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- W4377090417 abstract "The thymoproteasome is a type of proteasome expressed specifically in thymic cortical epithelial cells. Thymoproteasome affects antigen processing of major histocompatibility complex (MHC)-I-associated peptides and optimizes positive selection of CD8+ T cells. However, it remains unanswered whether and how thymoproteasome-dependent MHC-I-associated self-peptides contribute to positive selection of cortical thymocytes. This short piece discusses the potential mechanisms of thymoproteasome contribution to positive selection of MHC-I-restricted CD8+ T cells." @default.
- W4377090417 created "2023-05-20" @default.
- W4377090417 creator A5086413249 @default.
- W4377090417 date "2023-08-01" @default.
- W4377090417 modified "2023-09-27" @default.
- W4377090417 title "The thymoproteasome in shaping the CD8+ T-cell repertoire" @default.
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- W4377090417 doi "https://doi.org/10.1016/j.coi.2023.102336" @default.
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