 (90%)0.64Anti-Arrhythmic Medications7 (28%)29 (30%)0.47Oral Anticoagulation25 (100%)98/98 (100%)-Diabetes4 (16%)21 (21%)0.55Heart Failure13 (52%)36 (37%)0.16Coronary Artery Disease2 (8%)19 (19%)0.17Cerebrovascular Accident2 (8%)3 (3%)0.78Hypertension20 (80%)72 (73%)0.51Sleep Apnea9 (36%)35 (35%)0.97COPD3 (12%)5 (5%)0.12RECURRENCE RATE2 (8%)14 (14%)0.52 Open table in a new tab" @default.
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• W4377014623 date "2023-05-01" @default.
• W4377014623 modified "2023-10-05" @default.
• W4377014623 title "PO-03-002 OUTCOMES OF CRYOBALLOON ABLATION COMPARED TO RADIOFREQUENCY ABLATION FOR PULMONARY VEIN ISOLATION AND LEFT ATRIAL POSTERIOR WALL ISOLATION IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION – A SINGLE CENTER EXPERIENCE" @default.
• W4377014623 doi "https://doi.org/10.1016/j.hrthm.2023.03.972" @default.
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