FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377016210> ?p ?o ?g. }

• W4377016210 endingPage "S170" @default.
• W4377016210 startingPage "S170" @default.
• W4377016210 abstract "The initiation of sotalol for cardiac arrhythmias has largely required in-patient stay due to the possibility of QT interval prolongation and concern for ventricular arrhythmia. Clinical outcomes of patients starting sotalol as outpatients have not been well studied. To the best of our knowledge, we report this as the largest cohort of outpatient initiation of sotalol. Evaluate the safety and tolerability of initiating sotalol as an outpatient. We performed a retrospective chart review of patients being initiated on sotalol as an outpatient within the Northeast Georgia Health System from October 2017 to January 2022. We evaluated the baseline characteristics of our population including demographics and risk factors. Post sotalol initiation outcomes included QT interval, cardiac arrest, bradycardia, device placements, and death. The follow-up period was restricted to 90 days post-initiation of sotalol. Analysis was performed using JMP Pro (version 16.0.0, SAS Institute Cary NC). We identified total of 720 patients with outpatient initiation of sotalol. The mean age was 69.5 ± 11.1, and 415 (57.6%) were men. Baseline characteristics before sotalol initiation showed mean QT of 402 ms, creatinine of 1.07, and potassium of 4. Mean LVEF of 55.9 ± 8.3, 10.1% with history of bradycardia and 1.0% had history of high-grade AV block. The most commonly started sotalol dose was 80 mg twice daily in 81.3% of the patients. The mean QT interval post sotalol loading was 418 ms. Within the 90-day follow-up period, 2 patients (0.3%) had reported cardiac arrests; one had known cardiomyopathy with low EF of 30% and second had discontinued sotalol one week before the event. 1 death occurred due to PEA; patient with advanced cardiomyopathy admitted with worsening CHF. 10 (1.4%) patients had pacemakers implanted within 90 days of drug initiation; 7/10 of these patients had marked bradycardia before sotalol initiation with pre plans of pacemaker implant after sotalol initiation. 1 patient had ICD implantation after sotalol initiation for persistent LV dysfunction. Retrospective review of our data suggests that in a controlled clinical setting, sotalol initiation can be safely done as an outpatient without increasing adverse events. These patients generally had normal renal function, electrolytes, and QT interval at baseline. Further randomized trials are needed to corroborate these findings in a wider population." @default.
• W4377016210 created "2023-05-19" @default.
• W4377016210 creator A5001987219 @default.
• W4377016210 creator A5002918024 @default.
• W4377016210 creator A5004905233 @default.
• W4377016210 creator A5006254881 @default.
• W4377016210 creator A5023338166 @default.
• W4377016210 creator A5034296088 @default.
• W4377016210 creator A5056403443 @default.
• W4377016210 creator A5058273408 @default.
• W4377016210 creator A5060072067 @default.
• W4377016210 creator A5069268891 @default.
• W4377016210 creator A5074144079 @default.
• W4377016210 creator A5091971845 @default.
• W4377016210 creator A5091971846 @default.
• W4377016210 creator A5091971847 @default.
• W4377016210 date "2023-05-01" @default.
• W4377016210 modified "2023-10-16" @default.
• W4377016210 title "PO-01-135 SAFETY AND TOLERABILITY OF INITIATING ORAL SOTALOL AS OUTPATIENT" @default.
• W4377016210 doi "https://doi.org/10.1016/j.hrthm.2023.03.544" @default.
• W4377016210 hasPublicationYear "2023" @default.
• W4377016210 type Work @default.
• W4377016210 citedByCount "0" @default.
• W4377016210 crossrefType "journal-article" @default.
• W4377016210 hasAuthorship W4377016210A5001987219 @default.
• W4377016210 hasAuthorship W4377016210A5002918024 @default.
• W4377016210 hasAuthorship W4377016210A5004905233 @default.
• W4377016210 hasAuthorship W4377016210A5006254881 @default.
• W4377016210 hasAuthorship W4377016210A5023338166 @default.
• W4377016210 hasAuthorship W4377016210A5034296088 @default.
• W4377016210 hasAuthorship W4377016210A5056403443 @default.
• W4377016210 hasAuthorship W4377016210A5058273408 @default.
• W4377016210 hasAuthorship W4377016210A5060072067 @default.
• W4377016210 hasAuthorship W4377016210A5069268891 @default.
• W4377016210 hasAuthorship W4377016210A5074144079 @default.
• W4377016210 hasAuthorship W4377016210A5091971845 @default.
• W4377016210 hasAuthorship W4377016210A5091971846 @default.
• W4377016210 hasAuthorship W4377016210A5091971847 @default.
• W4377016210 hasBestOaLocation W43770162101 @default.
• W4377016210 hasConcept C118441451 @default.
• W4377016210 hasConcept C126322002 @default.
• W4377016210 hasConcept C164705383 @default.
• W4377016210 hasConcept C197934379 @default.
• W4377016210 hasConcept C2776639339 @default.
• W4377016210 hasConcept C2777495988 @default.
• W4377016210 hasConcept C2777953023 @default.
• W4377016210 hasConcept C2778375690 @default.
• W4377016210 hasConcept C2779161974 @default.
• W4377016210 hasConcept C2780486423 @default.
• W4377016210 hasConcept C42219234 @default.
• W4377016210 hasConcept C71924100 @default.
• W4377016210 hasConcept C84393581 @default.
• W4377016210 hasConceptScore W4377016210C118441451 @default.
• W4377016210 hasConceptScore W4377016210C126322002 @default.
• W4377016210 hasConceptScore W4377016210C164705383 @default.
• W4377016210 hasConceptScore W4377016210C197934379 @default.
• W4377016210 hasConceptScore W4377016210C2776639339 @default.
• W4377016210 hasConceptScore W4377016210C2777495988 @default.
• W4377016210 hasConceptScore W4377016210C2777953023 @default.
• W4377016210 hasConceptScore W4377016210C2778375690 @default.
• W4377016210 hasConceptScore W4377016210C2779161974 @default.
• W4377016210 hasConceptScore W4377016210C2780486423 @default.
• W4377016210 hasConceptScore W4377016210C42219234 @default.
• W4377016210 hasConceptScore W4377016210C71924100 @default.
• W4377016210 hasConceptScore W4377016210C84393581 @default.
• W4377016210 hasIssue "5" @default.
• W4377016210 hasLocation W43770162101 @default.
• W4377016210 hasOpenAccess W4377016210 @default.
• W4377016210 hasPrimaryLocation W43770162101 @default.
• W4377016210 hasRelatedWork W147646773 @default.
• W4377016210 hasRelatedWork W1991313862 @default.
• W4377016210 hasRelatedWork W2042618889 @default.
• W4377016210 hasRelatedWork W2064841627 @default.
• W4377016210 hasRelatedWork W2087965295 @default.
• W4377016210 hasRelatedWork W2169811683 @default.
• W4377016210 hasRelatedWork W2793417236 @default.
• W4377016210 hasRelatedWork W3135401368 @default.
• W4377016210 hasRelatedWork W50690958 @default.
• W4377016210 hasRelatedWork W87686535 @default.
• W4377016210 hasVolume "20" @default.
• W4377016210 isParatext "false" @default.
• W4377016210 isRetracted "false" @default.
• W4377016210 workType "article" @default.