Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377041330> ?p ?o ?g. }
- W4377041330 endingPage "719" @default.
- W4377041330 startingPage "719" @default.
- W4377041330 abstract "Droplet digital PCR (ddPCR) recently has been shown to be a potential diagnostic tool for adults with bloodstream infections (BSIs); however, its application in children remains obscure. In this study, 76 blood samples of children with suspected BSIs were synchronously detected by traditional blood cultures (BCs) and ddPCRs. Our team validated the diagnostic performance of ddPCR including sensitivity, specificity, and positive and negative predictive values. The 76 pediatric patients from the hematology department (67.1%), the pediatric intensive care unit (PICU, 27.6%), and other departments (5.2%) were enrolled. The positive rate of ddPCR results was 47.9%, whereas that for BC was 6.6%. In addition, the time consumption of ddPCR was shorter, only for 4.7 ± 0.9 h, in comparison with the detection timing of BC (76.7 ± 10.4 h, p < 0.01). The levels of agreement and disagreement between BC and ddPCR were 96.1% and 4.2%, and the negative agreement reached 95.6%. The sensitivity of ddPCR was 100%, with corresponding specificities ranging from 95.3 to 100.0%. In addition, a total of nine viruses were identified by ddPCR. In China, the multiplexed ddPCR first could be a tool for the rapid and accurate diagnosis of children with suspected BSIs and can be an early indicator of the possibility of viraemia in children with immunosuppression." @default.
- W4377041330 created "2023-05-19" @default.
- W4377041330 creator A5018724340 @default.
- W4377041330 creator A5021699990 @default.
- W4377041330 creator A5025471145 @default.
- W4377041330 creator A5030968272 @default.
- W4377041330 creator A5045260806 @default.
- W4377041330 creator A5065275103 @default.
- W4377041330 creator A5069849278 @default.
- W4377041330 date "2023-05-16" @default.
- W4377041330 modified "2023-09-29" @default.
- W4377041330 title "Clinical Application of a Multiplex Droplet Digital PCR in the Rapid Diagnosis of Children with Suspected Bloodstream Infections" @default.
- W4377041330 cites W128189069 @default.
- W4377041330 cites W1483392047 @default.
- W4377041330 cites W1919435994 @default.
- W4377041330 cites W1984576168 @default.
- W4377041330 cites W1994176884 @default.
- W4377041330 cites W2004728218 @default.
- W4377041330 cites W2043445348 @default.
- W4377041330 cites W2076590961 @default.
- W4377041330 cites W2088547622 @default.
- W4377041330 cites W2103338644 @default.
- W4377041330 cites W2118352207 @default.
- W4377041330 cites W2128593286 @default.
- W4377041330 cites W2136323805 @default.
- W4377041330 cites W2143012846 @default.
- W4377041330 cites W2146935260 @default.
- W4377041330 cites W2167626887 @default.
- W4377041330 cites W2280404143 @default.
- W4377041330 cites W2286952948 @default.
- W4377041330 cites W2305612787 @default.
- W4377041330 cites W2327630244 @default.
- W4377041330 cites W2509442369 @default.
- W4377041330 cites W2575793503 @default.
- W4377041330 cites W2583810908 @default.
- W4377041330 cites W2761489767 @default.
- W4377041330 cites W2768590152 @default.
- W4377041330 cites W2788486606 @default.
- W4377041330 cites W2806906712 @default.
- W4377041330 cites W2809930572 @default.
- W4377041330 cites W2889641974 @default.
- W4377041330 cites W2946198733 @default.
- W4377041330 cites W2947820554 @default.
- W4377041330 cites W2958994975 @default.
- W4377041330 cites W2972360828 @default.
- W4377041330 cites W2974219676 @default.
- W4377041330 cites W2981437077 @default.
- W4377041330 cites W2995432985 @default.
- W4377041330 cites W2998853022 @default.
- W4377041330 cites W3000477794 @default.
- W4377041330 cites W3035801559 @default.
- W4377041330 cites W3096943828 @default.
- W4377041330 cites W3120727312 @default.
- W4377041330 cites W3127390171 @default.
- W4377041330 cites W3129122849 @default.
- W4377041330 cites W3131327775 @default.
- W4377041330 cites W3151221590 @default.
- W4377041330 cites W3161108915 @default.
- W4377041330 cites W3165247538 @default.
- W4377041330 cites W3177629744 @default.
- W4377041330 cites W3205526013 @default.
- W4377041330 cites W4200400849 @default.
- W4377041330 cites W4214821694 @default.
- W4377041330 cites W4220905115 @default.
- W4377041330 cites W4285082501 @default.
- W4377041330 cites W4290565908 @default.
- W4377041330 cites W4295980677 @default.
- W4377041330 cites W4300717331 @default.
- W4377041330 cites W4309609814 @default.
- W4377041330 cites W4313730628 @default.
- W4377041330 cites W4322728671 @default.
- W4377041330 doi "https://doi.org/10.3390/pathogens12050719" @default.
- W4377041330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37242389" @default.
- W4377041330 hasPublicationYear "2023" @default.
- W4377041330 type Work @default.
- W4377041330 citedByCount "2" @default.
- W4377041330 countsByYear W43770413302023 @default.
- W4377041330 crossrefType "journal-article" @default.
- W4377041330 hasAuthorship W4377041330A5018724340 @default.
- W4377041330 hasAuthorship W4377041330A5021699990 @default.
- W4377041330 hasAuthorship W4377041330A5025471145 @default.
- W4377041330 hasAuthorship W4377041330A5030968272 @default.
- W4377041330 hasAuthorship W4377041330A5045260806 @default.
- W4377041330 hasAuthorship W4377041330A5065275103 @default.
- W4377041330 hasAuthorship W4377041330A5069849278 @default.
- W4377041330 hasBestOaLocation W43770413301 @default.
- W4377041330 hasConcept C104317684 @default.
- W4377041330 hasConcept C126322002 @default.
- W4377041330 hasConcept C187212893 @default.
- W4377041330 hasConcept C194409129 @default.
- W4377041330 hasConcept C2781188995 @default.
- W4377041330 hasConcept C48126324 @default.
- W4377041330 hasConcept C49105822 @default.
- W4377041330 hasConcept C55493867 @default.
- W4377041330 hasConcept C60644358 @default.
- W4377041330 hasConcept C71924100 @default.
- W4377041330 hasConcept C86803240 @default.
- W4377041330 hasConceptScore W4377041330C104317684 @default.