Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378840761> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4378840761 endingPage "423" @default.
- W4378840761 startingPage "417" @default.
- W4378840761 abstract "Microbial natural products are an important source of new drug creation. As more and more microbial whole genomes are sequenced, bioinformatics analysis shows that the natural prod-uct resources contained therein are greatly underestimated. Genome mining is a new strategy for natural product discovery guided by gene cluster sequences. At the same time, it can di-rectly associate the structure of natural products with synthesis pathways, which is conven-ient for biosynthesis and combinatorial biosynthesis research. This paper reviews the repre-sentative examples of successful discovery of novel natural products using genome mining strategy in recent years, which fully shows the great advantage of this strategy in exploring the potential of microbial natural metabolites. It is believed that with the continuous devel-opment and improvement of genome mining methods and technologies, it will be possible to realize the in-depth development of microbial natural product resources.This paper describes the application of combinatorial biosynthesis in new drugs, points out the existing problems and puts forward some feasible suggestions." @default.
- W4378840761 created "2023-06-01" @default.
- W4378840761 creator A5065037360 @default.
- W4378840761 date "2023-04-28" @default.
- W4378840761 modified "2023-10-16" @default.
- W4378840761 title "Discovery of new microbial natural products by genome mining" @default.
- W4378840761 doi "https://doi.org/10.54254/2753-8818/3/20220291" @default.
- W4378840761 hasPublicationYear "2023" @default.
- W4378840761 type Work @default.
- W4378840761 citedByCount "0" @default.
- W4378840761 crossrefType "journal-article" @default.
- W4378840761 hasAuthorship W4378840761A5065037360 @default.
- W4378840761 hasBestOaLocation W43788407611 @default.
- W4378840761 hasConcept C104317684 @default.
- W4378840761 hasConcept C127413603 @default.
- W4378840761 hasConcept C141231307 @default.
- W4378840761 hasConcept C151730666 @default.
- W4378840761 hasConcept C183696295 @default.
- W4378840761 hasConcept C2776608160 @default.
- W4378840761 hasConcept C2779396153 @default.
- W4378840761 hasConcept C41008148 @default.
- W4378840761 hasConcept C54355233 @default.
- W4378840761 hasConcept C55493867 @default.
- W4378840761 hasConcept C60644358 @default.
- W4378840761 hasConcept C70721500 @default.
- W4378840761 hasConcept C74187038 @default.
- W4378840761 hasConcept C86803240 @default.
- W4378840761 hasConceptScore W4378840761C104317684 @default.
- W4378840761 hasConceptScore W4378840761C127413603 @default.
- W4378840761 hasConceptScore W4378840761C141231307 @default.
- W4378840761 hasConceptScore W4378840761C151730666 @default.
- W4378840761 hasConceptScore W4378840761C183696295 @default.
- W4378840761 hasConceptScore W4378840761C2776608160 @default.
- W4378840761 hasConceptScore W4378840761C2779396153 @default.
- W4378840761 hasConceptScore W4378840761C41008148 @default.
- W4378840761 hasConceptScore W4378840761C54355233 @default.
- W4378840761 hasConceptScore W4378840761C55493867 @default.
- W4378840761 hasConceptScore W4378840761C60644358 @default.
- W4378840761 hasConceptScore W4378840761C70721500 @default.
- W4378840761 hasConceptScore W4378840761C74187038 @default.
- W4378840761 hasConceptScore W4378840761C86803240 @default.
- W4378840761 hasIssue "1" @default.
- W4378840761 hasLocation W43788407611 @default.
- W4378840761 hasOpenAccess W4378840761 @default.
- W4378840761 hasPrimaryLocation W43788407611 @default.
- W4378840761 hasRelatedWork W1527449984 @default.
- W4378840761 hasRelatedWork W1581809249 @default.
- W4378840761 hasRelatedWork W1603543036 @default.
- W4378840761 hasRelatedWork W1984554167 @default.
- W4378840761 hasRelatedWork W2088226047 @default.
- W4378840761 hasRelatedWork W2325550854 @default.
- W4378840761 hasRelatedWork W2580346700 @default.
- W4378840761 hasRelatedWork W2952405192 @default.
- W4378840761 hasRelatedWork W3201311513 @default.
- W4378840761 hasRelatedWork W2523851068 @default.
- W4378840761 hasVolume "3" @default.
- W4378840761 isParatext "false" @default.
- W4378840761 isRetracted "false" @default.
- W4378840761 workType "article" @default.