FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377103162> ?p ?o ?g. }

• W4377103162 endingPage "967" @default.
• W4377103162 startingPage "967" @default.
• W4377103162 abstract "Dedifferentiated liposarcoma of the deep soft tissue of the lower extremities is an infrequent finding. Myxoid liposarcoma is considered the most common soft tissue neoplasia arising in this anatomic region. Divergent differentiation usually occurs within well-differentiated liposarcoma and is exceedingly rare in a myxoid liposarcoma. We report a 32-year-old man who developed a dedifferentiated liposarcoma of the thigh on the background of a pre-existing myxoid liposarcoma. The gross examination of the surgical specimen showed a 11/7/2 cm tumour mass with solid tan-grey areas and focal myxoid degeneration. The microscopic examination revealed a malignant lipogenic proliferation, containing round cells with hyperchromatic nuclei and atypical lipoblasts, confined to the basophilic stroma with a myxoid aspect. Abrupt transition towards a hypercellular, non-lipogenic area consisting of highly pleomorphic spindle cells with atypical mitotic figures was also noted. Immunohistochemical staining was performed. Tumour cells in the lipogenic area were intensely positive for S100 and p16, and CD34 staining highlighted an arborizing capillary network. The dedifferentiated tumour areas showed positive MDM2 and CDK4 staining within neoplastic cells, with the Ki 67 proliferation marker expressed in approximately 10% of the cells. Wild-type TP53 protein expression pattern was documented. Thus, the diagnosis of a dedifferentiated liposarcoma was established. This paper aims to provide further knowledge about liposarcomas with divergent differentiation at peculiar locations, emphasizing the importance of histopathologic examination and immunohistochemical analysis for establishing the diagnosis and assessing the therapeutic response and prognosis of this condition." @default.
• W4377103162 created "2023-05-20" @default.
• W4377103162 creator A5016384745 @default.
• W4377103162 creator A5017398551 @default.
• W4377103162 creator A5024403229 @default.
• W4377103162 creator A5052926136 @default.
• W4377103162 creator A5055347132 @default.
• W4377103162 creator A5058931656 @default.
• W4377103162 creator A5081045437 @default.
• W4377103162 creator A5091982018 @default.
• W4377103162 creator A5091982019 @default.
• W4377103162 creator A5091982017 @default.
• W4377103162 date "2023-05-17" @default.
• W4377103162 modified "2023-10-17" @default.
• W4377103162 title "The Conundrum of Dedifferentiation in a Liposarcoma at a Peculiar Location: A Case Report and Literature Review" @default.
• W4377103162 cites W1501706240 @default.
• W4377103162 cites W1586740324 @default.
• W4377103162 cites W1669533272 @default.
• W4377103162 cites W1857700247 @default.
• W4377103162 cites W1967857594 @default.
• W4377103162 cites W2016879136 @default.
• W4377103162 cites W2079386541 @default.
• W4377103162 cites W2147350446 @default.
• W4377103162 cites W2156189308 @default.
• W4377103162 cites W218212025 @default.
• W4377103162 cites W2295168822 @default.
• W4377103162 cites W2331125208 @default.
• W4377103162 cites W2468285429 @default.
• W4377103162 cites W2499757144 @default.
• W4377103162 cites W2516552213 @default.
• W4377103162 cites W2520576659 @default.
• W4377103162 cites W2531209889 @default.
• W4377103162 cites W2557513832 @default.
• W4377103162 cites W2597005007 @default.
• W4377103162 cites W2726935839 @default.
• W4377103162 cites W2763452222 @default.
• W4377103162 cites W2772838698 @default.
• W4377103162 cites W2803795784 @default.
• W4377103162 cites W2891415253 @default.
• W4377103162 cites W2901895994 @default.
• W4377103162 cites W2913881486 @default.
• W4377103162 cites W2920631851 @default.
• W4377103162 cites W2937842093 @default.
• W4377103162 cites W2947102344 @default.
• W4377103162 cites W2972596397 @default.
• W4377103162 cites W2973019255 @default.
• W4377103162 cites W2979782206 @default.
• W4377103162 cites W2981626510 @default.
• W4377103162 cites W3004993880 @default.
• W4377103162 cites W3013386501 @default.
• W4377103162 cites W3015054752 @default.
• W4377103162 cites W3073970594 @default.
• W4377103162 cites W3094757080 @default.
• W4377103162 cites W3156007826 @default.
• W4377103162 cites W3179602933 @default.
• W4377103162 cites W3185271092 @default.
• W4377103162 cites W4206994267 @default.
• W4377103162 cites W4211125059 @default.
• W4377103162 doi "https://doi.org/10.3390/medicina59050967" @default.
• W4377103162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37241198" @default.
• W4377103162 hasPublicationYear "2023" @default.
• W4377103162 type Work @default.
• W4377103162 citedByCount "0" @default.
• W4377103162 crossrefType "journal-article" @default.
• W4377103162 hasAuthorship W4377103162A5016384745 @default.
• W4377103162 hasAuthorship W4377103162A5017398551 @default.
• W4377103162 hasAuthorship W4377103162A5024403229 @default.
• W4377103162 hasAuthorship W4377103162A5052926136 @default.
• W4377103162 hasAuthorship W4377103162A5055347132 @default.
• W4377103162 hasAuthorship W4377103162A5058931656 @default.
• W4377103162 hasAuthorship W4377103162A5081045437 @default.
• W4377103162 hasAuthorship W4377103162A5091982017 @default.
• W4377103162 hasAuthorship W4377103162A5091982018 @default.
• W4377103162 hasAuthorship W4377103162A5091982019 @default.
• W4377103162 hasBestOaLocation W43771031621 @default.
• W4377103162 hasConcept C10205521 @default.
• W4377103162 hasConcept C105702510 @default.
• W4377103162 hasConcept C136948725 @default.
• W4377103162 hasConcept C142724271 @default.
• W4377103162 hasConcept C19210678 @default.
• W4377103162 hasConcept C204232928 @default.
• W4377103162 hasConcept C2778256501 @default.
• W4377103162 hasConcept C2779568860 @default.
• W4377103162 hasConcept C2781225692 @default.
• W4377103162 hasConcept C28328180 @default.
• W4377103162 hasConcept C2910450773 @default.
• W4377103162 hasConcept C71924100 @default.
• W4377103162 hasConcept C86803240 @default.
• W4377103162 hasConcept C95444343 @default.
• W4377103162 hasConceptScore W4377103162C10205521 @default.
• W4377103162 hasConceptScore W4377103162C105702510 @default.
• W4377103162 hasConceptScore W4377103162C136948725 @default.
• W4377103162 hasConceptScore W4377103162C142724271 @default.
• W4377103162 hasConceptScore W4377103162C19210678 @default.
• W4377103162 hasConceptScore W4377103162C204232928 @default.
• W4377103162 hasConceptScore W4377103162C2778256501 @default.
• W4377103162 hasConceptScore W4377103162C2779568860 @default.
• W4377103162 hasConceptScore W4377103162C2781225692 @default.

• next