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- W4377996970 abstract "A procedure for calculating the probability of levels of dementia is proposed using features of binocular pupil light reflex (PLR) to a chromatic light pulse on either eye. The PLR waveforms of 101 elderly participants, consisting of patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) or belonging to a normal control group (NC), were measured during four experimental conditions. Three factor scores were calculated from the PLR waveform features for each response. Responses were summarised and the differences between the two eyes were calculated in order to detect asynchronicity of PLRs in response to a light pulse on either eye. Pupillary oscillation was also measured separately without light pulses, and frequency powers were evaluated. Probabilities for the level of dementia of each participant were predicted using two types of regression functions for MCI+AD or AD patients, which were optimised using a variable selection procedure for extracted features. In the results, some variables which represent asynchronous measurement and pupillary oscillation were selected, and the requirement of binocular measurement was confirmed. A prediction procedure for levels of dementia of participants using the optimised functions was proposed, and performance was evaluated." @default.
- W4377996970 created "2023-05-25" @default.
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- W4377996970 date "2023-05-30" @default.
- W4377996970 modified "2023-10-01" @default.
- W4377996970 title "Prediction Procedure for Dementia Levels based on Waveform Features of Binocular Pupil Light Reflex" @default.
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- W4377996970 doi "https://doi.org/10.1145/3588015.3588419" @default.
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