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- W4378840783 abstract "Alzheimers disease (AD) is the main cause of dementia worldwide. Although the pathology of AD is not yet completely understood, it has been widely acknowledged that the biomarkers including beta-amyloid plaques, neurofibrillary tangles and the neuroinflammation induced by these hallmarks contributed to the ADs pathology. Different from the conventional diagnosis of AD which is based on clinical criteria, the modern methods relay on biomarkers imaging and fluid test. Currently, although the treatment of AD is targeted to symptomatic therapy, advanced therapies that target the hallmarks of AD such as anti-beta-amyloid and APOE related therapies are under developing. Here, we will first review the major hypothesis of ADs pathological mechanism and then discuss the methods of diagnosis and treatment of AD which is developed in progress" @default.
- W4378840783 created "2023-06-01" @default.
- W4378840783 creator A5082188402 @default.
- W4378840783 date "2023-04-28" @default.
- W4378840783 modified "2023-10-06" @default.
- W4378840783 title "Review of Alzheimer Disease from Pathology, Diagnosis and APOE Targeted Treatment" @default.
- W4378840783 doi "https://doi.org/10.54254/2753-8818/4/20220676" @default.
- W4378840783 hasPublicationYear "2023" @default.
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