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- W4377832449 abstract "Telomere length (TL) at birth is considered a potential biomarker for lifelong health. Although maternal sleep disturbance has been linked to a series of adverse pregnancy outcomes, evidence on the effect of maternal sleep on newborn TL remains scarce. Therefore, we aim to investigate the association of maternal sleep duration and sleep quality with newborn TL.A total of 742 mother-newborn pairs were recruited from Wuhan Children’s Hospital between November 2013 and March 2015. Cord blood TL was measured using real-time quantitative polymerase chain reaction. Maternal sleep duration and quality during late pregnancy were obtained via questionnaires. Multivariate linear regression models were used to estimate the effects of maternal sleep duration and sleep quality on newborn TL.A total of 742 maternal-newborn pairs were included in the analyses. Mothers sleeping ≥10 hours had a 9.30% (95% CI: 2.09%, 15.99%) shorter newborn TL than those sleeping 7-<9 hours. However, the association in mothers with short sleep duration (<7 hours) did not reach statistical significance. Compared to mothers with good sleep quality, those with poor sleep quality had a 9.91% (95% CI: 4.06%, 15.40%) shorter newborn TL. We observed a joint effect of sleep duration and sleep quality on newborn telomere shortening. Women with sleep duration ≥10 hours and poor sleep quality were most likely to have newborns with short TL (percent change:−19.66%, 95% CI: −28.42, −9.84%).Long sleep duration and poor sleep quality during late pregnancy were associated with shorter newborn TL." @default.
- W4377832449 created "2023-05-24" @default.
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- W4377832449 date "2023-08-01" @default.
- W4377832449 modified "2023-10-11" @default.
- W4377832449 title "Letter to the Editor on racial disparities in engagement with digital CBT-I among pregnant women" @default.
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- W4377832449 doi "https://doi.org/10.1016/j.sleh.2023.02.009" @default.
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