FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377940282> ?p ?o ?g. }

• W4377940282 endingPage "348" @default.
• W4377940282 startingPage "340" @default.
• W4377940282 abstract "Transsphenoidal surgery for non-functioning pituitary adenomas (NFPAs) can alter pituitary function. We assessed the rates of improvement and deterioration of pituitary function by axis and searched for predictive factors of these outcomes.We reviewed consecutive medical files from patients having had transsphenoidal surgery for NFPA between 2004 and 2018. Pituitary functions and MRI imaging were analyzed prior and after surgery. The occurrence of recovery and new deficit were documented per axis. Prognostic factors of hormonal recovery and new deficits were searched.Among 137 patients analyzed, median tumor size of the NFPA was 24.8 mm and 58.4% of patients presented visual impairment. Before surgery, 91 patients (67%) had at least one abnormal pituitary axis (hypogonadism: 62.4%; hypothyroidism: 41%, adrenal insufficiency: 30.8%, growth hormone deficiency: 29.9%; increased prolactin: 50.8%). Following surgery, the recovery rate of pituitary deficiency of one axis or more was 46% and the rate of new pituitary deficiency was 10%. Rates of LH-FSH, TSH, ACTH and GH deficiency recovery were 35.7%, 30.4%, 15.4%, and 45.5% respectively. Rates of new LH-FSH, TSH, ACTH and GH deficiencies were 8.3%, 1.6%, 9.2% and 5.1% respectively. Altogether, 24.6% of patients had a global pituitary function improvement and only 7% had pituitary function worsening after surgery. Male patients and patients with hyperprolactinemia upon diagnosis were more likely to experience pituitary function recovery. No prognostic factors for the risk of new deficiencies were identified.In a real-life cohort of patients with NFPAs, recovery of hypopituitarism after surgery is more frequent than the occurrence of new deficiencies. Hence, hypopituitarism could be considered a relative indication for surgery in patients with NFPAs." @default.
• W4377940282 created "2023-05-25" @default.
• W4377940282 creator A5001775258 @default.
• W4377940282 creator A5022557151 @default.
• W4377940282 creator A5051738297 @default.
• W4377940282 creator A5056462107 @default.
• W4377940282 creator A5056730622 @default.
• W4377940282 creator A5064891872 @default.
• W4377940282 creator A5065297105 @default.
• W4377940282 creator A5070597156 @default.
• W4377940282 creator A5074794983 @default.
• W4377940282 creator A5078902786 @default.
• W4377940282 creator A5081409867 @default.
• W4377940282 creator A5084271635 @default.
• W4377940282 date "2023-05-24" @default.
• W4377940282 modified "2023-09-26" @default.
• W4377940282 title "The impact of transsphenoidal surgery on pituitary function in patients with non-functioning macroadenomas" @default.
• W4377940282 cites W1649703361 @default.
• W4377940282 cites W1896251773 @default.
• W4377940282 cites W1912227417 @default.
• W4377940282 cites W1924769376 @default.
• W4377940282 cites W1981498768 @default.
• W4377940282 cites W2001450235 @default.
• W4377940282 cites W2020703659 @default.
• W4377940282 cites W2023143415 @default.
• W4377940282 cites W2047245583 @default.
• W4377940282 cites W2085319821 @default.
• W4377940282 cites W2092955774 @default.
• W4377940282 cites W2100396774 @default.
• W4377940282 cites W2127738340 @default.
• W4377940282 cites W2130208239 @default.
• W4377940282 cites W2132094049 @default.
• W4377940282 cites W2157870700 @default.
• W4377940282 cites W2169967426 @default.
• W4377940282 cites W2262850729 @default.
• W4377940282 cites W2265548632 @default.
• W4377940282 cites W2468793729 @default.
• W4377940282 cites W2507777550 @default.
• W4377940282 cites W2530850399 @default.
• W4377940282 cites W2769234260 @default.
• W4377940282 cites W2788126606 @default.
• W4377940282 cites W2884184874 @default.
• W4377940282 cites W3023668670 @default.
• W4377940282 cites W3152645904 @default.
• W4377940282 cites W4220675190 @default.
• W4377940282 cites W627244622 @default.
• W4377940282 cites W645253406 @default.
• W4377940282 doi "https://doi.org/10.1007/s12020-023-03400-z" @default.
• W4377940282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37222882" @default.
• W4377940282 hasPublicationYear "2023" @default.
• W4377940282 type Work @default.
• W4377940282 citedByCount "0" @default.
• W4377940282 crossrefType "journal-article" @default.
• W4377940282 hasAuthorship W4377940282A5001775258 @default.
• W4377940282 hasAuthorship W4377940282A5022557151 @default.
• W4377940282 hasAuthorship W4377940282A5051738297 @default.
• W4377940282 hasAuthorship W4377940282A5056462107 @default.
• W4377940282 hasAuthorship W4377940282A5056730622 @default.
• W4377940282 hasAuthorship W4377940282A5064891872 @default.
• W4377940282 hasAuthorship W4377940282A5065297105 @default.
• W4377940282 hasAuthorship W4377940282A5070597156 @default.
• W4377940282 hasAuthorship W4377940282A5074794983 @default.
• W4377940282 hasAuthorship W4377940282A5078902786 @default.
• W4377940282 hasAuthorship W4377940282A5081409867 @default.
• W4377940282 hasAuthorship W4377940282A5084271635 @default.
• W4377940282 hasBestOaLocation W43779402821 @default.
• W4377940282 hasConcept C126322002 @default.
• W4377940282 hasConcept C141071460 @default.
• W4377940282 hasConcept C2776958162 @default.
• W4377940282 hasConcept C2777428134 @default.
• W4377940282 hasConcept C2778491484 @default.
• W4377940282 hasConcept C2779064019 @default.
• W4377940282 hasConcept C2779318953 @default.
• W4377940282 hasConcept C2779653919 @default.
• W4377940282 hasConcept C71315377 @default.
• W4377940282 hasConcept C71924100 @default.
• W4377940282 hasConcept C72563966 @default.
• W4377940282 hasConceptScore W4377940282C126322002 @default.
• W4377940282 hasConceptScore W4377940282C141071460 @default.
• W4377940282 hasConceptScore W4377940282C2776958162 @default.
• W4377940282 hasConceptScore W4377940282C2777428134 @default.
• W4377940282 hasConceptScore W4377940282C2778491484 @default.
• W4377940282 hasConceptScore W4377940282C2779064019 @default.
• W4377940282 hasConceptScore W4377940282C2779318953 @default.
• W4377940282 hasConceptScore W4377940282C2779653919 @default.
• W4377940282 hasConceptScore W4377940282C71315377 @default.
• W4377940282 hasConceptScore W4377940282C71924100 @default.
• W4377940282 hasConceptScore W4377940282C72563966 @default.
• W4377940282 hasIssue "2" @default.
• W4377940282 hasLocation W43779402821 @default.
• W4377940282 hasLocation W43779402822 @default.
• W4377940282 hasLocation W43779402823 @default.
• W4377940282 hasOpenAccess W4377940282 @default.
• W4377940282 hasPrimaryLocation W43779402821 @default.
• W4377940282 hasRelatedWork W1581395084 @default.
• W4377940282 hasRelatedWork W1967056978 @default.
• W4377940282 hasRelatedWork W1976093913 @default.
• W4377940282 hasRelatedWork W2085319821 @default.

• next