Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378575934> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4378575934 endingPage "1857" @default.
- W4378575934 startingPage "1857" @default.
- W4378575934 abstract "(1) Background: Human SERPINB5, commonly known as maspin, has diverse functions as a tumor suppressor. Maspin has a novel role in cell cycle control, and common variants were discovered to be associated with gastric cancer (GC). Maspin was proven to also affect the EMT and angiogenesis of gastric cancer cells via the ITGB1/FAK pathway. Information about the maspin concentrations correlated with different pathological features of the patients may facilitate the fast diagnosis and personalized treatment of patients. The novelty of this study is given by the correlations established for the maspin levels in different biological features and clinicopathological features. These correlations can be extremely useful for surgeons and oncologists. (2) Patients and methods: Patients with clinical and pathological features, given the small number of samples available for this study, were selected from the database of the project GRAPHSENSGASTROINTES, and used in accordance with the Ethics Committee approval nr. 32,647/2018 awarded by the County Emergency Hospital from Targu-Mures. Stochastic microsensors were used as new screening tools for the determination of the concentration of maspin in four types of samples: tumoral tissues, blood, saliva and urine. (3) Results: The results obtained using the stochastic sensors were correlated with those tabulated in the clinical and pathological database. A series of assumptions regarding the values and practice important features for surgeons and pathologists were made. (4) Conclusions: This study provided a few assumptions regarding the correlations between the values of maspin levels in the analyzed samples and the clinical and pathological features. These results may be useful as preoperative investigations in order to help surgeons localize, approximate and choose the best treatment. These correlations may facilitate minim invasive and fast diagnosis of gastric cancer based on reliable detection of maspin concentration in biological samples (tumoral tissues, blood, saliva and urine)." @default.
- W4378575934 created "2023-05-28" @default.
- W4378575934 creator A5005724703 @default.
- W4378575934 creator A5056980183 @default.
- W4378575934 date "2023-05-26" @default.
- W4378575934 modified "2023-10-14" @default.
- W4378575934 title "Minimally Invasive and Fast Diagnosis of Gastric Cancer Based on Maspin Levels in Different Biological Samples" @default.
- W4378575934 cites W188161392 @default.
- W4378575934 cites W1966698554 @default.
- W4378575934 cites W1982417023 @default.
- W4378575934 cites W1992579947 @default.
- W4378575934 cites W2045271204 @default.
- W4378575934 cites W2085831757 @default.
- W4378575934 cites W2091657079 @default.
- W4378575934 cites W2131449144 @default.
- W4378575934 cites W2148744610 @default.
- W4378575934 cites W2943627017 @default.
- W4378575934 cites W3024941666 @default.
- W4378575934 cites W4211125414 @default.
- W4378575934 cites W4220782044 @default.
- W4378575934 cites W4295974684 @default.
- W4378575934 cites W4296103988 @default.
- W4378575934 cites W4301367231 @default.
- W4378575934 cites W4307551447 @default.
- W4378575934 cites W4309212006 @default.
- W4378575934 cites W4310989655 @default.
- W4378575934 doi "https://doi.org/10.3390/diagnostics13111857" @default.
- W4378575934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37296710" @default.
- W4378575934 hasPublicationYear "2023" @default.
- W4378575934 type Work @default.
- W4378575934 citedByCount "0" @default.
- W4378575934 crossrefType "journal-article" @default.
- W4378575934 hasAuthorship W4378575934A5005724703 @default.
- W4378575934 hasAuthorship W4378575934A5056980183 @default.
- W4378575934 hasBestOaLocation W43785759341 @default.
- W4378575934 hasConcept C121608353 @default.
- W4378575934 hasConcept C126322002 @default.
- W4378575934 hasConcept C142724271 @default.
- W4378575934 hasConcept C143998085 @default.
- W4378575934 hasConcept C207886595 @default.
- W4378575934 hasConcept C2778900538 @default.
- W4378575934 hasConcept C2779013556 @default.
- W4378575934 hasConcept C2780394083 @default.
- W4378575934 hasConcept C71924100 @default.
- W4378575934 hasConceptScore W4378575934C121608353 @default.
- W4378575934 hasConceptScore W4378575934C126322002 @default.
- W4378575934 hasConceptScore W4378575934C142724271 @default.
- W4378575934 hasConceptScore W4378575934C143998085 @default.
- W4378575934 hasConceptScore W4378575934C207886595 @default.
- W4378575934 hasConceptScore W4378575934C2778900538 @default.
- W4378575934 hasConceptScore W4378575934C2779013556 @default.
- W4378575934 hasConceptScore W4378575934C2780394083 @default.
- W4378575934 hasConceptScore W4378575934C71924100 @default.
- W4378575934 hasFunder F4320323983 @default.
- W4378575934 hasIssue "11" @default.
- W4378575934 hasLocation W43785759341 @default.
- W4378575934 hasLocation W43785759342 @default.
- W4378575934 hasOpenAccess W4378575934 @default.
- W4378575934 hasPrimaryLocation W43785759341 @default.
- W4378575934 hasRelatedWork W1502713173 @default.
- W4378575934 hasRelatedWork W1982742522 @default.
- W4378575934 hasRelatedWork W2058948935 @default.
- W4378575934 hasRelatedWork W2065743508 @default.
- W4378575934 hasRelatedWork W2107641286 @default.
- W4378575934 hasRelatedWork W2443517485 @default.
- W4378575934 hasRelatedWork W2808509624 @default.
- W4378575934 hasRelatedWork W3001477125 @default.
- W4378575934 hasRelatedWork W4236189662 @default.
- W4378575934 hasRelatedWork W50871686 @default.
- W4378575934 hasVolume "13" @default.
- W4378575934 isParatext "false" @default.
- W4378575934 isRetracted "false" @default.
- W4378575934 workType "article" @default.