Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377016543> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4377016543 endingPage "S194" @default.
- W4377016543 startingPage "S194" @default.
- W4377016543 abstract "Atrial fibrillation (AF) is associated with mortality, morbidity, and medical costs. Despite the increasing public health importance of AF, race-specific disease distributions and associations between clinical risk factors and AF have received limited attention. This study aimed to compare established associations between risk factors and AF in white Europeans from the UK Biobank and Asian subjects from the Korean NHIS-HEALS (National Health Insurance Service-Health Screening) study. This study included 402,229 and 484,406 patients without a diagnosis of nonvalvular AF from the Korean NHIS-HEALS cohort and UK Biobank, respectively. The incidence of AF, its associations with mortality, common risk factors, biomarkers, prevalent cardiovascular disease, and their attributable risk by race were examined. The median follow-up time was 11.8 years (interquartile range [IQR] 11.1–12.6) in the UK Biobank and 7.6 years (IQR 7.0–8.2) in the Korean NHIS-HEALS. Fewer AF cases were observed in Korean NHIS-HEALS (N=9182; 2.3%) than in the UK Biobank (N=25312; 5.2%). Cardiovascular risk factors, comorbidities, and glucose levels were associated with an increased risk of new-onset AF in both cohorts, with significant interactions by country for associations with body mass index (BMI), economic status, smoking history, history of heart failure, and cholesterol level. BMI was more strongly related to new-onset AF in UK Biobank [hazard ratio (HR), 1.31; 95% confidence interval (CI), 1.29–1.33] compared to Korean NHIS-HEALS (HR, 1.11; 95% CI, 1.09–1.14), with a relative risk ratio of 1.18 (95% CI, 1.15–1.21). Total cholesterol was inversely associated with incident AF in both cohorts (HR, 0.86; 95% CI, 0.85–0.87 versus 0.91; 95% CI, 0.89–0.93 in Korean NHIS-HEALS), relative risk ratio 0.95 (95% CI, 0.92–0.97). Attributable risk proportion of most classical risk factors were similar in both the studies. In this first large-scale comparison of Caucasian and Asian populations, the cumulative risk of developing AF was higher in the UK than in Korea over most of their lifespan. Higher BMI, smoking, history of heart failure, and lower total cholesterol levels were associated with a higher risk of AF in the UK than in Asians." @default.
- W4377016543 created "2023-05-19" @default.
- W4377016543 creator A5013435322 @default.
- W4377016543 creator A5029689323 @default.
- W4377016543 creator A5030835183 @default.
- W4377016543 creator A5037864229 @default.
- W4377016543 creator A5038405190 @default.
- W4377016543 creator A5057554500 @default.
- W4377016543 creator A5071164102 @default.
- W4377016543 creator A5073037699 @default.
- W4377016543 creator A5073912011 @default.
- W4377016543 creator A5085354764 @default.
- W4377016543 date "2023-05-01" @default.
- W4377016543 modified "2023-09-29" @default.
- W4377016543 title "PO-01-226 RACIAL DIFFERENCES AND SIMILARITIES IN ATRIAL FIBRILLATION EPIDEMIOLOGY, RISK FACTORS, AND MORTALITY IN COMMUNITY-BASED COHORTS: RESULTS FROM THE KOREAN NHIS-HEALS AND UK BIOBANK STUDIES" @default.
- W4377016543 doi "https://doi.org/10.1016/j.hrthm.2023.03.589" @default.
- W4377016543 hasPublicationYear "2023" @default.
- W4377016543 type Work @default.
- W4377016543 citedByCount "0" @default.
- W4377016543 crossrefType "journal-article" @default.
- W4377016543 hasAuthorship W4377016543A5013435322 @default.
- W4377016543 hasAuthorship W4377016543A5029689323 @default.
- W4377016543 hasAuthorship W4377016543A5030835183 @default.
- W4377016543 hasAuthorship W4377016543A5037864229 @default.
- W4377016543 hasAuthorship W4377016543A5038405190 @default.
- W4377016543 hasAuthorship W4377016543A5057554500 @default.
- W4377016543 hasAuthorship W4377016543A5071164102 @default.
- W4377016543 hasAuthorship W4377016543A5073037699 @default.
- W4377016543 hasAuthorship W4377016543A5073912011 @default.
- W4377016543 hasAuthorship W4377016543A5085354764 @default.
- W4377016543 hasBestOaLocation W43770165431 @default.
- W4377016543 hasConcept C107130276 @default.
- W4377016543 hasConcept C116567970 @default.
- W4377016543 hasConcept C119060515 @default.
- W4377016543 hasConcept C120665830 @default.
- W4377016543 hasConcept C121332964 @default.
- W4377016543 hasConcept C126322002 @default.
- W4377016543 hasConcept C144024400 @default.
- W4377016543 hasConcept C149923435 @default.
- W4377016543 hasConcept C201903717 @default.
- W4377016543 hasConcept C207103383 @default.
- W4377016543 hasConcept C2779161974 @default.
- W4377016543 hasConcept C2780221984 @default.
- W4377016543 hasConcept C44249647 @default.
- W4377016543 hasConcept C60644358 @default.
- W4377016543 hasConcept C61511704 @default.
- W4377016543 hasConcept C71924100 @default.
- W4377016543 hasConcept C72563966 @default.
- W4377016543 hasConcept C86803240 @default.
- W4377016543 hasConceptScore W4377016543C107130276 @default.
- W4377016543 hasConceptScore W4377016543C116567970 @default.
- W4377016543 hasConceptScore W4377016543C119060515 @default.
- W4377016543 hasConceptScore W4377016543C120665830 @default.
- W4377016543 hasConceptScore W4377016543C121332964 @default.
- W4377016543 hasConceptScore W4377016543C126322002 @default.
- W4377016543 hasConceptScore W4377016543C144024400 @default.
- W4377016543 hasConceptScore W4377016543C149923435 @default.
- W4377016543 hasConceptScore W4377016543C201903717 @default.
- W4377016543 hasConceptScore W4377016543C207103383 @default.
- W4377016543 hasConceptScore W4377016543C2779161974 @default.
- W4377016543 hasConceptScore W4377016543C2780221984 @default.
- W4377016543 hasConceptScore W4377016543C44249647 @default.
- W4377016543 hasConceptScore W4377016543C60644358 @default.
- W4377016543 hasConceptScore W4377016543C61511704 @default.
- W4377016543 hasConceptScore W4377016543C71924100 @default.
- W4377016543 hasConceptScore W4377016543C72563966 @default.
- W4377016543 hasConceptScore W4377016543C86803240 @default.
- W4377016543 hasIssue "5" @default.
- W4377016543 hasLocation W43770165431 @default.
- W4377016543 hasOpenAccess W4377016543 @default.
- W4377016543 hasPrimaryLocation W43770165431 @default.
- W4377016543 hasRelatedWork W2139745967 @default.
- W4377016543 hasRelatedWork W2174666533 @default.
- W4377016543 hasRelatedWork W2442149795 @default.
- W4377016543 hasRelatedWork W2738948630 @default.
- W4377016543 hasRelatedWork W2942060080 @default.
- W4377016543 hasRelatedWork W2947523721 @default.
- W4377016543 hasRelatedWork W3005621648 @default.
- W4377016543 hasRelatedWork W3037194828 @default.
- W4377016543 hasRelatedWork W3122724326 @default.
- W4377016543 hasRelatedWork W4212816370 @default.
- W4377016543 hasVolume "20" @default.
- W4377016543 isParatext "false" @default.
- W4377016543 isRetracted "false" @default.
- W4377016543 workType "article" @default.