Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377019567> ?p ?o ?g. }
- W4377019567 endingPage "109649" @default.
- W4377019567 startingPage "109649" @default.
- W4377019567 abstract "The number of regulatory T cells (Tregs) and how they behave in the pathogenesis of atopic dermatitis (AD) are still controversial. We identified and quantified Tregs, mite-specific Tregs, and mite-specific effector T cells (Teffs) in patients with AD and healthy controls (HCs). We collected peripheral blood and analyzed the cells using flow cytometry after stimulation with mite antigens. Mite-specific Tregs and mite-specific Teffs were recognized by the expression of CD137 and CD154, respectively. Patients with AD had more Tregs than HCs; however, when focusing on a single antigen, the ratio of mite-specific Tregs/Teffs was lower in patients with AD than in HCs. Furthermore, the mite-specific Teffs in patients with AD were more likely to produce proinflammatory cytokines interleukin (IL)-4 and IL-13. This Teff-dominant imbalance is thought to be the cause of development of atopic status in patients with AD without immune tolerance." @default.
- W4377019567 created "2023-05-19" @default.
- W4377019567 creator A5007192124 @default.
- W4377019567 creator A5009334985 @default.
- W4377019567 creator A5029342620 @default.
- W4377019567 creator A5033739161 @default.
- W4377019567 creator A5040895870 @default.
- W4377019567 creator A5045037913 @default.
- W4377019567 creator A5051110759 @default.
- W4377019567 creator A5076824220 @default.
- W4377019567 creator A5080674641 @default.
- W4377019567 date "2023-07-01" @default.
- W4377019567 modified "2023-10-16" @default.
- W4377019567 title "Antigen-specific T cell balance reveals Why patients with atopic dermatitis fail to achieve immune tolerance" @default.
- W4377019567 cites W1529424687 @default.
- W4377019567 cites W1887030808 @default.
- W4377019567 cites W1956725346 @default.
- W4377019567 cites W1982898080 @default.
- W4377019567 cites W1998157143 @default.
- W4377019567 cites W2002288230 @default.
- W4377019567 cites W2006120701 @default.
- W4377019567 cites W2014208305 @default.
- W4377019567 cites W2028176002 @default.
- W4377019567 cites W2028567505 @default.
- W4377019567 cites W2052086128 @default.
- W4377019567 cites W2067263905 @default.
- W4377019567 cites W2067510223 @default.
- W4377019567 cites W2072753651 @default.
- W4377019567 cites W2077490433 @default.
- W4377019567 cites W2088772340 @default.
- W4377019567 cites W2116158190 @default.
- W4377019567 cites W2117359358 @default.
- W4377019567 cites W2117983771 @default.
- W4377019567 cites W2118630839 @default.
- W4377019567 cites W2123978534 @default.
- W4377019567 cites W2142327072 @default.
- W4377019567 cites W2145727904 @default.
- W4377019567 cites W2199672799 @default.
- W4377019567 cites W2214516135 @default.
- W4377019567 cites W2301691565 @default.
- W4377019567 cites W2315559373 @default.
- W4377019567 cites W2325674769 @default.
- W4377019567 cites W2515914179 @default.
- W4377019567 cites W2536035995 @default.
- W4377019567 cites W2597175831 @default.
- W4377019567 cites W2784010902 @default.
- W4377019567 cites W2786546201 @default.
- W4377019567 cites W2786669017 @default.
- W4377019567 cites W2884691736 @default.
- W4377019567 cites W2972485566 @default.
- W4377019567 cites W2981437222 @default.
- W4377019567 cites W2986480592 @default.
- W4377019567 cites W3091949070 @default.
- W4377019567 cites W3140327226 @default.
- W4377019567 cites W3179262370 @default.
- W4377019567 cites W3201772056 @default.
- W4377019567 cites W4220870254 @default.
- W4377019567 cites W4244585549 @default.
- W4377019567 cites W4280583598 @default.
- W4377019567 doi "https://doi.org/10.1016/j.clim.2023.109649" @default.
- W4377019567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37209805" @default.
- W4377019567 hasPublicationYear "2023" @default.
- W4377019567 type Work @default.
- W4377019567 citedByCount "0" @default.
- W4377019567 crossrefType "journal-article" @default.
- W4377019567 hasAuthorship W4377019567A5007192124 @default.
- W4377019567 hasAuthorship W4377019567A5009334985 @default.
- W4377019567 hasAuthorship W4377019567A5029342620 @default.
- W4377019567 hasAuthorship W4377019567A5033739161 @default.
- W4377019567 hasAuthorship W4377019567A5040895870 @default.
- W4377019567 hasAuthorship W4377019567A5045037913 @default.
- W4377019567 hasAuthorship W4377019567A5051110759 @default.
- W4377019567 hasAuthorship W4377019567A5076824220 @default.
- W4377019567 hasAuthorship W4377019567A5080674641 @default.
- W4377019567 hasConcept C147483822 @default.
- W4377019567 hasConcept C154317977 @default.
- W4377019567 hasConcept C164027704 @default.
- W4377019567 hasConcept C202751555 @default.
- W4377019567 hasConcept C203014093 @default.
- W4377019567 hasConcept C207480886 @default.
- W4377019567 hasConcept C2776090121 @default.
- W4377019567 hasConcept C2776914184 @default.
- W4377019567 hasConcept C2778166374 @default.
- W4377019567 hasConcept C2778329239 @default.
- W4377019567 hasConcept C2779234475 @default.
- W4377019567 hasConcept C2779711295 @default.
- W4377019567 hasConcept C2780510475 @default.
- W4377019567 hasConcept C39347974 @default.
- W4377019567 hasConcept C553184892 @default.
- W4377019567 hasConcept C55493867 @default.
- W4377019567 hasConcept C59822182 @default.
- W4377019567 hasConcept C71924100 @default.
- W4377019567 hasConcept C86803240 @default.
- W4377019567 hasConcept C8891405 @default.
- W4377019567 hasConceptScore W4377019567C147483822 @default.
- W4377019567 hasConceptScore W4377019567C154317977 @default.
- W4377019567 hasConceptScore W4377019567C164027704 @default.
- W4377019567 hasConceptScore W4377019567C202751555 @default.