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- W4378220635 abstract "Neuromyelitis optica spectrum disorder (NMOSD), a demyelinating CNS disorder in which inflammatory cells infiltrate the spinal cord and optic nerve, has been identified as an AQP4-IgG-positive disease. Some of its most common clinical characteristics are optic neuritis, acute myelitis, area postrema syndrome, and brainstem syndrome. However, the relationship between aquaporin-4 (AQP4) and NMOSD appears to be involved in pathologies outside of the CNS due to the fact that autoimmune, muscular, and paraneoplastic syndromes are more common in patients with NMOSD. This perspective presents an analysis of the current literature on neuromyelitis optica in an effort to further understand and compile pathologies that arise outside of the CNS secondary to NMOSD. Recontextualizing neuromyelitis optica as a systemic condition will facilitate greater diagnostic ability and improved treatment approaches." @default.
- W4378220635 created "2023-05-26" @default.
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- W4378220635 date "2023-05-24" @default.
- W4378220635 modified "2023-10-06" @default.
- W4378220635 title "Recontextualizing Neuromyelitis Optica as a Systemic Condition: A Perspective" @default.
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- W4378220635 doi "https://doi.org/10.3390/jcto1020008" @default.
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