Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378228670> ?p ?o ?g. }
- W4378228670 endingPage "2438" @default.
- W4378228670 startingPage "2438" @default.
- W4378228670 abstract "Solar radiation and environmental pollutants are factors that cause changes in the skin that trigger skin aging. The objective of the study is to evaluate the rejuvenating effects of a complex formed by hyaluronic acid supplemented with vitamins, amino acids and oligopeptides in explants of human skin. For this, surplus skin samples have been obtained from donors that have been resected and cultivated on slides with membrane inserts. The complex was administered to some skin explants and the percentage of cells with low, medium and high levels of melanin was evaluated as an indicator of the degree of pigmentation. Other skin segments were irradiated with UVA/UVB, then the product was administered on several slides and the levels of collagen, elastin, sulfated GAG and MMP1 were evaluated. The results show that the administration of the complex significantly reduces the percentage of skin cells with a high melanin content by 16%, and that in skin irradiated with UVA/UVB, there is a decrease in the content of collagen, elastin and sulfate GAGs, and the complex reverses this reduction without changing MMP1 levels. This suggests that the compound has anti-aging and depigmentation effects on the skin, giving a skin rejuvenation appearance." @default.
- W4378228670 created "2023-05-26" @default.
- W4378228670 creator A5028187141 @default.
- W4378228670 creator A5031373791 @default.
- W4378228670 creator A5042686889 @default.
- W4378228670 creator A5084579099 @default.
- W4378228670 date "2023-05-24" @default.
- W4378228670 modified "2023-09-30" @default.
- W4378228670 title "Anti-Aging and Depigmentation Effect of a Hyaluronic Acid Mechanically Stabilized Complex on Human Skin Explants" @default.
- W4378228670 cites W1486108320 @default.
- W4378228670 cites W1557751615 @default.
- W4378228670 cites W1769948983 @default.
- W4378228670 cites W1835696960 @default.
- W4378228670 cites W1942977330 @default.
- W4378228670 cites W1967389941 @default.
- W4378228670 cites W1967472830 @default.
- W4378228670 cites W1980379415 @default.
- W4378228670 cites W1998551889 @default.
- W4378228670 cites W2001025090 @default.
- W4378228670 cites W2017493272 @default.
- W4378228670 cites W2018020408 @default.
- W4378228670 cites W2023515195 @default.
- W4378228670 cites W2023675877 @default.
- W4378228670 cites W2028026143 @default.
- W4378228670 cites W2028942167 @default.
- W4378228670 cites W2029390954 @default.
- W4378228670 cites W2030171840 @default.
- W4378228670 cites W2033359020 @default.
- W4378228670 cites W2053728024 @default.
- W4378228670 cites W2069207562 @default.
- W4378228670 cites W2074492117 @default.
- W4378228670 cites W2075710533 @default.
- W4378228670 cites W2089378865 @default.
- W4378228670 cites W2095428878 @default.
- W4378228670 cites W2107186052 @default.
- W4378228670 cites W2132258567 @default.
- W4378228670 cites W2137541104 @default.
- W4378228670 cites W2141011422 @default.
- W4378228670 cites W2150652632 @default.
- W4378228670 cites W2158046173 @default.
- W4378228670 cites W2313226498 @default.
- W4378228670 cites W2389488453 @default.
- W4378228670 cites W2403971307 @default.
- W4378228670 cites W2409710963 @default.
- W4378228670 cites W2415627627 @default.
- W4378228670 cites W2462121468 @default.
- W4378228670 cites W2574631460 @default.
- W4378228670 cites W2609756380 @default.
- W4378228670 cites W2743764518 @default.
- W4378228670 cites W2774765706 @default.
- W4378228670 cites W2791438966 @default.
- W4378228670 cites W2797302869 @default.
- W4378228670 cites W2889931938 @default.
- W4378228670 cites W2895377446 @default.
- W4378228670 cites W2909944249 @default.
- W4378228670 cites W2926082128 @default.
- W4378228670 cites W2928450701 @default.
- W4378228670 cites W2941650397 @default.
- W4378228670 cites W2944500354 @default.
- W4378228670 cites W2968732791 @default.
- W4378228670 cites W2990368902 @default.
- W4378228670 cites W2990441106 @default.
- W4378228670 cites W3028544481 @default.
- W4378228670 cites W3047878051 @default.
- W4378228670 cites W3056820 @default.
- W4378228670 cites W3088098255 @default.
- W4378228670 cites W3094194905 @default.
- W4378228670 cites W3113481752 @default.
- W4378228670 cites W3119819287 @default.
- W4378228670 cites W3135036858 @default.
- W4378228670 cites W3153475493 @default.
- W4378228670 cites W3187068719 @default.
- W4378228670 cites W3192374766 @default.
- W4378228670 cites W3199436883 @default.
- W4378228670 cites W3202618401 @default.
- W4378228670 cites W3216501087 @default.
- W4378228670 cites W4210584951 @default.
- W4378228670 cites W4220703630 @default.
- W4378228670 cites W4226349999 @default.
- W4378228670 cites W4226434158 @default.
- W4378228670 cites W4281673628 @default.
- W4378228670 cites W4281694875 @default.
- W4378228670 cites W4282029199 @default.
- W4378228670 cites W4283456943 @default.
- W4378228670 cites W4285719527 @default.
- W4378228670 cites W4288059267 @default.
- W4378228670 cites W4302762904 @default.
- W4378228670 cites W4310829860 @default.
- W4378228670 doi "https://doi.org/10.3390/polym15112438" @default.
- W4378228670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37299236" @default.
- W4378228670 hasPublicationYear "2023" @default.
- W4378228670 type Work @default.
- W4378228670 citedByCount "0" @default.
- W4378228670 crossrefType "journal-article" @default.
- W4378228670 hasAuthorship W4378228670A5028187141 @default.
- W4378228670 hasAuthorship W4378228670A5031373791 @default.
- W4378228670 hasAuthorship W4378228670A5042686889 @default.
- W4378228670 hasAuthorship W4378228670A5084579099 @default.