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- W4377015717 abstract "There is an increased prevalence of atrial fibrillation in patients with chronic liver disease(CLD). The safety and efficacy of left atrial appendage closure (LAAC) with the watchman device on patients with CLD are uncertain. To study the impact of chronic liver disease on patients undergoing watchman procedure The National Inpatient Sample database was queried between 2016 - 2019 to identify hospitalizations who underwent the watchman procedure and classified them based on the presence of CLD. The adjusted odds ratios (aOR) of in-hospital outcomes and resource utilization were calculated using chi-square statistics in the software STATA v.17. Of 61,400 hospitalizations, 1615 (3%) and 59785 (97%) had watchman procedure with and without CLD respectively. CLD patients undergoing the watchman procedure had a significantly high risk of in-hospital mortality (aOR 8.06, 95% CI 2.09-31.00), MACE (aOR 3.61, 95% CI 1.15-11.34), mechanical ventilation (aOR 3.27, 95% CI 1.41-7.58) and longer hospital stay (1.42 ± 2.59 vs. 2.04 ± 3.75 days, p<0.003) when compared with patients without CLD. There was no difference in bleeding, stroke, cardiac tamponade, cardiogenic shock and hospitalization costs among both groups. LAAC with a watchman device in patients with CLD is associated with significantly higher MACCE and in-hospital mortality with no difference in odds of stroke. This underscores the need for appropriate risk stratification prior to the procedure for optimal outcomes." @default.
- W4377015717 created "2023-05-19" @default.
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- W4377015717 date "2023-05-01" @default.
- W4377015717 modified "2023-09-26" @default.
- W4377015717 title "PO-03-236 IMPACT OF CHRONIC LIVER DISEASE ON WATCHMAN IMPLANTATION; INSIGHTS FROM NATIONAL INPATIENT SAMPLE" @default.
- W4377015717 doi "https://doi.org/10.1016/j.hrthm.2023.03.921" @default.
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