FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377104294> ?p ?o ?g. }

• W4377104294 endingPage "2622" @default.
• W4377104294 startingPage "2619" @default.
• W4377104294 abstract "Retinal dysfunction is the most common cause of vision loss in several retinal disorders. It has been estimated a great increase in these pathologies that are becoming more globally widespread and numerous over time, also supported by the life expectancy increment. Among different types of retinopathies, we can account some that share causes, symptoms, and treatment including diabetic retinopathy, age-related macular degeneration, glaucoma, and retinitis pigmentosa. Molecular changes, environmental factors, and genetic predisposition might be some of the main causes that drive retinal tissue to chronic inflammation and neurodegeneration in these retinopathies. The treatments available on the market contain compounds that efficiently ameliorate some of the important clinical features of these pathologies like stabilization of the intraocular pressure, reduction of eye inflammation, control of eye oxidative stress which are considered the major molecular mechanisms related to retinal dysfunction. Indeed, the most commonly used drugs are anti-inflammatories, such as corticosteroids, antioxidant, hypotonic molecules and natural neuroprotective compounds. Unfortunately, these drugs, which are fundamental to treating disease symptoms, are not capable to cure the pathologies and so they are not life-changing for patients. This review provided an overview of current treatments on the market, but more interestingly, wants to be a quick window on the new treatments that are now in clinical trials. Additionally, it has been here highlighted that the recent technical enhancement of the investigation methods to identify the various retinopathies causes might be used as a sort of precise medicine approach to tailor the identification of molecular pathways involved and potentially study a dedicated treatment for each patient. This approach includes the use of cutting-edge technologies like gene therapy and metabolomics." @default.
• W4377104294 created "2023-05-20" @default.
• W4377104294 creator A5029321754 @default.
• W4377104294 creator A5029889770 @default.
• W4377104294 creator A5081505316 @default.
• W4377104294 date "2023-04-10" @default.
• W4377104294 modified "2023-09-25" @default.
• W4377104294 title "Retinoprotective compounds, current efficacy, and future prospective" @default.
• W4377104294 cites W1995576014 @default.
• W4377104294 cites W2020401974 @default.
• W4377104294 cites W2097058003 @default.
• W4377104294 cites W2790218443 @default.
• W4377104294 cites W2791041549 @default.
• W4377104294 cites W2795630734 @default.
• W4377104294 cites W2895138297 @default.
• W4377104294 cites W2955477655 @default.
• W4377104294 cites W2982221081 @default.
• W4377104294 cites W2994910316 @default.
• W4377104294 cites W3003579022 @default.
• W4377104294 cites W3012959117 @default.
• W4377104294 cites W3033555223 @default.
• W4377104294 cites W3049295013 @default.
• W4377104294 cites W3104034748 @default.
• W4377104294 cites W3110175334 @default.
• W4377104294 cites W3124724358 @default.
• W4377104294 cites W3134802680 @default.
• W4377104294 cites W3139365097 @default.
• W4377104294 cites W3155009410 @default.
• W4377104294 cites W3171993855 @default.
• W4377104294 cites W3184631333 @default.
• W4377104294 cites W3199484775 @default.
• W4377104294 cites W3200707411 @default.
• W4377104294 cites W3200751431 @default.
• W4377104294 cites W3200803057 @default.
• W4377104294 cites W3212889913 @default.
• W4377104294 cites W3215448180 @default.
• W4377104294 cites W4205817815 @default.
• W4377104294 cites W4220670350 @default.
• W4377104294 cites W4280492686 @default.
• W4377104294 cites W4280576555 @default.
• W4377104294 cites W4281721457 @default.
• W4377104294 cites W4285090420 @default.
• W4377104294 cites W4286238533 @default.
• W4377104294 cites W4286434280 @default.
• W4377104294 cites W4288694044 @default.
• W4377104294 cites W4296720485 @default.
• W4377104294 cites W4306248787 @default.
• W4377104294 cites W4307639211 @default.
• W4377104294 doi "https://doi.org/10.4103/1673-5374.373662" @default.
• W4377104294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37449599" @default.
• W4377104294 hasPublicationYear "2023" @default.
• W4377104294 type Work @default.
• W4377104294 citedByCount "0" @default.
• W4377104294 crossrefType "journal-article" @default.
• W4377104294 hasAuthorship W4377104294A5029321754 @default.
• W4377104294 hasAuthorship W4377104294A5029889770 @default.
• W4377104294 hasAuthorship W4377104294A5081505316 @default.
• W4377104294 hasBestOaLocation W43771042941 @default.
• W4377104294 hasConcept C118487528 @default.
• W4377104294 hasConcept C134018914 @default.
• W4377104294 hasConcept C142724271 @default.
• W4377104294 hasConcept C169760540 @default.
• W4377104294 hasConcept C177713679 @default.
• W4377104294 hasConcept C25498285 @default.
• W4377104294 hasConcept C2776403814 @default.
• W4377104294 hasConcept C2776925932 @default.
• W4377104294 hasConcept C2778527774 @default.
• W4377104294 hasConcept C2779134260 @default.
• W4377104294 hasConcept C2779829184 @default.
• W4377104294 hasConcept C2780827179 @default.
• W4377104294 hasConcept C2781114197 @default.
• W4377104294 hasConcept C535046627 @default.
• W4377104294 hasConcept C555293320 @default.
• W4377104294 hasConcept C60644358 @default.
• W4377104294 hasConcept C71924100 @default.
• W4377104294 hasConcept C86803240 @default.
• W4377104294 hasConcept C98274493 @default.
• W4377104294 hasConceptScore W4377104294C118487528 @default.
• W4377104294 hasConceptScore W4377104294C134018914 @default.
• W4377104294 hasConceptScore W4377104294C142724271 @default.
• W4377104294 hasConceptScore W4377104294C169760540 @default.
• W4377104294 hasConceptScore W4377104294C177713679 @default.
• W4377104294 hasConceptScore W4377104294C25498285 @default.
• W4377104294 hasConceptScore W4377104294C2776403814 @default.
• W4377104294 hasConceptScore W4377104294C2776925932 @default.
• W4377104294 hasConceptScore W4377104294C2778527774 @default.
• W4377104294 hasConceptScore W4377104294C2779134260 @default.
• W4377104294 hasConceptScore W4377104294C2779829184 @default.
• W4377104294 hasConceptScore W4377104294C2780827179 @default.
• W4377104294 hasConceptScore W4377104294C2781114197 @default.
• W4377104294 hasConceptScore W4377104294C535046627 @default.
• W4377104294 hasConceptScore W4377104294C555293320 @default.
• W4377104294 hasConceptScore W4377104294C60644358 @default.
• W4377104294 hasConceptScore W4377104294C71924100 @default.
• W4377104294 hasConceptScore W4377104294C86803240 @default.
• W4377104294 hasConceptScore W4377104294C98274493 @default.
• W4377104294 hasIssue "12" @default.
• W4377104294 hasLocation W43771042941 @default.

• next