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- W4377107891 abstract "Pruritus is one of the most debilitating symptoms for patients with epidermolysis bullosa (EB). This study aimed to assess the burden of itch and to address its dimensions across patients with EB. Forty-six patients with EB were recruited from the Saudi EB registry to participate. All participants completed the Leuven Itch Scale. The sample included 5 patients with EB simplex (EBS), 3 with junctional EB (JEB), 34 with dystrophic EB (DEB), and 4 patients had unknown type. Overall, 97.8% patients reported itch. In patients with itch, 73.3% reported that it was often or always present, longer than 2 h Itch episodes was reported by JEB (66.7%) and recessive DEB (RDEB) (3.2%). Itch, in all its dimensions, was worst in patients with JEB and DEB than EBS. Itch occurred mostly in a hot environment (80%), when sweating (71.1%), in healing wounds (40%), and during dressing change (35.6%) whereas cold environment resulted in itch in only (2.2%). The burden of pruritus increased with increasing age. This study highlights a challenging area in EB care with a need for specific treatments." @default.
- W4377107891 created "2023-05-20" @default.
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- W4377107891 date "2023-05-18" @default.
- W4377107891 modified "2023-09-30" @default.
- W4377107891 title "Measuring the impact of pruritus on epidermolysis bullosa patients: evaluation using an itch-specific instrument" @default.
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- W4377107891 doi "https://doi.org/10.4081/dr.2023.9700" @default.
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