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- W4377103679 abstract "A subset of NSTEMI patients have culprit artery occlusion aka occlusion myocardial infarction (OMI). We aimed to identify this subset of patients with OMI, and the impact of revascularization timing on their cardiovascular (CV) outcomes. This is a retrospective study. Patients presenting with NSTEMI who underwent cardiac catheterization between January 2017 and December 2020 were identified, and followed for the later of 5 years or time of conclusion of this study. OMI was defined as culprit artery stenosis of > 90% with TIMI flow < 3. Cardiac catheterization > 24 hours (from the first elevated troponin) was termed as delayed. Primary endpoint was all cause mortality, CV death, recurrent MI, stroke and heart failure at 30 days. Secondary end points were CV death and all-cause mortality at 1 and 5 years. A total of 488 NSTEMI patients were identified, and 105 (21%) satisfied the criteria for OMI. Baseline characteristics were comparable among the OMI and Non-OMI (NOMI) group. Among the patients with delayed catheterisation (N=270), 30 day mortality was higher in the OMI group when compared to NOMI (P=0.04). Of the OMI patients, all-cause mortality at 30 days, 1 and 5 years was higher for those with delayed catheterization versus those with an early intervention (P<0.05). Our study identified 21% of NSTEMI patients to have OMI. Of these 48% had a 100% occlusion of the culprit artery. Patients with delayed catheterization had worse outcomes when compared to patients who received early intervention. This effect was more pronounced in patients with OMI. All-cause mortality at 1 and 5 years was higher in the OMI patients who had a delayed intervention, thus representing a high risk group. Future studies should be aimed to identify this high risk NSTEMI patients who would benefit from early revascularization." @default.
- W4377103679 created "2023-05-20" @default.
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- W4377103679 date "2023-05-01" @default.
- W4377103679 modified "2023-10-18" @default.
- W4377103679 title "A-35 | Is it Time for a Paradigm Shift Towards Occlusion Myocardial Infarction?" @default.
- W4377103679 doi "https://doi.org/10.1016/j.jscai.2023.100699" @default.
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