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- W4378374109 abstract "In order to improve patient compliance, uniform microspheres and microcapsules have been developed for sustained release of drugs, especially of protein/peptide drugs. This chapter summarizes the research work on sustained-release microspheres and microcapsules mainly by the group in two aspects: strategies for increasing the loading efficiency and maintaining bioactivity during encapsulation, storage, and release process. Polylactic acid-based biodegradable polymers are the most common synthetic materials utilized for designing microparticles. Among them, poly(lactic acid) and poly(lactic-co-glycolic acid) are few polymers approved by Food and Drug Administration. Chitosan is a natural linear polysaccharide consisting of randomly distributed D-glucosamine and N -acetyl-D-glucosamine. It has a similar structure to mucopolysaccharide, which is extensively distributed in connective tissues and is one of the organic constituents of plasma membranes. It exhibits favorable biological characteristics such as nontoxicity, biocompatibility, biodegradability, film-forming, and antibacterial properties." @default.
- W4378374109 created "2023-05-27" @default.
- W4378374109 date "2023-05-26" @default.
- W4378374109 modified "2023-10-12" @default.
- W4378374109 title "Applications of Uniform Particles in Sustained Release of Drugs" @default.
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- W4378374109 doi "https://doi.org/10.1002/9783527830855.ch6" @default.
- W4378374109 hasPublicationYear "2023" @default.
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