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• W4377103532 endingPage "100672" @default.
• W4377103532 startingPage "100672" @default.
• W4377103532 abstract "Over the past three decades, nanoscience has offered a unique solution for reducing the systemic toxicity of chemotherapy drugs and for increasing drug therapeutic efficiency. However, the poor accumulation and pharmacokinetics of nanoparticles are some of the key reasons for their slow translation into the clinic. The is intimately linked to the non-biological nature of nanoparticles and the aberrant features of solid cancer, which together significantly compromise nanoparticle delivery. New findings on the unique properties of tumors and their interactions with nanoparticles and the human body suggest that, contrary to what was long-believed, tumor features may be more mirage than miracle, as the enhanced permeability and retention based efficacy is estimated to be as low as 1%. In this review, we highlight the current barriers and available solutions to pave the way for approved nanoformulations. Furthermore, we aim to discuss the main solutions to solve inefficient drug delivery with the use of nanobioengineering of nanocarriers and the tumor environment. Finally, we will discuss the suggested strategies to overcome two or more biological barriers with one nanocarrier. The variety of design formats, applications and implications of each of these methods will also be evaluated." @default.
• W4377103532 created "2023-05-20" @default.
• W4377103532 creator A5000416465 @default.
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• W4377103532 date "2023-06-01" @default.
• W4377103532 modified "2023-10-01" @default.
• W4377103532 title "Multifunctional nanostructures: Intelligent design to overcome biological barriers" @default.
• W4377103532 cites W1156966783 @default.
• W4377103532 cites W1526894457 @default.
• W4377103532 cites W1725865716 @default.
• W4377103532 cites W1914131546 @default.
• W4377103532 cites W1962872293 @default.
• W4377103532 cites W1976815031 @default.
• W4377103532 cites W1981280267 @default.
• W4377103532 cites W2009676793 @default.
• W4377103532 cites W2043042951 @default.
• W4377103532 cites W2050698575 @default.
• W4377103532 cites W2059223510 @default.
• W4377103532 cites W2066404267 @default.
• W4377103532 cites W2067796149 @default.
• W4377103532 cites W2075084694 @default.
• W4377103532 cites W2122751535 @default.
• W4377103532 cites W2126163864 @default.
• W4377103532 cites W2128668100 @default.
• W4377103532 cites W2134902598 @default.
• W4377103532 cites W2145865499 @default.
• W4377103532 cites W2156587383 @default.
• W4377103532 cites W2170315635 @default.
• W4377103532 cites W2177773825 @default.
• W4377103532 cites W2197203468 @default.
• W4377103532 cites W2236945153 @default.
• W4377103532 cites W2284550715 @default.
• W4377103532 cites W2298595881 @default.
• W4377103532 cites W2312624944 @default.
• W4377103532 cites W2322861634 @default.
• W4377103532 cites W2324440130 @default.
• W4377103532 cites W2326188833 @default.
• W4377103532 cites W2335076883 @default.
• W4377103532 cites W2346043912 @default.
• W4377103532 cites W2409932367 @default.
• W4377103532 cites W2467367227 @default.
• W4377103532 cites W2469134118 @default.
• W4377103532 cites W2515051096 @default.
• W4377103532 cites W2518509288 @default.
• W4377103532 cites W2549976854 @default.
• W4377103532 cites W2555200685 @default.
• W4377103532 cites W2555883270 @default.
• W4377103532 cites W2556868315 @default.
• W4377103532 cites W2562913827 @default.
• W4377103532 cites W2564665116 @default.
• W4377103532 cites W2567676221 @default.
• W4377103532 cites W2568972635 @default.
• W4377103532 cites W2569530200 @default.
• W4377103532 cites W2584750294 @default.
• W4377103532 cites W2586637063 @default.
• W4377103532 cites W2587823650 @default.
• W4377103532 cites W2589961504 @default.
• W4377103532 cites W2594354610 @default.
• W4377103532 cites W2606222589 @default.
• W4377103532 cites W2612358593 @default.
• W4377103532 cites W2612903966 @default.
• W4377103532 cites W2728722006 @default.
• W4377103532 cites W2737699620 @default.
• W4377103532 cites W2740408601 @default.
• W4377103532 cites W2742885310 @default.
• W4377103532 cites W2748893263 @default.
• W4377103532 cites W2757272801 @default.
• W4377103532 cites W2765158737 @default.
• W4377103532 cites W2765284359 @default.
• W4377103532 cites W2767285576 @default.
• W4377103532 cites W2767878232 @default.
• W4377103532 cites W2769225534 @default.
• W4377103532 cites W2771808227 @default.
• W4377103532 cites W2772572314 @default.
• W4377103532 cites W2776345905 @default.
• W4377103532 cites W2777639606 @default.
• W4377103532 cites W2782175732 @default.
• W4377103532 cites W2789599622 @default.
• W4377103532 cites W2790258190 @default.
• W4377103532 cites W2790708193 @default.
• W4377103532 cites W2793869682 @default.
• W4377103532 cites W2795161016 @default.
• W4377103532 cites W2799935755 @default.
• W4377103532 cites W2800310789 @default.
• W4377103532 cites W2803273878 @default.
• W4377103532 cites W2804797062 @default.
• W4377103532 cites W2807815519 @default.

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