Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378834372> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4378834372 abstract "To increase the prediction accuracy of positive oral food challenge (OFC) outcome during stepwise slow oral immunotherapy (SS-OIT) in children with hen’s egg (HE) allergy, we evaluated the predictive value of the combination of antigen-specific IgE (sIgE) with antigen binding-avidity and sIgG4 values. Sixty-three children with HE allergy undergoing SS-OIT were subjected to repeated OFC with HE. We measured the ovomucoid (OVM)-sIgE by ImmunoCAP or densely carboxylated protein (DCP) microarray, sIgG4 by DCP microarray, and the binding-avidity of OVM-sIgE defined as the level of 1/ IC50 (nM) measured by competitive binding inhibition assays. The OFC was positive in 37 (59%) patients undergoing SS-OIT. Significant differences in DCP-OVM-sIgE, CAP-OVM-sIgE, I/ IC50, DCP-OVM-sIgG4, the multiplication products of DCP-OVM-sIgE and binding-avidity of DCP-OVM-sIgE (DCP-OVM-sIgE/IC50) and DCP-OVM-sIgE/sIgG4 were compared between the negative and positive groups (p<0.01). Among them, the variable with greatest area under the receiver operating characteristic curve was DCP-OVM-sIgE/IC50 (0.84), followed by DCP-OVM-sIgE/sIgG4 (0.81). DCP-OVM-sIgE/IC50 and DCP-OVM-sIgE/sIgG4 are potentially useful markers for the prediction of positive OFC during HE-SS-OIT and may allow proper evaluation of the current allergic status in the healing process during HE-SS-OIT" @default.
- W4378834372 created "2023-06-01" @default.
- W4378834372 creator A5008972022 @default.
- W4378834372 creator A5011374919 @default.
- W4378834372 creator A5013695615 @default.
- W4378834372 creator A5030402215 @default.
- W4378834372 creator A5051933265 @default.
- W4378834372 creator A5059247664 @default.
- W4378834372 creator A5069973766 @default.
- W4378834372 creator A5071360328 @default.
- W4378834372 creator A5077482664 @default.
- W4378834372 creator A5087962680 @default.
- W4378834372 date "2023-05-31" @default.
- W4378834372 modified "2023-10-01" @default.
- W4378834372 title "The Combination of Binding-Avidity of Ovomucoid-Specific IgE Antibody and Specific IgG4 Antibody Can Predict Positive Outcome of Oral Food Challenge during Stepwise Slow Oral Immunotherapy in Children with Hen’s Egg Allergy" @default.
- W4378834372 doi "https://doi.org/10.20944/preprints202305.1836.v3" @default.
- W4378834372 hasPublicationYear "2023" @default.
- W4378834372 type Work @default.
- W4378834372 citedByCount "0" @default.
- W4378834372 crossrefType "posted-content" @default.
- W4378834372 hasAuthorship W4378834372A5008972022 @default.
- W4378834372 hasAuthorship W4378834372A5011374919 @default.
- W4378834372 hasAuthorship W4378834372A5013695615 @default.
- W4378834372 hasAuthorship W4378834372A5030402215 @default.
- W4378834372 hasAuthorship W4378834372A5051933265 @default.
- W4378834372 hasAuthorship W4378834372A5059247664 @default.
- W4378834372 hasAuthorship W4378834372A5069973766 @default.
- W4378834372 hasAuthorship W4378834372A5071360328 @default.
- W4378834372 hasAuthorship W4378834372A5077482664 @default.
- W4378834372 hasAuthorship W4378834372A5087962680 @default.
- W4378834372 hasBestOaLocation W43788343721 @default.
- W4378834372 hasConcept C141105273 @default.
- W4378834372 hasConcept C147483822 @default.
- W4378834372 hasConcept C159654299 @default.
- W4378834372 hasConcept C179223381 @default.
- W4378834372 hasConcept C185592680 @default.
- W4378834372 hasConcept C202751555 @default.
- W4378834372 hasConcept C203014093 @default.
- W4378834372 hasConcept C207480886 @default.
- W4378834372 hasConcept C2776027960 @default.
- W4378834372 hasConcept C2776203516 @default.
- W4378834372 hasConcept C2777752497 @default.
- W4378834372 hasConcept C2777752580 @default.
- W4378834372 hasConcept C3018710434 @default.
- W4378834372 hasConcept C55493867 @default.
- W4378834372 hasConcept C71924100 @default.
- W4378834372 hasConceptScore W4378834372C141105273 @default.
- W4378834372 hasConceptScore W4378834372C147483822 @default.
- W4378834372 hasConceptScore W4378834372C159654299 @default.
- W4378834372 hasConceptScore W4378834372C179223381 @default.
- W4378834372 hasConceptScore W4378834372C185592680 @default.
- W4378834372 hasConceptScore W4378834372C202751555 @default.
- W4378834372 hasConceptScore W4378834372C203014093 @default.
- W4378834372 hasConceptScore W4378834372C207480886 @default.
- W4378834372 hasConceptScore W4378834372C2776027960 @default.
- W4378834372 hasConceptScore W4378834372C2776203516 @default.
- W4378834372 hasConceptScore W4378834372C2777752497 @default.
- W4378834372 hasConceptScore W4378834372C2777752580 @default.
- W4378834372 hasConceptScore W4378834372C3018710434 @default.
- W4378834372 hasConceptScore W4378834372C55493867 @default.
- W4378834372 hasConceptScore W4378834372C71924100 @default.
- W4378834372 hasLocation W43788343721 @default.
- W4378834372 hasOpenAccess W4378834372 @default.
- W4378834372 hasPrimaryLocation W43788343721 @default.
- W4378834372 hasRelatedWork W2037320288 @default.
- W4378834372 hasRelatedWork W2057706989 @default.
- W4378834372 hasRelatedWork W2064926782 @default.
- W4378834372 hasRelatedWork W2782607661 @default.
- W4378834372 hasRelatedWork W3112962973 @default.
- W4378834372 hasRelatedWork W3126718951 @default.
- W4378834372 hasRelatedWork W3212418596 @default.
- W4378834372 hasRelatedWork W4378602265 @default.
- W4378834372 hasRelatedWork W4378602293 @default.
- W4378834372 hasRelatedWork W4380985970 @default.
- W4378834372 isParatext "false" @default.
- W4378834372 isRetracted "false" @default.
- W4378834372 workType "article" @default.