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• W4377029951 abstract "We designed and synthesized novel 4-acetoxypentanamide derivatives of spliceostatin A, whose 4-acetoxypentenamide moiety is reduced (7), isomerized (8), or substituted with methyl at the α-position (9). The results of biological evaluation against AR-V7 and the docking analysis of each derivative suggest that the geometry of the 4-acetoxypentenamide moiety of spliceostatin A is important for its biological activity." @default.
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• W4377029951 date "2023-07-01" @default.
• W4377029951 modified "2023-10-16" @default.
• W4377029951 title "Design and synthesis of 4-acetoxypentanamide derivatives of spliceostatin A and their biological evaluation towards prostate cancer treatment" @default.
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• W4377029951 doi "https://doi.org/10.1016/j.bmcl.2023.129333" @default.
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