FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377261306> ?p ?o ?g. }

• W4377261306 endingPage "104980" @default.
• W4377261306 startingPage "104980" @default.
• W4377261306 abstract "Natural peptides (NPs) are ubiquitous throughout the organism with diversified structures and wide dynamic concentration range, which leads to serious challenge for their comprehensive analysis. Herein, a pseudotargeted peptidomics strategy based on dynamic multiple reaction monitoring (DMRM) with high-throughput data acquisition and accurate quantification was established. Specifically, an in-house software Pep-MRMer was developed for extraction of ions information of peptides, followed by de-redundancy and fusion to construct a transition list. Additionally, retention time (RT) calibration method was optimized by using high content components for effective transference of ion pairs between different detection conditions (e.g., instruments, chromatographic gradients). This strategy was applied for profiling NPs and screening signature peptides for species authentication of Pheretima, a multi-source animal-derived drug widely used in Asian countries. In all, a total of 3307 peptides had excellent quantitative detection after transference. Subsequently, nine signature peptides with extraordinary specificity were screened, identified, and confirmed by comparing with the synthetic standards. Ultimately, a 10 min specific chromatogram based on signature peptides was developed, which realized rapid and accurate identification of Pheretima. Taken together, this research provides a robust strategy for species discrimination of animal-derived drugs without adequate quality control measures." @default.
• W4377261306 created "2023-05-23" @default.
• W4377261306 creator A5006173892 @default.
• W4377261306 creator A5012244262 @default.
• W4377261306 creator A5015236696 @default.
• W4377261306 creator A5016143963 @default.
• W4377261306 creator A5023005997 @default.
• W4377261306 creator A5041384759 @default.
• W4377261306 creator A5048502490 @default.
• W4377261306 creator A5052254951 @default.
• W4377261306 creator A5056834769 @default.
• W4377261306 creator A5068442608 @default.
• W4377261306 creator A5071216962 @default.
• W4377261306 creator A5083639590 @default.
• W4377261306 creator A5090494061 @default.
• W4377261306 date "2023-08-01" @default.
• W4377261306 modified "2023-10-04" @default.
• W4377261306 title "A pseudotargeted peptidomics strategy for screening natural signature peptides in animal-derived drugs: Taking Pheretima as a case" @default.
• W4377261306 cites W1989833877 @default.
• W4377261306 cites W1995005137 @default.
• W4377261306 cites W2004813038 @default.
• W4377261306 cites W2026433130 @default.
• W4377261306 cites W2054602599 @default.
• W4377261306 cites W2068268280 @default.
• W4377261306 cites W2073401456 @default.
• W4377261306 cites W2081465448 @default.
• W4377261306 cites W2092328303 @default.
• W4377261306 cites W2125269560 @default.
• W4377261306 cites W2156344403 @default.
• W4377261306 cites W2255019206 @default.
• W4377261306 cites W2353526782 @default.
• W4377261306 cites W2414717690 @default.
• W4377261306 cites W2785757836 @default.
• W4377261306 cites W2806559730 @default.
• W4377261306 cites W2945669687 @default.
• W4377261306 cites W3001463242 @default.
• W4377261306 cites W3014603907 @default.
• W4377261306 cites W3037865744 @default.
• W4377261306 cites W3135166985 @default.
• W4377261306 cites W3164442488 @default.
• W4377261306 cites W3183927913 @default.
• W4377261306 cites W3193507622 @default.
• W4377261306 cites W3197629547 @default.
• W4377261306 cites W3203456873 @default.
• W4377261306 cites W4200191868 @default.
• W4377261306 cites W4213245418 @default.
• W4377261306 doi "https://doi.org/10.1016/j.arabjc.2023.104980" @default.
• W4377261306 hasPublicationYear "2023" @default.
• W4377261306 type Work @default.
• W4377261306 citedByCount "1" @default.
• W4377261306 crossrefType "journal-article" @default.
• W4377261306 hasAuthorship W4377261306A5006173892 @default.
• W4377261306 hasAuthorship W4377261306A5012244262 @default.
• W4377261306 hasAuthorship W4377261306A5015236696 @default.
• W4377261306 hasAuthorship W4377261306A5016143963 @default.
• W4377261306 hasAuthorship W4377261306A5023005997 @default.
• W4377261306 hasAuthorship W4377261306A5041384759 @default.
• W4377261306 hasAuthorship W4377261306A5048502490 @default.
• W4377261306 hasAuthorship W4377261306A5052254951 @default.
• W4377261306 hasAuthorship W4377261306A5056834769 @default.
• W4377261306 hasAuthorship W4377261306A5068442608 @default.
• W4377261306 hasAuthorship W4377261306A5071216962 @default.
• W4377261306 hasAuthorship W4377261306A5083639590 @default.
• W4377261306 hasAuthorship W4377261306A5090494061 @default.
• W4377261306 hasBestOaLocation W43772613061 @default.
• W4377261306 hasConcept C124101348 @default.
• W4377261306 hasConcept C185592680 @default.
• W4377261306 hasConcept C186060115 @default.
• W4377261306 hasConcept C21951064 @default.
• W4377261306 hasConcept C41008148 @default.
• W4377261306 hasConcept C43617362 @default.
• W4377261306 hasConcept C70721500 @default.
• W4377261306 hasConcept C86803240 @default.
• W4377261306 hasConceptScore W4377261306C124101348 @default.
• W4377261306 hasConceptScore W4377261306C185592680 @default.
• W4377261306 hasConceptScore W4377261306C186060115 @default.
• W4377261306 hasConceptScore W4377261306C21951064 @default.
• W4377261306 hasConceptScore W4377261306C41008148 @default.
• W4377261306 hasConceptScore W4377261306C43617362 @default.
• W4377261306 hasConceptScore W4377261306C70721500 @default.
• W4377261306 hasConceptScore W4377261306C86803240 @default.
• W4377261306 hasIssue "8" @default.
• W4377261306 hasLocation W43772613061 @default.
• W4377261306 hasOpenAccess W4377261306 @default.
• W4377261306 hasPrimaryLocation W43772613061 @default.
• W4377261306 hasRelatedWork W1814206567 @default.
• W4377261306 hasRelatedWork W1975728616 @default.
• W4377261306 hasRelatedWork W2041719513 @default.
• W4377261306 hasRelatedWork W2044634666 @default.
• W4377261306 hasRelatedWork W2049874093 @default.
• W4377261306 hasRelatedWork W2072777769 @default.
• W4377261306 hasRelatedWork W2330215216 @default.
• W4377261306 hasRelatedWork W2899084033 @default.
• W4377261306 hasRelatedWork W2949431091 @default.
• W4377261306 hasRelatedWork W2778153218 @default.
• W4377261306 hasVolume "16" @default.
• W4377261306 isParatext "false" @default.
• W4377261306 isRetracted "false" @default.

• next