FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377043976> ?p ?o ?g. }

• W4377043976 endingPage "2342" @default.
• W4377043976 startingPage "2342" @default.
• W4377043976 abstract "The important metabolic characteristics of cancer cells include increased fat production and changes in amino acid metabolism. Based on the category of tumor, tumor cells are capable of synthesizing as much as 95% of saturated and monounsaturated fatty acids through de novo synthesis, even in the presence of sufficient dietary lipid intake. This fat transformation starts early when cell cancerization and further spread along with the tumor cells grow more malignant. In addition, local catabolism of tryptophan, a common feature, can weaken anti-tumor immunity in primary tumor lesions and TDLN. Arginine catabolism is likewise related with the inhibition of anti-tumor immunity. Due to the crucial role of amino acids in tumor growth, increasing tryptophan along with arginine catabolism will promote tumor growth. However, immune cells also require amino acids to expand and distinguish into effector cells that can kill tumor cells. Therefore, it is necessary to have a deeper understanding of the metabolism of amino acids and fatty acids within cells. In this study, we established a method for the simultaneous analysis of 64 metabolites consisting of fatty acids and amino acids, covering biosynthesis of unsaturated fatty acids, aminoacyl-tRNA biosynthesis, and fatty acid biosynthesis using the Agilent GC-MS system. We selected linoleic acid, linolenic acid, sodium acetate, and sodium butyrate to treat H460 cells to validate the current method. The differential metabolites observed in the four fatty acid groups in comparison with the control group indicate the metabolic effects of various fatty acids on H460 cells. These differential metabolites could potentially become biomarkers for the early diagnosis of lung cancer." @default.
• W4377043976 created "2023-05-19" @default.
• W4377043976 creator A5010390436 @default.
• W4377043976 creator A5020707265 @default.
• W4377043976 creator A5025615349 @default.
• W4377043976 creator A5035729876 @default.
• W4377043976 creator A5047800210 @default.
• W4377043976 creator A5054429210 @default.
• W4377043976 creator A5075448214 @default.
• W4377043976 creator A5089374458 @default.
• W4377043976 date "2023-05-17" @default.
• W4377043976 modified "2023-10-07" @default.
• W4377043976 title "GC/MS-Based Analysis of Fatty Acids and Amino Acids in H460 Cells Treated with Short-Chain and Polyunsaturated Fatty Acids: A Highly Sensitive Approach" @default.
• W4377043976 cites W1975173686 @default.
• W4377043976 cites W1978495221 @default.
• W4377043976 cites W2014349355 @default.
• W4377043976 cites W2019095153 @default.
• W4377043976 cites W2024558044 @default.
• W4377043976 cites W2038639040 @default.
• W4377043976 cites W2042710537 @default.
• W4377043976 cites W2097637096 @default.
• W4377043976 cites W2131103345 @default.
• W4377043976 cites W2264411128 @default.
• W4377043976 cites W2335805754 @default.
• W4377043976 cites W2503851771 @default.
• W4377043976 cites W2791904618 @default.
• W4377043976 cites W2802429693 @default.
• W4377043976 cites W2807714941 @default.
• W4377043976 cites W2905076305 @default.
• W4377043976 cites W2911746882 @default.
• W4377043976 cites W2913095286 @default.
• W4377043976 cites W2940926088 @default.
• W4377043976 cites W2969363331 @default.
• W4377043976 cites W2972884213 @default.
• W4377043976 cites W3006025184 @default.
• W4377043976 cites W3035563103 @default.
• W4377043976 cites W3120949185 @default.
• W4377043976 cites W3134157209 @default.
• W4377043976 cites W3135169420 @default.
• W4377043976 cites W3158660301 @default.
• W4377043976 cites W3158890392 @default.
• W4377043976 cites W3159507532 @default.
• W4377043976 cites W4281861547 @default.
• W4377043976 cites W4323317258 @default.
• W4377043976 doi "https://doi.org/10.3390/nu15102342" @default.
• W4377043976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37242225" @default.
• W4377043976 hasPublicationYear "2023" @default.
• W4377043976 type Work @default.
• W4377043976 citedByCount "0" @default.
• W4377043976 crossrefType "journal-article" @default.
• W4377043976 hasAuthorship W4377043976A5010390436 @default.
• W4377043976 hasAuthorship W4377043976A5020707265 @default.
• W4377043976 hasAuthorship W4377043976A5025615349 @default.
• W4377043976 hasAuthorship W4377043976A5035729876 @default.
• W4377043976 hasAuthorship W4377043976A5047800210 @default.
• W4377043976 hasAuthorship W4377043976A5054429210 @default.
• W4377043976 hasAuthorship W4377043976A5075448214 @default.
• W4377043976 hasAuthorship W4377043976A5089374458 @default.
• W4377043976 hasBestOaLocation W43770439761 @default.
• W4377043976 hasConcept C104317684 @default.
• W4377043976 hasConcept C185592680 @default.
• W4377043976 hasConcept C19038510 @default.
• W4377043976 hasConcept C192989942 @default.
• W4377043976 hasConcept C2777468819 @default.
• W4377043976 hasConcept C515207424 @default.
• W4377043976 hasConcept C543025807 @default.
• W4377043976 hasConcept C553450214 @default.
• W4377043976 hasConcept C55493867 @default.
• W4377043976 hasConcept C62231903 @default.
• W4377043976 hasConcept C86803240 @default.
• W4377043976 hasConcept C96942376 @default.
• W4377043976 hasConceptScore W4377043976C104317684 @default.
• W4377043976 hasConceptScore W4377043976C185592680 @default.
• W4377043976 hasConceptScore W4377043976C19038510 @default.
• W4377043976 hasConceptScore W4377043976C192989942 @default.
• W4377043976 hasConceptScore W4377043976C2777468819 @default.
• W4377043976 hasConceptScore W4377043976C515207424 @default.
• W4377043976 hasConceptScore W4377043976C543025807 @default.
• W4377043976 hasConceptScore W4377043976C553450214 @default.
• W4377043976 hasConceptScore W4377043976C55493867 @default.
• W4377043976 hasConceptScore W4377043976C62231903 @default.
• W4377043976 hasConceptScore W4377043976C86803240 @default.
• W4377043976 hasConceptScore W4377043976C96942376 @default.
• W4377043976 hasFunder F4320321001 @default.
• W4377043976 hasIssue "10" @default.
• W4377043976 hasLocation W43770439761 @default.
• W4377043976 hasLocation W43770439762 @default.
• W4377043976 hasOpenAccess W4377043976 @default.
• W4377043976 hasPrimaryLocation W43770439761 @default.
• W4377043976 hasRelatedWork W111513954 @default.
• W4377043976 hasRelatedWork W1642498015 @default.
• W4377043976 hasRelatedWork W1927591950 @default.
• W4377043976 hasRelatedWork W2006699375 @default.
• W4377043976 hasRelatedWork W2045502634 @default.
• W4377043976 hasRelatedWork W2111206898 @default.
• W4377043976 hasRelatedWork W2123346024 @default.
• W4377043976 hasRelatedWork W2138736194 @default.
• W4377043976 hasRelatedWork W2497459222 @default.

• next