Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377016039> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4377016039 endingPage "S723" @default.
- W4377016039 startingPage "S723" @default.
- W4377016039 abstract "A critical feature of an Insertable Cardiac Monitor (ICM) is to identify clinically significant pauses/bradycardic events in patients (pts) with unexplained syncope. Reducing the number of false positive pause episodes will reduce the clinic review workload. To evaluate an enhanced pause detection algorithm and reduce the clinical burden of evaluating pause episodes while maintaining high relative sensitivity and increasing specificity. The development set consisted of 1033 real world stored LUX-Dx (Boston Scientific) ICM pause events (347 pts) which were selected to include more episodes with low signal to noise ratio (SNR). Another independent test set of 728 real world stored Pause events (93 pts) was randomly selected from a large pool of sequestered patient episode data and adjudicated by two experts until agreement as to specificity. The LUX-Dx pause algorithm uses a proprietary two-step detect/confirm process: step 1 detects when an R-R interval is longer than a programmed threshold, and step 2 confirms (or rejects) a suspected pause after analyzing for broadband myopotential noise and signal-to-noise ratios (SNR) (undersensing). Using the development set (1033 episodes), we have enhanced this algorithm to reject false positive pauses caused by noise and low amplitude signals. The false positive (FP) reduction was 62.5% in the Development set and 48.6% in the Test set. Further, the pt-level reduction in FP episodes ranged from 31.3 - 74.1%. No previously detected true positives were eliminated by the enhanced algorithm in either the development or test sets. This enhanced pause detection algorithm maintained high relative sensitivity, and exhibited a substantial reduction in false pauses, which would decrease the review burden in ICM device clinics while preserving sensitivity to detect clinically important events.Tabled 1DatasetNumber of PatientsNumber of episodesRelative Sensitivity (%)Reduction in FP episodes (%)Reduction in patients with FP events (%)Development347103310062.574.1Test9372810048.631.3 Open table in a new tab" @default.
- W4377016039 created "2023-05-19" @default.
- W4377016039 creator A5007660587 @default.
- W4377016039 creator A5046762326 @default.
- W4377016039 creator A5048503104 @default.
- W4377016039 creator A5073070928 @default.
- W4377016039 creator A5073145202 @default.
- W4377016039 date "2023-05-01" @default.
- W4377016039 modified "2023-10-01" @default.
- W4377016039 title "PO-05-085 ENHANCED PAUSE ALGORITHM FOR INSERTABLE CARDIAC MONITOR REDUCES CLINICAL REVIEW BURDEN" @default.
- W4377016039 doi "https://doi.org/10.1016/j.hrthm.2023.03.1498" @default.
- W4377016039 hasPublicationYear "2023" @default.
- W4377016039 type Work @default.
- W4377016039 citedByCount "0" @default.
- W4377016039 crossrefType "journal-article" @default.
- W4377016039 hasAuthorship W4377016039A5007660587 @default.
- W4377016039 hasAuthorship W4377016039A5046762326 @default.
- W4377016039 hasAuthorship W4377016039A5048503104 @default.
- W4377016039 hasAuthorship W4377016039A5073070928 @default.
- W4377016039 hasAuthorship W4377016039A5073145202 @default.
- W4377016039 hasBestOaLocation W43770160391 @default.
- W4377016039 hasConcept C11413529 @default.
- W4377016039 hasConcept C115961682 @default.
- W4377016039 hasConcept C126322002 @default.
- W4377016039 hasConcept C154945302 @default.
- W4377016039 hasConcept C177264268 @default.
- W4377016039 hasConcept C199360897 @default.
- W4377016039 hasConcept C41008148 @default.
- W4377016039 hasConcept C64869954 @default.
- W4377016039 hasConcept C71924100 @default.
- W4377016039 hasConcept C99498987 @default.
- W4377016039 hasConceptScore W4377016039C11413529 @default.
- W4377016039 hasConceptScore W4377016039C115961682 @default.
- W4377016039 hasConceptScore W4377016039C126322002 @default.
- W4377016039 hasConceptScore W4377016039C154945302 @default.
- W4377016039 hasConceptScore W4377016039C177264268 @default.
- W4377016039 hasConceptScore W4377016039C199360897 @default.
- W4377016039 hasConceptScore W4377016039C41008148 @default.
- W4377016039 hasConceptScore W4377016039C64869954 @default.
- W4377016039 hasConceptScore W4377016039C71924100 @default.
- W4377016039 hasConceptScore W4377016039C99498987 @default.
- W4377016039 hasIssue "5" @default.
- W4377016039 hasLocation W43770160391 @default.
- W4377016039 hasOpenAccess W4377016039 @default.
- W4377016039 hasPrimaryLocation W43770160391 @default.
- W4377016039 hasRelatedWork W1988109548 @default.
- W4377016039 hasRelatedWork W2027930466 @default.
- W4377016039 hasRelatedWork W2064591405 @default.
- W4377016039 hasRelatedWork W2085076881 @default.
- W4377016039 hasRelatedWork W2148425737 @default.
- W4377016039 hasRelatedWork W2167840209 @default.
- W4377016039 hasRelatedWork W2592098600 @default.
- W4377016039 hasRelatedWork W2592730790 @default.
- W4377016039 hasRelatedWork W3029113222 @default.
- W4377016039 hasRelatedWork W3138901752 @default.
- W4377016039 hasVolume "20" @default.
- W4377016039 isParatext "false" @default.
- W4377016039 isRetracted "false" @default.
- W4377016039 workType "article" @default.