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- W4377121488 abstract "Abstract Alzheimer’s disease (AD) is an age-related neurodegenerative disease that affects over 6 million adults each year. As individuals age, their cells do not repair themselves which leads to proliferation arrest known as senescence. In the nervous system, astrocyte senescence has been associated with neuroinflammation and other AD processes. Thus, studying senescence may be a unique approach to understanding AD pathology. This study looks at the correlation between SCN9A, a novel gene target, and AD. Results suggest SCN9A may be a potential diagnostic marker for AD. A model was created with an 80%+ accuracy rate in predicting AD. Overall, this study suggests SCN9A plays a large role in neurodegeneration and treating AD." @default.
- W4377121488 created "2023-05-20" @default.
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- W4377121488 date "2023-05-20" @default.
- W4377121488 modified "2023-09-27" @default.
- W4377121488 title "<i>SCN9A</i>: Proposal of Voltage-Gated Ion Channels as a Novel Diagnostic Marker for Alzheimer’s Disease" @default.
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- W4377121488 doi "https://doi.org/10.1101/2023.05.18.23289925" @default.
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