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- W4377029306 abstract "Introduction Given the proportion of pregnant women with gestational hypertension or pre-eclampsia using an antidepressant we aimed to gain insight into the effects concerning for both mother and neonate especially on birth weight, APGAR score, and pregnancy duration. Study design Retrospective cohort study of women with hypertension disorders, whether or not using antidepressants. Main outcome measures: Birth weight, APGAR score, admittance to Obstetrical High Care unit (OHC) and or Neonatal Intensive Care Unit and pregnancy duration Results The use of antidepressants was associated with lower APGAR scores at 10 minutes, p= 0.008, OR = 2.298; 95% CI 1.255–4.273, compared to neonates from mothers without antidepressants. Women using antidepressants were more often admitted to the OHC (crude OR= 1.95; p=0.049; 95% CI 0.99–3.77). Multivariable logistic regression analysis revealed that thyroid disease and preterm ending of pregnancy contributed to the model, where use of antidepressants remained significant (OR=6.28; 95% CI 2.32–18.31). Conclusions Women with hypertension disorders during pregnancy and using antidepressants might have an increased risk for complications leading to OHC admission." @default.
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- W4377029306 date "2023-05-18" @default.
- W4377029306 modified "2023-09-30" @default.
- W4377029306 title "4 Risks associated with antidepressants in patients with hypertension during pregnancy: a retrospective cohort study" @default.
- W4377029306 doi "https://doi.org/10.1136/archdischild-2023-esdppp.4" @default.
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