Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378697817> ?p ?o ?g. }
- W4378697817 abstract "Local overexposure to ionizing radiation leads to chronic inflammation, vascular damage and cachexia. Here we investigate the kinetics of inflammatory cells from day (D)1 to D180 after mouse hindlimb irradiation and analyze the role of monocyte (Mo) subsets in tissue revascularization. At D1, we find that Mo and T cells are mobilized from spleen and bone marrow to the blood. New vessel formation during early phase, as demonstrated by ~1.4- and 2-fold increased angiographic score and capillary density, respectively, correlates with an increase of circulating T cells, and Mohi and type 1-like macrophages in irradiated muscle. At D90 vascular rarefaction and cachexia are observed, associated with decreased numbers of circulating Molo and Type 2-like macrophages in irradiated tissue. Moreover, CCR2- and CX3CR1-deficency negatively influences neovascularization. However adoptive transfer of Mohi enhances vessel growth. Our data demonstrate the radiation-induced dynamic inflammatory waves and the major role of inflammatory cells in neovascularization." @default.
- W4378697817 created "2023-05-30" @default.
- W4378697817 creator A5008214462 @default.
- W4378697817 creator A5017658037 @default.
- W4378697817 creator A5041762737 @default.
- W4378697817 creator A5064769912 @default.
- W4378697817 creator A5074641512 @default.
- W4378697817 creator A5089356253 @default.
- W4378697817 date "2023-05-29" @default.
- W4378697817 modified "2023-09-30" @default.
- W4378697817 title "Inflammatory cells dynamics control neovascularization and tissue healing after localized radiation induced injury in mice" @default.
- W4378697817 cites W1487555374 @default.
- W4378697817 cites W1574172480 @default.
- W4378697817 cites W1970017835 @default.
- W4378697817 cites W1978859651 @default.
- W4378697817 cites W1981603155 @default.
- W4378697817 cites W1985502949 @default.
- W4378697817 cites W1987936572 @default.
- W4378697817 cites W1994682147 @default.
- W4378697817 cites W1995827857 @default.
- W4378697817 cites W2003571290 @default.
- W4378697817 cites W2003870922 @default.
- W4378697817 cites W2005961677 @default.
- W4378697817 cites W2008669330 @default.
- W4378697817 cites W2010914305 @default.
- W4378697817 cites W2018448066 @default.
- W4378697817 cites W2019349022 @default.
- W4378697817 cites W2020546717 @default.
- W4378697817 cites W2022585532 @default.
- W4378697817 cites W2023839748 @default.
- W4378697817 cites W2024740314 @default.
- W4378697817 cites W2029412466 @default.
- W4378697817 cites W2043436213 @default.
- W4378697817 cites W2044286483 @default.
- W4378697817 cites W2051870680 @default.
- W4378697817 cites W2054095354 @default.
- W4378697817 cites W2059680693 @default.
- W4378697817 cites W2062410438 @default.
- W4378697817 cites W2064752763 @default.
- W4378697817 cites W2065145765 @default.
- W4378697817 cites W2065456584 @default.
- W4378697817 cites W2077217313 @default.
- W4378697817 cites W2085701716 @default.
- W4378697817 cites W2095670074 @default.
- W4378697817 cites W2100190333 @default.
- W4378697817 cites W2108723188 @default.
- W4378697817 cites W2117971367 @default.
- W4378697817 cites W2119679153 @default.
- W4378697817 cites W2122311980 @default.
- W4378697817 cites W2123245071 @default.
- W4378697817 cites W2123968945 @default.
- W4378697817 cites W2135119053 @default.
- W4378697817 cites W2135647797 @default.
- W4378697817 cites W2136325680 @default.
- W4378697817 cites W2142750845 @default.
- W4378697817 cites W2151422561 @default.
- W4378697817 cites W2152063570 @default.
- W4378697817 cites W2154676325 @default.
- W4378697817 cites W2156013098 @default.
- W4378697817 cites W2158380859 @default.
- W4378697817 cites W2161933793 @default.
- W4378697817 cites W2163993647 @default.
- W4378697817 cites W2170313716 @default.
- W4378697817 cites W2267585616 @default.
- W4378697817 cites W2317138533 @default.
- W4378697817 cites W2345479752 @default.
- W4378697817 cites W2601578122 @default.
- W4378697817 cites W3015811931 @default.
- W4378697817 cites W4214505185 @default.
- W4378697817 cites W4318816941 @default.
- W4378697817 cites W2416567560 @default.
- W4378697817 doi "https://doi.org/10.1038/s42003-023-04939-3" @default.
- W4378697817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37248293" @default.
- W4378697817 hasPublicationYear "2023" @default.
- W4378697817 type Work @default.
- W4378697817 citedByCount "0" @default.
- W4378697817 crossrefType "journal-article" @default.
- W4378697817 hasAuthorship W4378697817A5008214462 @default.
- W4378697817 hasAuthorship W4378697817A5017658037 @default.
- W4378697817 hasAuthorship W4378697817A5041762737 @default.
- W4378697817 hasAuthorship W4378697817A5064769912 @default.
- W4378697817 hasAuthorship W4378697817A5074641512 @default.
- W4378697817 hasAuthorship W4378697817A5089356253 @default.
- W4378697817 hasBestOaLocation W43786978171 @default.
- W4378697817 hasConcept C111337013 @default.
- W4378697817 hasConcept C121332964 @default.
- W4378697817 hasConcept C12823836 @default.
- W4378697817 hasConcept C13373296 @default.
- W4378697817 hasConcept C142724271 @default.
- W4378697817 hasConcept C18231593 @default.
- W4378697817 hasConcept C185544564 @default.
- W4378697817 hasConcept C185592680 @default.
- W4378697817 hasConcept C203014093 @default.
- W4378697817 hasConcept C2776914184 @default.
- W4378697817 hasConcept C2778271429 @default.
- W4378697817 hasConcept C2780007613 @default.
- W4378697817 hasConcept C2780394083 @default.
- W4378697817 hasConcept C2780931953 @default.
- W4378697817 hasConcept C2781184567 @default.
- W4378697817 hasConcept C31179232 @default.