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- W4377016035 abstract "Mitral annular disjunction (MAD) is an increasingly recognized entity that usually accompanies mitral valve prolapse (MVP) and is associated with a small risk of ventricular arrhythmias. There are no established ECG findings associated with MAD, and detection of MAD relies primarily on imaging techniques such as echocardiography or MRI. To discern surface ECG clues to the presence of MAD in patients with MVP. We developed a registry of all patients with MVP from 2019 onwards. All echocardiograms and ECGs were reviewed. Exclusion criteria: QRS duration >120ms, presence of left ventricular hypertrophy, frequent PVCs (to remove confounding effects of T wave memory), non-sinus rhythm, and prior mitral valve surgery. Patients were divided into two groups: MVP+MAD and MVP-only. Patients with MAD measuring ≥2 mm in the parasternal long-axis view at end-systole were included in the MVP+MAD group; all other patients were assigned to the MVP-only group. Patients with “pseudo-MAD” (where the mitral leaflet flattens against the atrial wall during ventricular systole) were also assigned to the MVP-only group after review by an experienced echocardiographer. ECGs were analyzed for rate, rhythm, QRS and T axes, the QRS and T wave discordance in the inferior leads, PR, QRS, QT, and QTc. Total=378 patients (MVP+MAD: n=62; MVP-only: n=316). Surface ECG leads II and III showed greater incidence of QRS and T discordance in patients with MVP+MAD compared to MVP-only (Lead II: p=0.038; Lead III: p=0.0125, see Table 1). MVP + MAD patients, compared to MVP-only patients, show a greater incidence of QRS-T discordance in inferior leads. The absence of QRS-T discordance in the inferior leads excludes the presence of MAD with an NPV of 86% for Lead II and 88% for Lead III." @default.
- W4377016035 created "2023-05-19" @default.
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- W4377016035 date "2023-05-01" @default.
- W4377016035 modified "2023-10-01" @default.
- W4377016035 title "PO-05-157 DOES THE SURFACE ECG PROVIDE CLUES TO THE PRESENCE OF MITRAL ANNULAR DISJUNCTION IN PATIENTS WITH MITRAL VALVE PROLAPSE?" @default.
- W4377016035 doi "https://doi.org/10.1016/j.hrthm.2023.03.1371" @default.
- W4377016035 hasPublicationYear "2023" @default.
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