FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378220461> ?p ?o ?g. }

• W4378220461 endingPage "724" @default.
• W4378220461 startingPage "708" @default.
• W4378220461 abstract "Patients with age-related white matter changes (ARWMC) frequently present a gait disorder, depression and cognitive impairment. Our aims are to define which alterations in the gait parameters are associated with motor or neuro-psychological impairment and to assess the role of motor, mood or cognitive dysfunction in explaining the variance of the gait parameters.Patients with gait disorders admitted to a Neuro-rehabilitation Department, affected by vascular leukoencephalopathy who had ARWMC confirmed by a brain MRI, were consecutively enrolled, classified by a neuroradiological scale (Fazekas 1987) and compared to healthy controls. We excluded subjects unable to walk independently, subjects with hydrocephalus or severe aphasia, with orthopaedic and other neurological pathologies conditioning the walking pattern. Patients and controls were assessed by clinical and functional scales (Mini Mental State Examination, Geriatric Depression Scale, Nevitt Motor Performance Scale, Berg Balance Scale, Functional Independence Measure), and computerised gait analysis was performed to assess the spatial and temporal gait parameters in a cross-sectional study.We recruited 76 patients (48 males, aged 78.3 ± 6.2 years) and 14 controls (6 males, aged 75.8 ± 5 years). In the multiple regression analysis, the gait parameter with overall best model summary values, associated with the ARWMC severity, was the stride length even after correction for age, sex, weight and height (R2 = 0.327). The motor performances justified at least in part of the gait disorder (R2 change = 0.220), but the mood state accounted independently for gait alterations (R2 change = 0.039). The increase in ARWMC severity, the reduction of motor performance and a depressed mood state were associated with a reduction of stride length (R = 0.766, R2 = 0.587), reduction of gait speed (R2 = 0.573) and an increase in double support time (R2 = 0.421).The gait disorders in patients with ARWMC are related to motor impairment, but the presence of depression is an independent factor for determining gait alterations and functional status. These data pave the way for longitudinal studies, including gait parameters, to quantitatively assess gait changes after treatment or to monitor the natural progression of the gait disorders." @default.
• W4378220461 created "2023-05-26" @default.
• W4378220461 creator A5000499726 @default.
• W4378220461 creator A5004296233 @default.
• W4378220461 creator A5009858838 @default.
• W4378220461 creator A5016573638 @default.
• W4378220461 creator A5031709566 @default.
• W4378220461 creator A5046765579 @default.
• W4378220461 creator A5073054500 @default.
• W4378220461 creator A5079780570 @default.
• W4378220461 creator A5092019155 @default.
• W4378220461 date "2023-05-25" @default.
• W4378220461 modified "2023-10-14" @default.
• W4378220461 title "Spatial and Temporal Gait Characteristics in Patients Admitted to a Neuro-Rehabilitation Department with Age-Related White Matter Changes: A Gait Analysis and Clinical Study" @default.
• W4378220461 cites W1590813564 @default.
• W4378220461 cites W1598330538 @default.
• W4378220461 cites W1646335391 @default.
• W4378220461 cites W16977820 @default.
• W4378220461 cites W1809259931 @default.
• W4378220461 cites W1839452267 @default.
• W4378220461 cites W1847168837 @default.
• W4378220461 cites W1972010401 @default.
• W4378220461 cites W1977531720 @default.
• W4378220461 cites W1978474313 @default.
• W4378220461 cites W1982967748 @default.
• W4378220461 cites W1990912178 @default.
• W4378220461 cites W2000385276 @default.
• W4378220461 cites W2000693195 @default.
• W4378220461 cites W2002667055 @default.
• W4378220461 cites W2006520062 @default.
• W4378220461 cites W2008854521 @default.
• W4378220461 cites W2009938720 @default.
• W4378220461 cites W2010776141 @default.
• W4378220461 cites W2013392796 @default.
• W4378220461 cites W2025350805 @default.
• W4378220461 cites W2044432371 @default.
• W4378220461 cites W2049023004 @default.
• W4378220461 cites W2049223406 @default.
• W4378220461 cites W2058161128 @default.
• W4378220461 cites W2065803599 @default.
• W4378220461 cites W2066329389 @default.
• W4378220461 cites W2069424609 @default.
• W4378220461 cites W2078756260 @default.
• W4378220461 cites W2078990408 @default.
• W4378220461 cites W2082027882 @default.
• W4378220461 cites W2083559033 @default.
• W4378220461 cites W2090840528 @default.
• W4378220461 cites W2091931051 @default.
• W4378220461 cites W2095287737 @default.
• W4378220461 cites W2098882356 @default.
• W4378220461 cites W2109075151 @default.
• W4378220461 cites W2115826107 @default.
• W4378220461 cites W2116569290 @default.
• W4378220461 cites W2118957880 @default.
• W4378220461 cites W2125783170 @default.
• W4378220461 cites W2125890869 @default.
• W4378220461 cites W2136451283 @default.
• W4378220461 cites W2143956929 @default.
• W4378220461 cites W2148080316 @default.
• W4378220461 cites W2157128121 @default.
• W4378220461 cites W2167311298 @default.
• W4378220461 cites W2239878504 @default.
• W4378220461 cites W2428043126 @default.
• W4378220461 cites W2482293643 @default.
• W4378220461 cites W2552939764 @default.
• W4378220461 cites W2605961743 @default.
• W4378220461 cites W2736714727 @default.
• W4378220461 cites W2774879582 @default.
• W4378220461 cites W2792461298 @default.
• W4378220461 cites W2898460024 @default.
• W4378220461 cites W2908749843 @default.
• W4378220461 cites W2910307871 @default.
• W4378220461 cites W2914251050 @default.
• W4378220461 cites W2953691333 @default.
• W4378220461 cites W2985327177 @default.
• W4378220461 cites W2996900428 @default.
• W4378220461 cites W3033918766 @default.
• W4378220461 cites W3121613769 @default.
• W4378220461 cites W3129039474 @default.
• W4378220461 cites W31641456 @default.
• W4378220461 cites W3189078083 @default.
• W4378220461 cites W4207075225 @default.
• W4378220461 cites W4229015582 @default.
• W4378220461 cites W4282925241 @default.
• W4378220461 cites W4285495163 @default.
• W4378220461 doi "https://doi.org/10.3390/neurolint15020044" @default.
• W4378220461 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37368328" @default.
• W4378220461 hasPublicationYear "2023" @default.
• W4378220461 type Work @default.
• W4378220461 citedByCount "0" @default.
• W4378220461 crossrefType "journal-article" @default.
• W4378220461 hasAuthorship W4378220461A5000499726 @default.
• W4378220461 hasAuthorship W4378220461A5004296233 @default.
• W4378220461 hasAuthorship W4378220461A5009858838 @default.
• W4378220461 hasAuthorship W4378220461A5016573638 @default.
• W4378220461 hasAuthorship W4378220461A5031709566 @default.
• W4378220461 hasAuthorship W4378220461A5046765579 @default.
• W4378220461 hasAuthorship W4378220461A5073054500 @default.

• next