Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378779738> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4378779738 endingPage "296" @default.
- W4378779738 startingPage "287" @default.
- W4378779738 abstract "The increasing incidence of mortality due to benign prostatic hyperplasia (BPH) in ageing men globally is of serious concern and needed collective efforts to arrest it. The benign prostatic hyperplasia result from excessive growth of the prostate gland due to proliferating cells which impairs urethral functions by compressing it. This present study evaluated the effect of methanol extract of Allium sativa (MEAS) on lipid profile, renal and hepatic function biomarkers of testosterone induced benign prostate hyperplasia in male rats. The study was done using 25 adult male albino rats, divided into 5 groups, which comprises of normal control, negative control, positive control, and BPH induced rats treated with 200 and 400 mg/kg /day of MEAS respectively. Hepatic and renal biomarkers (ALT, AST, ALP, Urea, Creatinine) and lipid profile (HDL, LDL, TAG, CHOL were evaluated. The BPH induction caused significant (p<0.05) increases in lipid profile with exception HDL; hepatic and renal biomarkers of the negative control when compared with the normal control. The MEAS treated BPH-induced rats had significant (p>0.05) reduction in the biochemical biomarkers with significant (p<0.05) increase HDL. The findings of this study indicated that BPH impairs cellular functionality and treatment of BPH with methanol extract of Allium sativa showed to be effective. Therefore, extract of Allium sativa is a potential agent for the treatment of benign prostatic hyperplasia." @default.
- W4378779738 created "2023-05-31" @default.
- W4378779738 creator A5022903122 @default.
- W4378779738 creator A5042139748 @default.
- W4378779738 creator A5086542815 @default.
- W4378779738 date "2023-05-13" @default.
- W4378779738 modified "2023-09-28" @default.
- W4378779738 title "Effects of methanol extract of Allium sativa (MEAS) on hepatic and renal function biomarkers and Lipid profile of Testosterone propionate induced Benign Prostatic Hyperplasia male Rats" @default.
- W4378779738 doi "https://doi.org/10.36348/sjmps.2023.v09i05.003" @default.
- W4378779738 hasPublicationYear "2023" @default.
- W4378779738 type Work @default.
- W4378779738 citedByCount "0" @default.
- W4378779738 crossrefType "journal-article" @default.
- W4378779738 hasAuthorship W4378779738A5022903122 @default.
- W4378779738 hasAuthorship W4378779738A5042139748 @default.
- W4378779738 hasAuthorship W4378779738A5086542815 @default.
- W4378779738 hasBestOaLocation W43787797381 @default.
- W4378779738 hasConcept C121608353 @default.
- W4378779738 hasConcept C126322002 @default.
- W4378779738 hasConcept C126894567 @default.
- W4378779738 hasConcept C134018914 @default.
- W4378779738 hasConcept C159641895 @default.
- W4378779738 hasConcept C2776235491 @default.
- W4378779738 hasConcept C2777562237 @default.
- W4378779738 hasConcept C2777911890 @default.
- W4378779738 hasConcept C2778163477 @default.
- W4378779738 hasConcept C2778270857 @default.
- W4378779738 hasConcept C2779279991 @default.
- W4378779738 hasConcept C2780306776 @default.
- W4378779738 hasConcept C2781115071 @default.
- W4378779738 hasConcept C71315377 @default.
- W4378779738 hasConcept C71924100 @default.
- W4378779738 hasConceptScore W4378779738C121608353 @default.
- W4378779738 hasConceptScore W4378779738C126322002 @default.
- W4378779738 hasConceptScore W4378779738C126894567 @default.
- W4378779738 hasConceptScore W4378779738C134018914 @default.
- W4378779738 hasConceptScore W4378779738C159641895 @default.
- W4378779738 hasConceptScore W4378779738C2776235491 @default.
- W4378779738 hasConceptScore W4378779738C2777562237 @default.
- W4378779738 hasConceptScore W4378779738C2777911890 @default.
- W4378779738 hasConceptScore W4378779738C2778163477 @default.
- W4378779738 hasConceptScore W4378779738C2778270857 @default.
- W4378779738 hasConceptScore W4378779738C2779279991 @default.
- W4378779738 hasConceptScore W4378779738C2780306776 @default.
- W4378779738 hasConceptScore W4378779738C2781115071 @default.
- W4378779738 hasConceptScore W4378779738C71315377 @default.
- W4378779738 hasConceptScore W4378779738C71924100 @default.
- W4378779738 hasIssue "05" @default.
- W4378779738 hasLocation W43787797381 @default.
- W4378779738 hasOpenAccess W4378779738 @default.
- W4378779738 hasPrimaryLocation W43787797381 @default.
- W4378779738 hasRelatedWork W1977970588 @default.
- W4378779738 hasRelatedWork W1992438146 @default.
- W4378779738 hasRelatedWork W2001381637 @default.
- W4378779738 hasRelatedWork W2014764273 @default.
- W4378779738 hasRelatedWork W2022659954 @default.
- W4378779738 hasRelatedWork W2101146068 @default.
- W4378779738 hasRelatedWork W2142667461 @default.
- W4378779738 hasRelatedWork W2146554192 @default.
- W4378779738 hasRelatedWork W2611776224 @default.
- W4378779738 hasRelatedWork W3104376036 @default.
- W4378779738 hasVolume "9" @default.
- W4378779738 isParatext "false" @default.
- W4378779738 isRetracted "false" @default.
- W4378779738 workType "article" @default.