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• W4377291403 abstract "Muscle wasting is a consequence of physiological changes or a pathology characterized by increased catabolic activity that leads to progressive loss of skeletal muscle mass and strength. Numerous diseases, including cancer, organ failure, infection, and aging-associated diseases, are associated with muscle wasting. Cancer cachexia is a multifactorial syndrome characterized by loss of skeletal muscle mass, with or without the loss of fat mass, resulting in functional impairment and reduced quality of life. It is caused by the upregulation of systemic inflammation and catabolic stimuli, leading to inhibition of protein synthesis and enhancement of muscle catabolism. Here, we summarize the complex molecular networks that regulate muscle mass and function. Moreover, we describe complex multi-organ roles in cancer cachexia. Although cachexia is one of the main causes of cancer-related deaths, there are still no approved drugs for cancer cachexia. Thus, we compiled recent ongoing pre-clinical and clinical trials and further discussed potential therapeutic approaches for cancer cachexia." @default.
• W4377291403 created "2023-05-23" @default.
• W4377291403 creator A5005523440 @default.
• W4377291403 creator A5010439787 @default.
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• W4377291403 creator A5060258160 @default.
• W4377291403 creator A5065358482 @default.
• W4377291403 creator A5084941334 @default.
• W4377291403 creator A5091129221 @default.
• W4377291403 date "2023-05-22" @default.
• W4377291403 modified "2023-10-14" @default.
• W4377291403 title "Cancer cachexia: molecular mechanisms and treatment strategies" @default.
• W4377291403 cites W1488497469 @default.
• W4377291403 cites W1490028331 @default.
• W4377291403 cites W1497753108 @default.
• W4377291403 cites W1534582737 @default.
• W4377291403 cites W1564746483 @default.
• W4377291403 cites W1833512305 @default.
• W4377291403 cites W1870686894 @default.
• W4377291403 cites W1904342372 @default.
• W4377291403 cites W1910033896 @default.
• W4377291403 cites W1929299477 @default.
• W4377291403 cites W1938485232 @default.
• W4377291403 cites W1960861445 @default.
• W4377291403 cites W1965041525 @default.
• W4377291403 cites W1966206741 @default.
• W4377291403 cites W1966350956 @default.
• W4377291403 cites W1966920013 @default.
• W4377291403 cites W1968272322 @default.
• W4377291403 cites W1969373094 @default.
• W4377291403 cites W1969583687 @default.
• W4377291403 cites W1973533356 @default.
• W4377291403 cites W1973767788 @default.
• W4377291403 cites W1975913194 @default.
• W4377291403 cites W1979298497 @default.
• W4377291403 cites W1981025527 @default.
• W4377291403 cites W1983411014 @default.
• W4377291403 cites W1983660080 @default.
• W4377291403 cites W1985257308 @default.
• W4377291403 cites W1985534077 @default.
• W4377291403 cites W1987892987 @default.
• W4377291403 cites W1990125065 @default.
• W4377291403 cites W1990911170 @default.
• W4377291403 cites W1994774256 @default.
• W4377291403 cites W1996416219 @default.
• W4377291403 cites W1997014674 @default.
• W4377291403 cites W1997613626 @default.
• W4377291403 cites W2000066959 @default.
• W4377291403 cites W2002461978 @default.
• W4377291403 cites W2005933661 @default.
• W4377291403 cites W2006856254 @default.
• W4377291403 cites W2011226735 @default.
• W4377291403 cites W2011567765 @default.
• W4377291403 cites W2012577947 @default.
• W4377291403 cites W2014786409 @default.
• W4377291403 cites W2016815316 @default.
• W4377291403 cites W2018988532 @default.
• W4377291403 cites W2020213864 @default.
• W4377291403 cites W2020950789 @default.
• W4377291403 cites W2025192214 @default.
• W4377291403 cites W2027328996 @default.
• W4377291403 cites W2028043263 @default.
• W4377291403 cites W2028355250 @default.
• W4377291403 cites W2030562392 @default.
• W4377291403 cites W2031204178 @default.
• W4377291403 cites W2031411519 @default.
• W4377291403 cites W2032110122 @default.
• W4377291403 cites W2033924360 @default.
• W4377291403 cites W2034127653 @default.
• W4377291403 cites W2035555824 @default.
• W4377291403 cites W2035826810 @default.
• W4377291403 cites W2036787961 @default.
• W4377291403 cites W2037370931 @default.
• W4377291403 cites W2038469310 @default.
• W4377291403 cites W2038754320 @default.
• W4377291403 cites W2039590913 @default.
• W4377291403 cites W2039884049 @default.
• W4377291403 cites W2042604587 @default.
• W4377291403 cites W2042873218 @default.
• W4377291403 cites W2045762097 @default.
• W4377291403 cites W2049793957 @default.
• W4377291403 cites W2049946444 @default.
• W4377291403 cites W2050592095 @default.
• W4377291403 cites W2052712443 @default.
• W4377291403 cites W2053079324 @default.
• W4377291403 cites W2054138699 @default.
• W4377291403 cites W2054276958 @default.
• W4377291403 cites W2054950088 @default.
• W4377291403 cites W2056752733 @default.
• W4377291403 cites W2057518657 @default.
• W4377291403 cites W2059762067 @default.
• W4377291403 cites W2059771393 @default.
• W4377291403 cites W2060129186 @default.
• W4377291403 cites W2060137305 @default.
• W4377291403 cites W2061496437 @default.
• W4377291403 cites W2062360233 @default.
• W4377291403 cites W2066227828 @default.
• W4377291403 cites W2067161281 @default.
• W4377291403 cites W2067680253 @default.

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