FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378715548> ?p ?o ?g. }

• W4378715548 endingPage "105" @default.
• W4378715548 startingPage "105" @default.
• W4378715548 abstract "BACKGROUND: Trace elements normally appear in low concentrations in the human body and play an important role in the enzyme systems in many metabolic processes. Trace elements, mostly selenium (Se) and zinc (Zn), were involved in the defense against oxidative stress in cells. Oxidation could lead to the generation of free radicals that have been involved in the pathogenesis of many diseases, including leukemia. While Cu at the physiological level provides cellular health and at higher than the physiological level causes angiogenesis and a higher incidence of cancers.Objectives: The aim of this study was to measure the essential trace elements (selenium, zinc, and copper) in the serum of adult patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) and their relation to some clinical and laboratory parameters.Materials and Methods: This case–control study comprised 39 adult patients with de novo acute leukemia (AL) (28 patients with AML and 11 patients with ALL) conducted from January to June 2022. The patients were collected from Iraqi Center for Hematology in Baghdad Teaching Hospital in Medical City. A total of 40 apparently healthy adults were included in this study as a control group. Peripheral blood and bone marrow smears were examined at the presentation for establishing the diagnosis. The serum level of selenium, zinc, and copper was measured by a microplate reader for both patients and the control group, before starting chemotherapy. Immunophenotyping and renal function tests (RFTs) were taken from the patient's files.RESULTS: There was a statistically lower median level of selenium among the patients group in comparison to the control group (P < 0.001), while both zinc and copper did not show statistical difference between both groups (P > 0.05). Only hemoglobin (Hb) showed a significant negative correlation between patients with AL and the level of selenium. There was a significantly lower zinc level among the abnormal RFT group in comparison to the normal group.CONCLUSIONS: There was a significantly lower serum selenium level in AL patients than in the control group. Selenium level showed a negative correlation with Hb among AL patients only, in which an increase in selenium level was associated with a decrease in Hb level among AL patients. There was no significant difference in the serum level of zinc and copper between AL patients and the control group. There was a significantly lower zinc level among the abnormal RFT group in comparison to the normal group." @default.
• W4378715548 created "2023-05-30" @default.
• W4378715548 creator A5018044807 @default.
• W4378715548 creator A5072555090 @default.
• W4378715548 date "2023-01-01" @default.
• W4378715548 modified "2023-10-16" @default.
• W4378715548 title "Trace elements (selenium, copper and zinc) in de novo acute leukemia: serum levels and their relation with some clinical and laboratory parameters" @default.
• W4378715548 cites W1792088298 @default.
• W4378715548 cites W2057584257 @default.
• W4378715548 cites W2066349968 @default.
• W4378715548 cites W2129489356 @default.
• W4378715548 cites W2130318636 @default.
• W4378715548 cites W2161688851 @default.
• W4378715548 cites W2902763835 @default.
• W4378715548 cites W2936414910 @default.
• W4378715548 cites W2971049095 @default.
• W4378715548 cites W2972110098 @default.
• W4378715548 cites W2980761235 @default.
• W4378715548 cites W3012767391 @default.
• W4378715548 cites W3092590621 @default.
• W4378715548 cites W3142115670 @default.
• W4378715548 cites W3148789905 @default.
• W4378715548 doi "https://doi.org/10.4103/ijh.ijh_33_23" @default.
• W4378715548 hasPublicationYear "2023" @default.
• W4378715548 type Work @default.
• W4378715548 citedByCount "0" @default.
• W4378715548 crossrefType "journal-article" @default.
• W4378715548 hasAuthorship W4378715548A5018044807 @default.
• W4378715548 hasAuthorship W4378715548A5072555090 @default.
• W4378715548 hasBestOaLocation W43787155481 @default.
• W4378715548 hasConcept C120665830 @default.
• W4378715548 hasConcept C121332964 @default.
• W4378715548 hasConcept C126322002 @default.
• W4378715548 hasConcept C178790620 @default.
• W4378715548 hasConcept C185592680 @default.
• W4378715548 hasConcept C194409129 @default.
• W4378715548 hasConcept C203014093 @default.
• W4378715548 hasConcept C2776863199 @default.
• W4378715548 hasConcept C2778461978 @default.
• W4378715548 hasConcept C2778729363 @default.
• W4378715548 hasConcept C42407357 @default.
• W4378715548 hasConcept C535196362 @default.
• W4378715548 hasConcept C553756173 @default.
• W4378715548 hasConcept C61511704 @default.
• W4378715548 hasConcept C71924100 @default.
• W4378715548 hasConcept C90924648 @default.
• W4378715548 hasConceptScore W4378715548C120665830 @default.
• W4378715548 hasConceptScore W4378715548C121332964 @default.
• W4378715548 hasConceptScore W4378715548C126322002 @default.
• W4378715548 hasConceptScore W4378715548C178790620 @default.
• W4378715548 hasConceptScore W4378715548C185592680 @default.
• W4378715548 hasConceptScore W4378715548C194409129 @default.
• W4378715548 hasConceptScore W4378715548C203014093 @default.
• W4378715548 hasConceptScore W4378715548C2776863199 @default.
• W4378715548 hasConceptScore W4378715548C2778461978 @default.
• W4378715548 hasConceptScore W4378715548C2778729363 @default.
• W4378715548 hasConceptScore W4378715548C42407357 @default.
• W4378715548 hasConceptScore W4378715548C535196362 @default.
• W4378715548 hasConceptScore W4378715548C553756173 @default.
• W4378715548 hasConceptScore W4378715548C61511704 @default.
• W4378715548 hasConceptScore W4378715548C71924100 @default.
• W4378715548 hasConceptScore W4378715548C90924648 @default.
• W4378715548 hasIssue "1" @default.
• W4378715548 hasLocation W43787155481 @default.
• W4378715548 hasOpenAccess W4378715548 @default.
• W4378715548 hasPrimaryLocation W43787155481 @default.
• W4378715548 hasRelatedWork W2030349286 @default.
• W4378715548 hasRelatedWork W2053377136 @default.
• W4378715548 hasRelatedWork W2068835074 @default.
• W4378715548 hasRelatedWork W2161603182 @default.
• W4378715548 hasRelatedWork W2350274480 @default.
• W4378715548 hasRelatedWork W2393383561 @default.
• W4378715548 hasRelatedWork W2394313917 @default.
• W4378715548 hasRelatedWork W2616246374 @default.
• W4378715548 hasRelatedWork W3160786202 @default.
• W4378715548 hasRelatedWork W3181573727 @default.
• W4378715548 hasVolume "12" @default.
• W4378715548 isParatext "false" @default.
• W4378715548 isRetracted "false" @default.
• W4378715548 workType "article" @default.