FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378620152> ?p ?o ?g. }

• W4378620152 abstract "Compelling evidence has mounted surrounding the relationship between the gut microbiome and many intestinal and extraintestinal cancers. Few studies exist investigating the relationship between the gut microbiome and sarcoma. We hypothesize that the presence of distant osteosarcoma induces change to the profile of flora within the mouse. Twelve mice were used for this experiment: six were sedated and received an injection of human osteosarcoma cells into the flank, while six served as controls. Baseline stool and weight were collected. Tumor size and mouse weight were recorded weekly, and stool samples were collected and stored. Fecal microbiomes of the mice were profiled by 16S rRNA gene sequencing and analyzed for alpha diversity, relative abundances of microbial taxa, and abundance of specific bacteria at different time points. Alpha diversity was increased in the osteosarcoma group compared with the control group. The family Lachnospiraceae had the second strongest negative net average change in relative abundance over time in the osteosarcoma group whereas it had a positive net average change in the control group. An increased Firmicutes/Bacteroidota (F/B) ratio was observed in the osteosarcoma group relative to the control mice. These differences suggest that there may be an interplay between the gut microbiome and osteosarcoma. Clinical significance: Due to the paucity of literature available, our work can support novel research on this relationship and the development of new, personalized treatments for osteosarcoma." @default.
• W4378620152 created "2023-05-29" @default.
• W4378620152 creator A5005496569 @default.
• W4378620152 creator A5011221675 @default.
• W4378620152 creator A5037139192 @default.
• W4378620152 creator A5040884561 @default.
• W4378620152 date "2023-06-08" @default.
• W4378620152 modified "2023-10-14" @default.
• W4378620152 title "Characterization of the gut microbiome in an osteosarcoma mouse model" @default.
• W4378620152 cites W2015567271 @default.
• W4378620152 cites W2073238763 @default.
• W4378620152 cites W211380578 @default.
• W4378620152 cites W2113882071 @default.
• W4378620152 cites W2142136189 @default.
• W4378620152 cites W2166171121 @default.
• W4378620152 cites W2201127965 @default.
• W4378620152 cites W2254642444 @default.
• W4378620152 cites W2310707027 @default.
• W4378620152 cites W2324431491 @default.
• W4378620152 cites W2401404581 @default.
• W4378620152 cites W2469986620 @default.
• W4378620152 cites W2584763199 @default.
• W4378620152 cites W2589489476 @default.
• W4378620152 cites W2742147437 @default.
• W4378620152 cites W2766903152 @default.
• W4378620152 cites W2796231261 @default.
• W4378620152 cites W2800461749 @default.
• W4378620152 cites W2811099396 @default.
• W4378620152 cites W2902029737 @default.
• W4378620152 cites W2963276645 @default.
• W4378620152 cites W2972964609 @default.
• W4378620152 cites W2979882441 @default.
• W4378620152 cites W3009468907 @default.
• W4378620152 cites W3027118763 @default.
• W4378620152 cites W3039328198 @default.
• W4378620152 cites W3117864613 @default.
• W4378620152 cites W3125898497 @default.
• W4378620152 cites W3161627884 @default.
• W4378620152 cites W3184846858 @default.
• W4378620152 cites W3191998012 @default.
• W4378620152 cites W3194124095 @default.
• W4378620152 cites W3199242823 @default.
• W4378620152 cites W3215539928 @default.
• W4378620152 cites W4280576091 @default.
• W4378620152 cites W4281797937 @default.
• W4378620152 cites W4313545226 @default.
• W4378620152 doi "https://doi.org/10.1002/jor.25635" @default.
• W4378620152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37246455" @default.
• W4378620152 hasPublicationYear "2023" @default.
• W4378620152 type Work @default.
• W4378620152 citedByCount "0" @default.
• W4378620152 crossrefType "journal-article" @default.
• W4378620152 hasAuthorship W4378620152A5005496569 @default.
• W4378620152 hasAuthorship W4378620152A5011221675 @default.
• W4378620152 hasAuthorship W4378620152A5037139192 @default.
• W4378620152 hasAuthorship W4378620152A5040884561 @default.
• W4378620152 hasConcept C122325731 @default.
• W4378620152 hasConcept C126322002 @default.
• W4378620152 hasConcept C142724271 @default.
• W4378620152 hasConcept C143121216 @default.
• W4378620152 hasConcept C18903297 @default.
• W4378620152 hasConcept C203014093 @default.
• W4378620152 hasConcept C2777695942 @default.
• W4378620152 hasConcept C2777760704 @default.
• W4378620152 hasConcept C2778256501 @default.
• W4378620152 hasConcept C2779704485 @default.
• W4378620152 hasConcept C42062724 @default.
• W4378620152 hasConcept C502942594 @default.
• W4378620152 hasConcept C523546767 @default.
• W4378620152 hasConcept C539455810 @default.
• W4378620152 hasConcept C54355233 @default.
• W4378620152 hasConcept C61716771 @default.
• W4378620152 hasConcept C71924100 @default.
• W4378620152 hasConcept C77077793 @default.
• W4378620152 hasConcept C86803240 @default.
• W4378620152 hasConcept C89423630 @default.
• W4378620152 hasConceptScore W4378620152C122325731 @default.
• W4378620152 hasConceptScore W4378620152C126322002 @default.
• W4378620152 hasConceptScore W4378620152C142724271 @default.
• W4378620152 hasConceptScore W4378620152C143121216 @default.
• W4378620152 hasConceptScore W4378620152C18903297 @default.
• W4378620152 hasConceptScore W4378620152C203014093 @default.
• W4378620152 hasConceptScore W4378620152C2777695942 @default.
• W4378620152 hasConceptScore W4378620152C2777760704 @default.
• W4378620152 hasConceptScore W4378620152C2778256501 @default.
• W4378620152 hasConceptScore W4378620152C2779704485 @default.
• W4378620152 hasConceptScore W4378620152C42062724 @default.
• W4378620152 hasConceptScore W4378620152C502942594 @default.
• W4378620152 hasConceptScore W4378620152C523546767 @default.
• W4378620152 hasConceptScore W4378620152C539455810 @default.
• W4378620152 hasConceptScore W4378620152C54355233 @default.
• W4378620152 hasConceptScore W4378620152C61716771 @default.
• W4378620152 hasConceptScore W4378620152C71924100 @default.
• W4378620152 hasConceptScore W4378620152C77077793 @default.
• W4378620152 hasConceptScore W4378620152C86803240 @default.
• W4378620152 hasConceptScore W4378620152C89423630 @default.
• W4378620152 hasLocation W43786201521 @default.
• W4378620152 hasLocation W43786201522 @default.
• W4378620152 hasOpenAccess W4378620152 @default.
• W4378620152 hasPrimaryLocation W43786201521 @default.

• next