Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377015280> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4377015280 endingPage "38S" @default.
- W4377015280 startingPage "38S" @default.
- W4377015280 abstract "INTRODUCTION: This study sought to determine whether a decentralized, mobile-friendly, virtual model could achieve appropriate enrollment for a pregnancy health study after COVID-19 closed most clinical research. Preterm birth continues to be a significant and growing issue with 2021 rates exceeding 10%. There is urgent need for new research and technology to improve the ability to predict, prevent, and personalize treatment for complications such as preterm birth, preeclampsia, and gestational diabetes. METHODS: This was a prospective, observational study of a cell-free RNA platform utilizing direct-to-participant recruitment via targeted social media from July 2020 to December 2021. The IRB-approved study was open to patients aged 18–45 with a singleton pregnancy in the United States. Participants signed informed consent, provided record release forms, completed a short questionnaire, and scheduled mobile phlebotomy via a web-based platform. RESULTS: One thousand eight hundred ninety-four participants submitted samples in less than 18 months. Because of delays in shipping, insufficient volume, temperature stability, and hemolysis, 63 samples (3.3%) were not useable. Medical records were received for over 85% of participants. The cohort is geographically and ethnically diverse representing 1,220 zip codes across 30 states. CONCLUSION: This work demonstrates a decentralized, mobile-friendly, virtual study is feasible, efficient, scalable, and flexible, enabling clinical research during a global pandemic. The rate of medical records receipt is likely affected by the large quantity of unique providers and hospitals. This is a rapid, patient-accepted way to conduct clinical research as a supplement to traditional enrollment models." @default.
- W4377015280 created "2023-05-19" @default.
- W4377015280 creator A5023312588 @default.
- W4377015280 creator A5025903339 @default.
- W4377015280 creator A5032134280 @default.
- W4377015280 creator A5033175098 @default.
- W4377015280 creator A5062371774 @default.
- W4377015280 creator A5088167807 @default.
- W4377015280 date "2023-05-01" @default.
- W4377015280 modified "2023-09-27" @default.
- W4377015280 title "Decentralized Clinical Trials: A Flexible and Efficient Adjunct to Accelerate Pregnancy Complication Research [ID: 1377487]" @default.
- W4377015280 doi "https://doi.org/10.1097/01.aog.0000930212.00487.8e" @default.
- W4377015280 hasPublicationYear "2023" @default.
- W4377015280 type Work @default.
- W4377015280 citedByCount "0" @default.
- W4377015280 crossrefType "journal-article" @default.
- W4377015280 hasAuthorship W4377015280A5023312588 @default.
- W4377015280 hasAuthorship W4377015280A5025903339 @default.
- W4377015280 hasAuthorship W4377015280A5032134280 @default.
- W4377015280 hasAuthorship W4377015280A5033175098 @default.
- W4377015280 hasAuthorship W4377015280A5062371774 @default.
- W4377015280 hasAuthorship W4377015280A5088167807 @default.
- W4377015280 hasConcept C126322002 @default.
- W4377015280 hasConcept C136764020 @default.
- W4377015280 hasConcept C141071460 @default.
- W4377015280 hasConcept C142724271 @default.
- W4377015280 hasConcept C195910791 @default.
- W4377015280 hasConcept C204787440 @default.
- W4377015280 hasConcept C2777106319 @default.
- W4377015280 hasConcept C2778979077 @default.
- W4377015280 hasConcept C2779234561 @default.
- W4377015280 hasConcept C2779434492 @default.
- W4377015280 hasConcept C41008148 @default.
- W4377015280 hasConcept C46973012 @default.
- W4377015280 hasConcept C512399662 @default.
- W4377015280 hasConcept C535046627 @default.
- W4377015280 hasConcept C54355233 @default.
- W4377015280 hasConcept C545542383 @default.
- W4377015280 hasConcept C68122502 @default.
- W4377015280 hasConcept C71924100 @default.
- W4377015280 hasConcept C86803240 @default.
- W4377015280 hasConceptScore W4377015280C126322002 @default.
- W4377015280 hasConceptScore W4377015280C136764020 @default.
- W4377015280 hasConceptScore W4377015280C141071460 @default.
- W4377015280 hasConceptScore W4377015280C142724271 @default.
- W4377015280 hasConceptScore W4377015280C195910791 @default.
- W4377015280 hasConceptScore W4377015280C204787440 @default.
- W4377015280 hasConceptScore W4377015280C2777106319 @default.
- W4377015280 hasConceptScore W4377015280C2778979077 @default.
- W4377015280 hasConceptScore W4377015280C2779234561 @default.
- W4377015280 hasConceptScore W4377015280C2779434492 @default.
- W4377015280 hasConceptScore W4377015280C41008148 @default.
- W4377015280 hasConceptScore W4377015280C46973012 @default.
- W4377015280 hasConceptScore W4377015280C512399662 @default.
- W4377015280 hasConceptScore W4377015280C535046627 @default.
- W4377015280 hasConceptScore W4377015280C54355233 @default.
- W4377015280 hasConceptScore W4377015280C545542383 @default.
- W4377015280 hasConceptScore W4377015280C68122502 @default.
- W4377015280 hasConceptScore W4377015280C71924100 @default.
- W4377015280 hasConceptScore W4377015280C86803240 @default.
- W4377015280 hasIssue "5S" @default.
- W4377015280 hasLocation W43770152801 @default.
- W4377015280 hasOpenAccess W4377015280 @default.
- W4377015280 hasPrimaryLocation W43770152801 @default.
- W4377015280 hasRelatedWork W1942711488 @default.
- W4377015280 hasRelatedWork W2075777970 @default.
- W4377015280 hasRelatedWork W2082981959 @default.
- W4377015280 hasRelatedWork W2111106415 @default.
- W4377015280 hasRelatedWork W2406602197 @default.
- W4377015280 hasRelatedWork W2586435855 @default.
- W4377015280 hasRelatedWork W2599136485 @default.
- W4377015280 hasRelatedWork W2899356148 @default.
- W4377015280 hasRelatedWork W4312213703 @default.
- W4377015280 hasRelatedWork W46038804 @default.
- W4377015280 hasVolume "141" @default.
- W4377015280 isParatext "false" @default.
- W4377015280 isRetracted "false" @default.
- W4377015280 workType "article" @default.