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- W4378841058 abstract "Bacteria constantly evolve and adapt within their ever-changing environments. At the subspecies level, opportunistic bacterial pathogens can exist on a spectrum that ranges from more “commensal like” to those that cause acute clinical infections, with genomic diversity accounting for much of the variation. Whole-genome sequencing can reveal bacterial subspecies at the population level using representative strain collections; however, it is not currently used as a method for classifying high volumes of individual clinical isolates in most veterinary diagnostic laboratories. By contrast, the MALDI-TOF MS platform is commonly used for microbial identification in both human and veterinary diagnostic laboratories. Here we discuss the utilities of both whole-genome sequencing and MALDI-TOF MS platforms for bacterial identification and describe an approach to rapidly translate genomic findings from whole-genome sequencing into MALDI-TOF MS-based assays for the identification of bacterial subspecies of veterinary importance." @default.
- W4378841058 created "2023-06-01" @default.
- W4378841058 creator A5056359568 @default.
- W4378841058 creator A5064877723 @default.
- W4378841058 date "2023-04-18" @default.
- W4378841058 modified "2023-09-26" @default.
- W4378841058 title "From Genomics to MALDI‐TOF MS" @default.
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- W4378841058 doi "https://doi.org/10.1002/9781119814085.ch11" @default.
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