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- W4377015053 abstract "The authors sought to evaluate a method for improving radiofrequency (RF) lesion durability using doxorubicin encased in heat-sensitive liposomes (HSL-dox). Using a porcine model, RF ablations were performed in the right atrium after systemic infusion of either HSL-dox or saline control given immediately before mapping and ablation. Lesion geometry was measured with voltage mapping immediately postablation and after 2 weeks of survival. After 2 weeks, lesions demonstrated less regression in scar area in HSL-dox–exposed animals compared with control animals. We demonstrate improved RF lesion durability in animals treated with HSL-dox, and the cardiotoxic effect was more pronounced after RF applications with higher power and longer duration." @default.
- W4377015053 created "2023-05-19" @default.
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- W4377015053 date "2023-08-01" @default.
- W4377015053 modified "2023-09-26" @default.
- W4377015053 title "Same-Day Discharge for Atrial Fibrillation Ablation" @default.
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- W4377015053 doi "https://doi.org/10.1016/j.jacep.2023.05.006" @default.
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