FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378515211> ?p ?o ?g. }

• W4378515211 endingPage "8672" @default.
• W4378515211 startingPage "8672" @default.
• W4378515211 abstract "The current method for diagnosing methamphetamine use disorder (MUD) relies on self-reports and interviews with psychiatrists, which lack scientific rigor. This highlights the need for novel biomarkers to accurately diagnose MUD. In this study, we identified transcriptome biomarkers using hair follicles and proposed a diagnostic model for monitoring the MUD treatment process. We performed RNA sequencing analysis on hair follicle cells from healthy controls and former and current MUD patients who had been detained in the past for illegal use of methamphetamine (MA). We selected candidate genes for monitoring MUD patients by performing multivariate analysis methods, such as PCA and PLS-DA, and PPI network analysis. We developed a two-stage diagnostic model using multivariate ROC analysis based on the PLS-DA method. We constructed a two-step prediction model for MUD diagnosis using multivariate ROC analysis, including 10 biomarkers. The first step model, which distinguishes non-recovered patients from others, showed very high accuracy (prediction accuracy, 98.7%). The second step model, which distinguishes almost-recovered patients from healthy controls, showed high accuracy (prediction accuracy, 81.3%). This study is the first report to use hair follicles of MUD patients and to develop a MUD prediction model based on transcriptomic biomarkers, which offers a potential solution to improve the accuracy of MUD diagnosis and may lead to the development of better pharmacological treatments for the disorder in the future." @default.
• W4378515211 created "2023-05-28" @default.
• W4378515211 creator A5020105558 @default.
• W4378515211 creator A5033320671 @default.
• W4378515211 creator A5037963604 @default.
• W4378515211 creator A5081080530 @default.
• W4378515211 creator A5084434878 @default.
• W4378515211 creator A5088052352 @default.
• W4378515211 date "2023-05-12" @default.
• W4378515211 modified "2023-10-10" @default.
• W4378515211 title "Identification of Potential Biomarkers for Diagnosis of Patients with Methamphetamine Use Disorder" @default.
• W4378515211 cites W1238260143 @default.
• W4378515211 cites W1536164666 @default.
• W4378515211 cites W1816695864 @default.
• W4378515211 cites W1871254996 @default.
• W4378515211 cites W1926886182 @default.
• W4378515211 cites W1970357458 @default.
• W4378515211 cites W1979448745 @default.
• W4378515211 cites W1989416066 @default.
• W4378515211 cites W2008509176 @default.
• W4378515211 cites W2016731730 @default.
• W4378515211 cites W2045259007 @default.
• W4378515211 cites W2066848874 @default.
• W4378515211 cites W2079529928 @default.
• W4378515211 cites W2085669111 @default.
• W4378515211 cites W2098141312 @default.
• W4378515211 cites W2106862702 @default.
• W4378515211 cites W2109374421 @default.
• W4378515211 cites W2126104879 @default.
• W4378515211 cites W2138207763 @default.
• W4378515211 cites W2139766504 @default.
• W4378515211 cites W2145470773 @default.
• W4378515211 cites W2169456326 @default.
• W4378515211 cites W2179438025 @default.
• W4378515211 cites W2182224011 @default.
• W4378515211 cites W2238790946 @default.
• W4378515211 cites W2295124130 @default.
• W4378515211 cites W2323200483 @default.
• W4378515211 cites W2506064601 @default.
• W4378515211 cites W2547178414 @default.
• W4378515211 cites W2560639606 @default.
• W4378515211 cites W2601916337 @default.
• W4378515211 cites W2737788539 @default.
• W4378515211 cites W2784860783 @default.
• W4378515211 cites W2787687656 @default.
• W4378515211 cites W2792082233 @default.
• W4378515211 cites W2809914983 @default.
• W4378515211 cites W2883449670 @default.
• W4378515211 cites W2884244088 @default.
• W4378515211 cites W2888773346 @default.
• W4378515211 cites W2894468109 @default.
• W4378515211 cites W2974028180 @default.
• W4378515211 cites W3046725776 @default.
• W4378515211 cites W3107631561 @default.
• W4378515211 cites W3162603853 @default.
• W4378515211 cites W3163108265 @default.
• W4378515211 cites W3174601529 @default.
• W4378515211 cites W3213035715 @default.
• W4378515211 cites W4200119916 @default.
• W4378515211 cites W4221053919 @default.
• W4378515211 cites W4297227091 @default.
• W4378515211 doi "https://doi.org/10.3390/ijms24108672" @default.
• W4378515211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37240016" @default.
• W4378515211 hasPublicationYear "2023" @default.
• W4378515211 type Work @default.
• W4378515211 citedByCount "0" @default.
• W4378515211 crossrefType "journal-article" @default.
• W4378515211 hasAuthorship W4378515211A5020105558 @default.
• W4378515211 hasAuthorship W4378515211A5033320671 @default.
• W4378515211 hasAuthorship W4378515211A5037963604 @default.
• W4378515211 hasAuthorship W4378515211A5081080530 @default.
• W4378515211 hasAuthorship W4378515211A5084434878 @default.
• W4378515211 hasAuthorship W4378515211A5088052352 @default.
• W4378515211 hasBestOaLocation W43785152111 @default.
• W4378515211 hasConcept C116834253 @default.
• W4378515211 hasConcept C119857082 @default.
• W4378515211 hasConcept C126322002 @default.
• W4378515211 hasConcept C161584116 @default.
• W4378515211 hasConcept C18903297 @default.
• W4378515211 hasConcept C2781197716 @default.
• W4378515211 hasConcept C3020132585 @default.
• W4378515211 hasConcept C38180746 @default.
• W4378515211 hasConcept C41008148 @default.
• W4378515211 hasConcept C54355233 @default.
• W4378515211 hasConcept C58471807 @default.
• W4378515211 hasConcept C70721500 @default.
• W4378515211 hasConcept C71924100 @default.
• W4378515211 hasConcept C86803240 @default.
• W4378515211 hasConceptScore W4378515211C116834253 @default.
• W4378515211 hasConceptScore W4378515211C119857082 @default.
• W4378515211 hasConceptScore W4378515211C126322002 @default.
• W4378515211 hasConceptScore W4378515211C161584116 @default.
• W4378515211 hasConceptScore W4378515211C18903297 @default.
• W4378515211 hasConceptScore W4378515211C2781197716 @default.
• W4378515211 hasConceptScore W4378515211C3020132585 @default.
• W4378515211 hasConceptScore W4378515211C38180746 @default.
• W4378515211 hasConceptScore W4378515211C41008148 @default.
• W4378515211 hasConceptScore W4378515211C54355233 @default.

• next