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- W4378227865 abstract "Abstract A bicuspid aortic valve (BAV) is the most prevalent congenital cardiac deformity, which is associated with an increased risk to develop a thoracic aortic aneurysm and/or an aortic dissection as compared to persons with a tricuspid aortic valve. Due to the high prevalence of a BAV in the general population and the associated life-long increased risk for adverse vascular events, BAV disease places a considerable burden on the public health. The aim of the present review is to discuss the role of transforming growth factor beta (TGF-β) signaling in the development of the vascular wall and on how this complex signaling pathway may be involved in thoracic aortic aneurysm formation in tricuspid and BAV patients." @default.
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- W4378227865 date "2023-05-25" @default.
- W4378227865 modified "2023-10-14" @default.
- W4378227865 title "The role of transforming growth factor beta in bicuspid aortic valve aortopathy" @default.
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- W4378227865 doi "https://doi.org/10.1007/s12055-023-01513-8" @default.
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